A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer.

Autor: Mineva, Nora D.^1,2 (AUTHOR) nora.mineva@adectopharma.com, Pianetti, Stefania^1,2 (AUTHOR) sonia.das.ay@gmail.com, Das, Sonia G.¹ (AUTHOR) srinisrimi@gmail.com, Srinivasan, Srimathi¹ (AUTHOR) nicobilliald@hotmail.fr, Billiald, Nicolas M.¹ (AUTHOR), Sonenshein, Gail E.^1,2 (AUTHOR) nora.mineva@adectopharma.com

Publikováno v: Pharmaceutics. Apr2024, Vol. 16 Issue 4, p536. 19p.

CD40 Ligand-mediated Activation of the de Novo RelB NF-κB Synthesis Pathway in Transformed B Cells Promotes Rescue from Apoptosis

Autor: Mineva, Nora D. ^‡, Rothstein, Thomas L. ^§, Meyers, John A. ^{‡, §}, Lerner, Adam ^{‡, §}, Sonenshein, Gail E. ^{¶, 1}

Publikováno v: In Journal of Biological Chemistry 15 June 2007 282(24):17475-17485

Additional file 3: Figure S2. of miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells

Autor: Das, Sonia, Romagnoli, Mathilde, Mineva, Nora, Barillé-Nion, Sophie, Jézéquel, Pascal, Campone, Mario, Sonenshein, Gail

Total RNA was isolated from serum samples of TNBC patients or normal individuals and analyzed for miR-720 levels. A Figure depicting Pearson’s correlation coefficient plot for miR-720 expression in patient serum versus the size of the tumor in the

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RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1.: RelB represses ERα transcription by inducing Blimp

Autor: Wang, Xiaobo, Belguise, Karine, O'Neill, Christine F., Sánchez-Morgan, Nuria, Romagnoli, Mathilde, Eddy, Sean, Mineva, Nora, Yu, Ziyang, Min, Chengyin, Trinkaus- Randall, Vickery, Chalbos, Dany, Sonenshein, Gail

Publikováno v: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2009, 29 (14), pp.3832-44. ⟨10.1128/MCB.00032-09⟩

International audience; Aberrant constitutive expression of NF-kappaB subunits, reported in more than 90% of breast cancers and multiple other malignancies, plays pivotal roles in tumorigenesis. Higher RelB subunit expression was demonstrated in estr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::de134b9d2825cefda89d99e57d8dc144
https://www.hal.inserm.fr/inserm-00396241/document