Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Mineo SHIMIZU"'
Autor:
Mineo Shimizu, Shunro Endo, Kazuyuki Sugihara, Shoichi Nagai, Masanori Kurimoto, Yasushi Mizumaki, Michiharu Nishijima, Hironaga Kamiyama, Akira Takaku, Yutaka Hirashima
Publikováno v:
Brain Research. 950:254-260
Panax ginseng is a traditional Chinese herb with a wide range of therapeutic benefits. Recent studies focusing on its effect on the central nervous system have revealed that ginseng has neurotrophic effects including differentiation of neurons. Howev
Publikováno v:
Phytotherapy Research. 11:446-449
Forty-one flavonoids of the flavone and flavonol types were investigated for their antioxidative activity using a lipid peroxidation generation system mediated by the addition of H2O2/Fe2+ to rat liver homogenate. The results showed that both types s
Autor:
Takako Yokozawa, Atsutoshi Tsuji, Mineo Shimizu, Yasuyuki Fujiwara, Hikokichi Oura, Toshiyuki Kaji, Kunihiko Wakaki, Fumitomo Koizumi, Masao Hattori
Publikováno v:
Phytotherapy Research. 10:224-227
A significant increase in high-density lipoprotein-cholesterol and a tendency for total cholesterol and low-density lipoprotein-cholesterol to decrease were found in parous rats given Hokoei-to orally for 25 days, resulting in improvement of the athe
Publikováno v:
Biological and Pharmaceutical Bulletin. 18:1439-1442
The effects of Panax ginseng ethanol extract and its water (WSF)- and lipid-soluble (LSF) fractions on the scopolamine-induced disruption of radial maze performance in rats were examined. Ginseng root was refluxed with ethanol, and WSF and LSF were p
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1790-1795
The CHCl3 extract of Matteccia orientalis showed very strong hypoglycemic activity in streptozotocin (STZ)-induced diabetic rats. A new C-methyl flavanone derivative, 2'-hydroxymatteucinol (3) was isolated from the hypoglycemic activity bearing fract
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:1238-1243
Ethyl acetate- and n-butanol-soluble fractions of the leaves of Morus insignis showed a significant hypoglycemic activity on streptozotocin (STZ)-induced hyperglycemic rats. From these hypoglycemic activity-showing fractions, two new compounds, mulbe
Publikováno v:
ChemInform. 28
A new triterpene ester, 3-O-trans-feruloyl euscaphic acid, was isolated from the leaves of Eriobotrya japonica. The structure of this compound was elucidated by means of chemical and spectroscopic studies.
Autor:
Hua Bai, Mineo Shimizu, Shougo Kuze, Naokata Morita, Yusuke Ito, Toshimitsu Hayashi, Munehisa Arisawa
Publikováno v:
Journal of Natural Products. 54:898-901
In view of the observation that a CHCl3-soluble fraction of the MeOH extract of Chrysosplenium grayanum has shown cytotoxic activity in the KB cell in vitro system, the fraction has been further fractionated to furnish five known flavonoids (chrysosp
Autor:
Imai Kunihiro, Naokata Morita, Mineo Shimizu, Suzui Akio, Ueda Yutaka, Ishikura Masatoshi, Nakayama Hajime, Satoshi Terashima
Publikováno v:
Chemical and Pharmaceutical Bulletin. 38:2733-2736
For several years we have screened natural products having aldose reductase (AR) inhibitory activity. 3, 3', 4-Tri-O-methylellagic acid 4'-sulfate potassium salt (2) was isolated from a Mexican herb "Sinfito" (Potentilla candicans) as a potent AR inh
Autor:
Akio Iwashima, Munehisa Arisawa, Atsuko Nishino, Yoshiko Satomi, Mineo Shimizu, Hoyoku Nishino
Publikováno v:
Phytotherapy Research. 9:222-224
Flavonol aglycones from the genus Chrysosplenium showed potential antitumour-promoter activity. Three flavonols, oxyayanin A and chrysosplenols D and E, markedly inhibited the incorporation of 32Pi into phospholipids of confluent HeLa cells stimulate