Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mineo Abe"'
Autor:
Wei-Ying Ma, Eri Murata, Koyo Ueda, Yoshihiro Kuroda, Ming-Hui Cao, Mineo Abe, Kenji Shigemi, Munetaka Hirose
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 1, Pp 79-84 (2010)
Nerve growth factor (NGF) and its high-affinity receptor, TrkA, are one of the targets in the production of new drugs for the treatment of neuropathic pain. NGF contributes to both the initiation and maintenance of sensory abnormalities after periphe
Externí odkaz:
https://doaj.org/article/b6f9c57fa63e48a383dcca5573bfd4d0
Autor:
Munetaka Hirose, Mayumi Takatori, Yoshihiro Kuroda, Mineo Abe, Eri Murata, Tetsuro Isada, Koyo Ueda, Kenji Shigemi, Masayuki Shibazaki, Fumihiro Shimizu, Masashi Hirata, Keita Fukazawa, Masahiro Sakaguchi, Kyoko Kageyama, Yoshifumi Tanaka
Publikováno v:
Journal of Pharmacological Sciences, Vol 106, Iss 1, Pp 107-113 (2008)
As TrkA, a high-affinity receptor of nerve growth factor (NGF), is a potential target for relieving uncontrolled inflammatory pain, an effective inhibitor of TrkA has been required for pain management. To identify a specific inhibitor of TrkA activit
Externí odkaz:
https://doaj.org/article/d04a07ba24bd4304b386a5f1d1ccf85f
Autor:
Eri Murata, Kenji Shigemi, Munetaka Hirose, Mineo Abe, Wei-Ying Ma, Koyo Ueda, Ming-Hui Cao, Yoshihiro Kuroda
Publikováno v:
Journal of Pharmacological Sciences, Vol 114, Iss 1, Pp 79-84 (2010)
Nerve growth factor (NGF) and its high-affinity receptor, TrkA, are one of the targets in the production of new drugs for the treatment of neuropathic pain. NGF contributes to both the initiation and maintenance of sensory abnormalities after periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1048a2ff50005b479810f0a742abdd43
https://doi.org/10.1254/jphs.10119fp
https://doi.org/10.1254/jphs.10119fp
Publikováno v:
Journal of Peptide Science. 15:327-336
In an attempt to develop non-ATP-competitive inhibitors of the autophosphorylation of IR, the effects of the synthetic peptides, Ac-DIY1158ET-NH2 and Ac-DY1162Y1163RK-NH2, on the phosphorylation of IR were studied in vitro. The peptides were derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c806641944b2a75b24cbc22f8032ed3b
https://doi.org/10.1002/psc.1114
https://doi.org/10.1002/psc.1114
Autor:
Munetaka Hirose, Minoru Nakano, Tetsurou Handa, Yoshihiko Watanabe, Yoshihiro Kuroda, Mineo Abe
Publikováno v:
British Journal of Pharmacology. 147:402-411
1. Inhibition of uncontrolled epidermal growth factor receptor (EGFR) is one of the approaches for the treatment of breast and lung cancers. We designed oligopeptides consisting of amino-acid sequences of the major (Y1068, Y1148, and Y1173) and minor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3e3d87f047b3c589951942539600ff
https://doi.org/10.1038/sj.bjp.0706634
https://doi.org/10.1038/sj.bjp.0706634
Autor:
Shiroh Futaki, Kazuhide Miyamoto, Ikuhiko Nakase, Emi Tasaki, Eri Murata, Nahoko Kato-Kogoe, Yoshihiro Kuroda, Mineo Abe, Koyo Ueda, Munetaka Hirose, Yumi Tohyama
Publikováno v:
European journal of pharmacology. 698(1-3)
Epidermal growth factor (EGF) receptor plays a crucial role in the biology of human cancer, and is a highly appropriate target for anticancer agents. We have previously designed oligopeptides containing the amino acid sequences around autophosphoryla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536123994070645d71662ea86c4754c9
https://pubmed.ncbi.nlm.nih.gov/23085023
https://pubmed.ncbi.nlm.nih.gov/23085023
Autor:
Tetsurou Handa, Minoru Nakano, Masaki Kato, Yoshihiro Kuroda, Munetaka Hirose, Mineo Abe, Yoshihiko Watanabe, Masahiro Murakami
Publikováno v:
Biopolymers. 89(1)
Previously we found that short peptides surrounding major autophosphorylation sites of EGFR (VPEY(1068)INQ, DY(1148)QQD, and ENAEY(1173)LR) suppress phosphorylation of purified EGFR to 30-50% at 4000 microM. In an attempt to improve potencies of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02959e8b263e5ae49db5b637f82d3563
https://pubmed.ncbi.nlm.nih.gov/17849478
https://pubmed.ncbi.nlm.nih.gov/17849478