Výsledky vyhledávání - "Minelva R Nanton"

Akademický článek

Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria.

Autor: Jason P Mooney, Seung-Joo Lee, Kristen L Lokken, Minelva R Nanton, Sean-Paul Nuccio, Stephen J McSorley, Renée M Tsolis

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0004027 (2015)

In immunocompetent individuals, non-typhoidal Salmonella serovars (NTS) are associated with gastroenteritis, however, there is currently an epidemic of NTS bloodstream infections in sub-Saharan Africa. Plasmodium falciparum malaria is an important ri

Externí odkaz: https://doaj.org/article/4648094bb29f4d598f0b5aed8df3b5bf

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Cutting Edge: B Cells Are Essential for Protective Immunity against Salmonella Independent of Antibody Secretion

Autor: Mark J. Shlomchik, Sing Sing Way, Stephen J. McSorley, Minelva R. Nanton

Publikováno v: The Journal of Immunology. 189:5503-5507

Typhoid fever and nontyphoidal bacteremia caused by Salmonella remain critical human health problems. B cells are required for protective immunity to Salmonella, but the mechanism of protection remains unclear. In this study, we immunized wild-type,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d67b904c1c20dbc2fb7d1e80a7a68a27
https://doi.org/10.4049/jimmunol.1201413

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Identification of a common immune signature in murine and human systemic Salmonellosis

Autor: Minelva R. Nanton, Robert S. Heyderman, Chisomo L. Msefula, Philip L. Felgner, Renée M. Tsolis, Stephen J. McSorley, Francesca Necchi, Matthew A. Kayala, Li Liang, Jennifer N. Heath, Esther N. Gondwe, Peter J. Hart, Seung-Joo Lee, D. Huw Davies, Silvia Juarez, Calman A. MacLennan

Publikováno v: Proceedings of the National Academy of Sciences. 109:4998-5003

Despite the importance of Salmonella infections in human and animal health, the target antigens of Salmonella -specific immunity remain poorly defined. We have previously shown evidence for antibody-mediating protection against invasive Salmonellosis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5315d5890dcb53e4e6e58f301f6b0bcc
https://doi.org/10.1073/pnas.1111413109

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Culling of Activated CD4 T Cells during Typhoid Is Driven by Salmonella Virulence Genes

Autor: Stephen J. McSorley, Minelva R. Nanton, Amanda M. Griffin, Aparna Srinivasan

Publikováno v: The Journal of Immunology. 182:7838-7845

Pathogen-specific CD4 T cells are activated within a few hours of oral Salmonella infection and are essential for protective immunity. However, CD4 T cells do not participate in bacterial clearance until several weeks after infection, suggesting that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c59f884b67195e51c3a1e13cbfdfdb3
https://doi.org/10.4049/jimmunol.0900382

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Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria

Autor: Sean Paul Nuccio, Seung-Joo Lee, Jason P. Mooney, Kristen L. Lokken, Stephen J. McSorley, Minelva R. Nanton, Renée M. Tsolis

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0004027 (2015)
PLoS neglected tropical diseases, vol 9, iss 9
Mooney, JP; Lee, SJ; Lokken, KL; Nanton, MR; Nuccio, SP; McSorley, SJ; et al.(2015). Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria. PLoS Neglected Tropical Diseases, 9(9), e0004027. doi: 10.1371/journal.pntd.0004027. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/9665n4fq
PLoS Neglected Tropical Diseases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94849bf55e96ffb6450a0965da091edc
http://europepmc.org/articles/PMC4569369?pdf=render

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Selective culling of high avidity antigen-specific CD4+ T cells after virulent Salmonella infection

Autor: James M, Ertelt, Tanner M, Johanns, Margaret A, Mysz, Minelva R, Nanton, Jared H, Rowe, Marijo N, Aguilera, Sing Sing, Way

Publikováno v: Immunology. 134(4)

Typhoid fever is a persistent infection caused by host-adapted Salmonella strains adept at circumventing immune-mediated host defences. Given the importance of T cells in protection, the culling of activated CD4+ T cells after primary infection has b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::958b54efb629e77a608d7536a799e8ae
https://pubmed.ncbi.nlm.nih.gov/22044420

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Innate immune activation during Salmonella infection initiates extramedullary erythropoiesis and splenomegaly

Autor: Hope O'Donnell, Stephen J. McSorley, Amy Jackson, Adovi D. Akue, Minelva R. Nanton

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 185(10)

Systemic Salmonella infection commonly induces prolonged splenomegaly in murine or human hosts. Although this increase in splenic cellularity is often assumed to be due to the recruitment and expansion of leukocytes, the actual cause of splenomegaly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85b415ff69c5d8e3ef564310b2d5f0a
https://pubmed.ncbi.nlm.nih.gov/20952675

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