Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Mineko, Tomomura"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Neurons extend long processes known as axons and dendrites, through which they communicate with each other. The neuronal circuits formed by the axons and dendrites are the structural basis of higher brain functions. The formation and maintenance of t
Externí odkaz:
https://doaj.org/article/671889de71834732b6fcb2ca587987ef
Publikováno v:
Medicines, Vol 8, Iss 8, p 41 (2021)
Blood calcium homeostasis is critical for biological function. Caldecrin, or chymotrypsin-like elastase, was originally identified in the pancreas as a serum calcium-decreasing factor. The serum calcium-decreasing activity of caldecrin requires the t
Externí odkaz:
https://doaj.org/article/2934ef00e44a4aca8d24f33803bff9d4
Autor:
Mitsunori Fukuda, Taro Saito, Anni Huo, Shigeo Murayama, Takeshi Iwatsubo, Mineko Tomomura, Ran Wei, Shikito Ikeda, Wataru Araki, Masato Hasegawa, Yutaka Sato, Kanae Ando, Tetsuya Takano, Kaoru Yamada, Keisuke Komaki, Shin-ichi Hisanaga, Aoi Fukuchi, Fuyuki Kametani, Akiko Asada
Publikováno v:
The Journal of Biochemistry. 170:729-738
Lemur tail kinase 1 (LMTK1), previously called apoptosis-associated tyrosine kinase (AATYK), is an endosomal Ser/Thr kinase. We recently reported that LMTK1 regulates axon outgrowth, dendrite arborization and spine formation via Rab11-mediated vesicl
Autor:
Taro Saito, Yuta Sato, Shin-ichi Hisanaga, Arika Sugiyama, Michihiro Igarashi, Kanae Ando, Ran Wei, Mitsunori Fukuda, Miyuki Takahashi, Hironori Nishino, Mineko Tomomura, Motohiro Nozumi
Publikováno v:
The Journal of Biochemistry. 168:23-32
Lemur kinase 1 (LMTK1) is a membrane-bound Ser/Thr kinase that is expressed in neurons. There are two splicing variants of LMTK1 with different membrane binding modes, viz., cytosolic LMTK1A that binds to membranes through palmitoylation at the N-ter
Autor:
Yoshiaki Sugita, Koichi Takao, Yoshihiro Uesawa, Akito Tomomura, Mineko Tomomura, Kaori Hoshi, Hiroshi Sakagami, Junko Nagai, Haixia Shi, Kenjiro Bandow
Publikováno v:
Anticancer Research. 40(1):87-95
Background/Aim: Very few studies are available about the biological activity of 3-styrylchromones. Our previous study demonstrated the importance of methoxy group at 6-position of the chromone ring and hydroxyl group at 4’-position of phenyl group
Autor:
Yosuke Iijima, Shinji Kito, Shigenobu Tone, Yukari Koga-Ogawa, Akiyoshi Shiroto, Daisuke Ueda, Tadamasa Nobesawa, Sachie Nakatani, Nobuaki Tamura, Giichirou Nakaya, Kenji Kobata, Angel David-Gonzalez, Hiroshi Sakagami, René García-Contreras, Hiroshi Takeshima, Mineko Tomomura
Publikováno v:
In Vivo
Background In order to investigate the combination effect of anticancer drugs and X-ray irradiation on neurotoxic side-effects (neurotoxicity), a method that provides homogeneously X-ray-irradiated cells was newly established. Materials and methods P
Autor:
Koichi Takao, Hiroshi Sakagami, Junko Nagai, Haixia Shi, Kenjiro Bandow, Nao Yoshida, Mineko Tomomura, Natsuko Sezaki, Yoshiaki Sugita, Akito Tomomura, Yoshihiro Uesawa
Publikováno v:
Anticancer Research. 39:6479-6488
BACKGROUND/AIM 4H-1-Benzopyran-4-one (chromone), present in various flavonoids as a backbone structure, has been used for the synthesis of anticancer drugs. The study aimed at investigating the cytotoxicity of eight 2-arylazolylchromones and twelve 2
Autor:
Hiroshi Sakagami, Haixia Shi, Kenjiro Bandow, Mineko Tomomura, Akito Tomomura, Misaki Horiuchi, Tomohiro Fujisawa, Takaaki Oizumi
Publikováno v:
Molecules, Vol 23, Iss 8, p 1840 (2018)
Previous studies of the neuroprotective activity of polyphenols have used ununiform culture systems, making it difficult to compare their neuroprotective potency. We have established a new and simple method for preparing differentiated PC12 cells by
Externí odkaz:
https://doaj.org/article/c1c4890f3fe84127a7a62fb75e649bfd
Autor:
Hiroshi Sakagami, Mineko Tomomura
Publikováno v:
Medicines, Vol 5, Iss 1, p 21 (2018)
This review article summarizes the recent progress in dental applications of natural products. Catechin gel showed selective antimicrobial activity, whereas the alkaline extract of various plant species rich in lignin carbohydrate complex (LCC) showe
Externí odkaz:
https://doaj.org/article/232aa7bc68a44e2dab33064eff4f7207
Autor:
Mineko Tomomura, Ryuichiro Suzuki, Yoshiaki Shirataki, Hiroshi Sakagami, Nobuaki Tamura, Akito Tomomura
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130174 (2015)
Rhinacanthin C is a naphthoquinone ester with anti-inflammatory activity, found in Rhinacanthus nasutus (L) Kurz (Acanthaceae). We found that rhinacanthin C inhibited osteoclast differentiation stimulated by the receptor activator of nuclear factor-
Externí odkaz:
https://doaj.org/article/4e5d1489add24e62a82d8b9015b0cb7c