Výsledky vyhledávání - "Mindy S. Thompson"

Akademický článek

MgADP Promotes Myosin Head Movement toward Actin at Low [Ca2+] to Increase Force Production and Ca2+-Sensitivity of Contraction in Permeabilized Porcine Myocardial Strips

Autor: Peter O. Awinda, Weikang Ma, Kyrah L. Turner, Jing Zhao, Henry Gong, Mindy S. Thompson, Kenneth S. Campbell, Thomas C. Irving, Bertrand C. W. Tanner

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 23, p 15084 (2022)

Myosin cross-bridges dissociate from actin following Mg2+-adenosine triphosphate (MgATP) binding. Myosin hydrolyses MgATP into inorganic phosphate (Pi) and Mg2+-adenosine diphosphate (ADP), and release of these hydrolysis products drives chemo-mechan

Externí odkaz: https://doaj.org/article/4b3d2da720e0436f80c18278c270a1ce

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Sarcomere length affects Ca2+ sensitivity of contraction in ischemic but not non-ischemic myocardium

Autor: Bertrand C.W. Tanner, Peter O. Awinda, Keinan B. Agonias, Seetharamaiah Attili, Cheavar A. Blair, Mindy S. Thompson, Lori A. Walker, Thomas Kampourakis, Kenneth S. Campbell

Publikováno v: Journal of General Physiology. 155

In healthy hearts, myofilaments become more sensitive to Ca2+ as the myocardium is stretched. This effect is known as length-dependent activation and is an important cellular-level component of the Frank–Starling mechanism. Few studies have measure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce2dffbc1c0a3742a1ea5ac92ad6d6a4
https://doi.org/10.1085/jgp.202213200

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The Length-Dependent Increase in Ca 2+-Sensitivity of Contraction is Eliminated in Myocardium from Patients with Non-Ischemic Heart Failure

Autor: Bertrand C.W. Tanner, Peter O. Awinda, Keinan B. Agonias, Cheavar A. Blair, Mindy S. Thompson, Lori A. Walker, Thomas Kampourakis, Kenneth S. Campbell

Publikováno v: SSRN Electronic Journal.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e202c43f178cc54f96384ddd6f51bd37
https://doi.org/10.2139/ssrn.4088694

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Anti-S2 peptides target cardiac myosin for in vivo responses

Autor: Douglas D. Root, Dua'a Quedan, Motamed Qadan, Bryana M. Levitan, Mindy S. Thompson, Kenneth S. Campbell

Publikováno v: Biophysical Journal. 121:397a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d56fa1713feb794080a41999f1be14e9
https://doi.org/10.1016/j.bpj.2021.11.782

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Effects of mavacamten and sarcomere length on the Ca2+-sensitivity of permeabilized myocardial strips from patients with heart failure

Autor: Bertrand C.W. Tanner, Peter O. Awinda, Yemeserach Bishaw, Marissa Watanabe, Katherine L. Thompson, Mindy S. Thompson, Emma J. Birks, Kenneth S. Campbell

Publikováno v: Biophysical Journal. 121:107a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42657d41ff20930ab3aad2fb14aae108
https://doi.org/10.1016/j.bpj.2021.11.2182

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Akademický článek

MgADP Promotes Myosin Head Movement toward Actin at Low [Ca 2+ ] to Increase Force Production and Ca 2+ -Sensitivity of Contraction in Permeabilized Porcine Myocardial Strips.

Autor: Awinda, Peter O.¹ (AUTHOR), Ma, Weikang^2,3 (AUTHOR), Turner, Kyrah L.⁴ (AUTHOR), Zhao, Jing⁵ (AUTHOR), Gong, Henry³ (AUTHOR), Thompson, Mindy S.^6,7 (AUTHOR), Campbell, Kenneth S.^6,7 (AUTHOR), Irving, Thomas C.^2,3 (AUTHOR), Tanner, Bertrand C. W.¹ (AUTHOR) bertrand.tanner@wsu.edu

Publikováno v: International Journal of Molecular Sciences. Dec2022, Vol. 23 Issue 23, p15084. 14p.

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Periodical

Researchers at Washington State University Target Heart Failure (Sarcomere Length Affects Ca2+ Sensitivity of Contraction In Ischemic but Not Non-ischemic Myocardium).

Publikováno v: Cardiovascular Week; 3/13/2023, p737-737, 1p

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