Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mincheol Kwon"'
Autor:
Gyeongjo Hwang, Mincheol Kwon, Dongjin Seo, Dae Hoon Kim, Daehwan Lee, Kiwon Lee, Eunyoung Kim, Mingeun Kang, Jin-Hyeob Ryu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 2, Pp 102186- (2024)
Recent studies have highlighted the effectiveness of using antisense oligonucleotides (ASOs) for cellular RNA regulation, including targets that are considered undruggable; however, manually designing optimal ASO sequences can be labor intensive and
Externí odkaz:
https://doaj.org/article/adb774eda8cc465c8bbed7e6795d66a9
Autor:
Mincheol Kwon, Sung-Kyun Ko, Mina Jang, Gun-Hee Kim, In-Ja Ryoo, Sangkeun Son, Hyung Won Ryu, Sei-Ryang Oh, Won-Kyu Lee, Bo Yeon Kim, Jae-Hyuk Jang, Jong Seog Ahn
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1481-1488 (2019)
Indoleamine 2,3-dioxygenase 1 (IDO1), a tryptophan catabolising enzyme, is known as a tumour cell survival factor that causes immune escape in several types of cancer. Flavonoids of Sophora flavescens have a variety of biological benefits for humans;
Externí odkaz:
https://doaj.org/article/6df726e44a7343adad658768e4e01d78
Autor:
Taehoon Oh, Mincheol Kwon, Jae Sik Yu, Mina Jang, Gun-Hee Kim, Ki Hyun Kim, Sung-Kyun Ko, Jong Seog Ahn
Publikováno v:
Pharmaceutics, Vol 12, Iss 12, p 1229 (2020)
Studies on ethanol-induced stress and acetaldehyde toxicity are actively being conducted, owing to an increase in alcohol consumption in modern society. In this study, ent-peniciherqueinone (EPQ) isolated from a Hawaiian volcanic soil-associated fung
Externí odkaz:
https://doaj.org/article/d0e383602ee748e283a8ecbbde1c2532
Autor:
Jamil Azzi, Qian Yin, Mayuko Uehara, Shunsuke Ohori, Li Tang, Kaimin Cai, Takaharu Ichimura, Martina McGrath, Omar Maarouf, Eirini Kefaloyianni, Scott Loughhead, Jarolim Petr, Qidi Sun, Mincheol Kwon, Stefan Tullius, Ulrich H. von Andrian, Jianjun Cheng, Reza Abdi
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1202-1213 (2016)
Active-targeted delivery to lymph nodes represents a major advance toward more effective treatment of immune-mediated disease. The MECA79 antibody recognizes peripheral node addressin molecules expressed by high endothelial venules of lymph nodes. By
Externí odkaz:
https://doaj.org/article/1c98e1bb63474c90aa0e9a1d403db62a
Autor:
Li Tang, Jamil Azzi, Mincheol Kwon, Marwan Mounayar, Rong Tong, Qian Yin, Robert Moore, Nikolaos Skartsis, Timothy M. Fan, Reza Abdi, Jianjun Cheng
Publikováno v:
Journal of Transplantation, Vol 2012 (2012)
We encapsulated cyclosporine A (CsA) in poly(ethylene glycol)-b-poly(d,l-lactide-co-glycolide) (PEG-PLGA) nanoparticles (NPs) by nanoprecipitation of CsA and PEG-PLGA. The resulting CsA/PEG-PLGA-NPs were
Externí odkaz:
https://doaj.org/article/1c09ecdf1ef148ac9ee459d0cb99d0e1
Autor:
Mincheol Kwon, Jun-Pil Jang, Jong Seog Ahn, Kyung Taek Heo, Sung-Kyun Ko, Tae Hoon Oh, Jae-Hyuk Jang, Gil Soo Kim, Jung-Sook Lee, Byeongsan Lee, Young-Soo Hong
Publikováno v:
RSC Advances. 11:19805-19812
A bioassay-guided investigation led to the isolation of three new carbazole glycosides, jejucarbazoles A–C (1–3), from Streptomyces sp. KCB15JA151. Their planar structures were elucidated by detailed NMR and MS spectroscopic analysis with a liter
Autor:
Geum Jin Kim, Hyukjae Choi, Jong Seog Ahn, Jun-Pil Jang, Jung-Sook Lee, Sung-Kyun Ko, Jae-Hyuk Jang, Tae Hoon Oh, Byeongsan Lee, Young-Soo Hong, Mincheol Kwon, Gil Soo Kim
Publikováno v:
The Journal of Antibiotics. 73:859-862
LC/MS-based chemical screening of culture extract led to a new highly oxygenated angucycline derivative, grecocycline D (1), from Streptomyces sp. KCB15JA014, isolated from a soil sample of Oedolgae in Jeju Island, Korea. The planar structure was det
Autor:
Mincheol Kwon, Taehoon Oh, Mina Jang, Gun-Hee Kim, Jung-Hee Kim, Hyung Won Ryu, Sei-Ryang Oh, Jae-Hyuk Jang, Jong Seog Ahn, Sung-Kyun Ko
Publikováno v:
European journal of pharmacology. 923
Kurarinone (KR), a naturally occurring flavonoid in Sophora flavescens Aiton and a traditional herbal medicine, reportedly has anti-cancer activity against various cancer types both in vitro and in vivo. However, the cellular mechanism of KR remains
Autor:
Jae Sik Yu, Se Yun Jeong, Chunshun Li, Taehoon Oh, Mincheol Kwon, Jong Seog Ahn, Sung-Kyun Ko, Yoon-Joo Ko, Shugeng Cao, Ki Hyun Kim
Publikováno v:
Archives of pharmacal research. 45(2)
Phenalenone derivatives sourced from fungi are polyketides that have attracted significant interest because of their diverse chemical structures and potential bioactivities. As part of our ongoing quest to discover novel natural products with biologi
Jejucarbazoles A-C, carbazole glycosides with indoleamine 2,3-dioxygenase 1 inhibitory activity from
Autor:
Gil Soo, Kim, Jun-Pil, Jang, Mincheol, Kwon, Tae Hoon, Oh, Kyung Taek, Heo, Byeongsan, Lee, Jung-Sook, Lee, Sung-Kyun, Ko, Young-Soo, Hong, Jong Seog, Ahn, Jae-Hyuk, Jang
Publikováno v:
RSC advances. 11(32)
A bioassay-guided investigation led to the isolation of three new carbazole glycosides, jejucarbazoles A-C (1-3), from