Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Minchenko Oleksandr H."'
Autor:
Minchenko Oleksandr H., Abramchuk Anastasiia I., Khita Olena O., Sliusar Myroslava Y., Viletska Yuliia M., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 206-214 (2024)
Objective. Carboxypeptidase E (CPE) plays an important role in the biosynthesis of neurotransmitters and peptide hormones including insulin. It also promotes cell proliferation, survival, and invasion of tumor cells. The endoplasmic reticulum stress,
Externí odkaz:
https://doaj.org/article/3009a13843a6451d8b39bd696d3a6145
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Viletska Yuliia M., Luzina Olha Y., Danilovskyi Serhiy V., Minchenko Dmytro O.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 144-152 (2024)
Objective. Serine hydroxymethyltransferase (SHMT2) plays a multifunctional role in mitochondria (folate-dependent tRNA methylation, translation, and thymidylate synthesis). The endoplasmic reticulum stress, hypoxia, and glucose and glutamine supply a
Externí odkaz:
https://doaj.org/article/8492f2f39bcd4c8f97216ef7a540237f
Autor:
Minchenko Oleksandr H., Sliusar Myroslava Y., Khita Olena O., Minchenko Dmytro O., Viletska Yuliia M., Halkin Oleh V., Levadna Liudmyla O., Cherednychenko Anastasiia A., Khikhlo Yevgen P.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 91-100 (2024)
Objective. Glucose and glutamine supply as well as serine synthesis and endoplasmic reticulum (ER) stress are important factors of glioblastoma growth. Previous studies showed that the knockdown of ERN1 (ER to nucleus signaling 1) suppressed glioblas
Externí odkaz:
https://doaj.org/article/fe2223a129ea40ada897520c36364990
Autor:
Krasnytska Daria A., Khita Olena O., Viletska Yuliia M., Minchenko Dmytro O., Halkin Oleh V., Rudnytska Olha V., Hoian Sofiia L., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 47-56 (2024)
Homeobox genes play an important role in health and disease including oncogenesis. The present investigation aimed to study ERN1-dependent hypoxic regulation of the expression of genes encoding homeobox proteins MEIS (zinc finger E-box binding homeob
Externí odkaz:
https://doaj.org/article/f7aa9d84f6224def9fd6df5e506bf5f0
Autor:
Minchenko Dmytro O., Khita Olena O., Viletska Yuliia M., Sliusar Myroslava Y., Rudnytska Olha V., Kozynkevych Halyna E., Bezrodnyi Borys H., Khikhlo Yevgen P., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 58, Iss 1, Pp 1-10 (2024)
Objective. Glucocorticoids are important stress-responsive regulators of insulin-dependent metabolic processes realized through specific changes in genome function. The aim of this study was to investigate the impact of cortisol on insulin receptor a
Externí odkaz:
https://doaj.org/article/b609e490dc3c40e88c18f131f83ee809
Autor:
Sliusar Myroslava Y., Minchenko Dmytro O., Khita Olena O., Tsymbal Dariia O., Viletska Yuliia M., Luzina Olha Y., Danilovskyi Serhij V., Ratushna Oksana O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 252-261 (2023)
Objective. Serine synthesis as well as endoplasmic reticulum stress and hypoxia are important factors of malignant tumor growth including glioblastoma. Previous studies have shown that the knockdown of ERN1 (endoplasmic reticulum to nucleus signaling
Externí odkaz:
https://doaj.org/article/4aefa70ee11343659d21bbc7b8f50335
Autor:
Minchenko Dmytro O., Rudnytska Olha V., Khita Olena O., Kulish Yuliia V., Viletska Yuliia M., Halkin Oleh V., Danilovskyi Serhiy V., Ratushna Oksana O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 162-172 (2023)
Objective. Single-walled carbon nanotubes (SWCNTs) are considered to be one of the nanomaterials attractive for biomedical applications, particularly in the health sciences as imaging probes and drug carriers, especially in the field of cancer therap
Externí odkaz:
https://doaj.org/article/18a811d499954a08a86a5931c08b6421
Autor:
Krasnytska Dariia O., Viletska Yuliia M., Minchenko Dmytro O., Khita Olena O., Tsymbal Dariia O., Cherednychenko Anastasiia A., Kozynkevych Halyna E., Oksiom Nataliia S., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 57, Iss 1, Pp 37-47 (2023)
Objective. Homeobox genes play a fundamental role in the embryogenesis, but some of them have been linked to oncogenesis. The present study is aimed to investigate the impact of glucose and glutamine deprivations on the expression of homeobox genes s
Externí odkaz:
https://doaj.org/article/8785ec42d410459e90ae227b34b9bbf3
Autor:
Shatokhina Hanna O., Khita Olena O., Minchenko Dmytro O., Tsymbal Dariia O., Luzina Olha R., Danilovskyi Serhiy V., Sliusar Myroslava Y., Levadna Liudmyla O., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 56, Iss 4, Pp 254-264 (2022)
Objective. The aim of the present study was to investigate the expression of pyruvate dehydrogenase genes such as PDHA1, PDHB, DLAT, DLD, and PDHX in U87 glioma cells in response to glutamine and glucose deprivations in control glioma cells and endop
Externí odkaz:
https://doaj.org/article/6cf314c9701640bba86af4adc822845c
Autor:
Rudnytska Olha V., Kulish Yuliia V., Khita Olena O., Minchenko Dmytro O., Tsymbal Dariia O., Viletska Yuliia M., Sliusar Myroslava Y., Trufanova Dariia D., Minchenko Oleksandr H.
Publikováno v:
Endocrine Regulations, Vol 56, Iss 3, Pp 216-226 (2022)
Objective. Nanographene oxide, an oxidation derivative of graphene, is considered to be one of the nanomaterials attractive for biomedical applications, although this nanomaterial is toxic. The increasing exploitation of graphene-based materials nece
Externí odkaz:
https://doaj.org/article/8638edac92d24b09a04666ecb13c06f6