Glycosylation and charge distribution orchestrates the conformational ensembles of a biotechnologically promissory phytase in different pHs - a computational study.

Autor: De Souza TPP; Microbial Biotechnology Laboratory, Universidade Federal de São João Del-Rei, Divinópolis, Minas Gerais, Brazil., Cantão LXS; Laboratory of Bioinformatics and Systems (LBS), Department Of Computer Science, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Rodrigues MQRB; Department of Biosystems Engineering, Universidade Federal de São João Del-Rei, São João Del-Rei, Minas Gerais, Brazil., Gonçalves DB; Department of Biosystems Engineering, Universidade Federal de São João Del-Rei, São João Del-Rei, Minas Gerais, Brazil., Nagem RAP; Institute of Biological Sciences Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Rocha REO; Laboratory of Bioinformatics and Systems (LBS), Department Of Computer Science, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.; Laboratory Of Molecular Modeling and Bioinformatics, Department of Exacts and Biological Sciences (DECEB), Universidade Federal de São João Del-Rei, Sete Lagoas, Minas Gerais, Brazil., Godoi RR; Institute of Biological Sciences Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Lima WJN; Institute of Agricultural Sciences, Universidade Federal de Minas Gerais, Campus Regional de Montes Claros, Montes Claros, Minas Gerais, Brazil., Galdino AS; Microbial Biotechnology Laboratory, Universidade Federal de São João Del-Rei, Divinópolis, Minas Gerais, Brazil., Minardi RCM; Laboratory of Bioinformatics and Systems (LBS), Department Of Computer Science, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Lima LHF; Laboratory Of Molecular Modeling and Bioinformatics, Department of Exacts and Biological Sciences (DECEB), Universidade Federal de São João Del-Rei, Sete Lagoas, Minas Gerais, Brazil.

Publikováno v: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2024 Jul; Vol. 42 (10), pp. 5030-5041. Date of Electronic Publication: 2023 Jun 16.