Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Minal Çalışkan"'
Autor:
Minal Çalışkan, Koichi Tazaki
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Lung cancer is the leading cause of cancer deaths among both men and women, representing approximately 25% of cancer fatalities each year. The treatment landscape for non-small cell lung cancer (NSCLC) is rapidly evolving due to the progress made in
Externí odkaz:
https://doaj.org/article/abda8b7096df45c8a28edd168e60417c
Publikováno v:
PLoS Genetics, Vol 11, Iss 4, p e1005111 (2015)
Rhinovirus (RV) is the most prevalent human respiratory virus and is responsible for at least half of all common colds. RV infections may result in a broad spectrum of effects that range from asymptomatic infections to severe lower respiratory illnes
Externí odkaz:
https://doaj.org/article/5fb630dd1f1e4cc9947167655138f4d8
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107166 (2014)
Epstein-Barr virus (EBV) transformed lymphoblastoid cell lines (LCLs) are a widely used renewable resource for functional genomic studies in humans. The ability to accumulate multidimensional data pertaining to the same individual cell lines, from co
Externí odkaz:
https://doaj.org/article/99c7cc2a25d141ee92198364cc340b73
Publikováno v:
American Journal of Human Genetics
Summary Genome-wide association studies (GWASs) have enabled unbiased identification of genetic loci contributing to common complex diseases. Because GWAS loci often harbor many variants and genes, it remains a major challenge to move from GWASs’ s
Autor:
Katelyn Mika, YoSon Park, Minal Çalışkan, Marco Trizzino, George H. Perry, Vincent J. Lynch, Marcia Holsbach-Beltrame, Christopher D. Brown, Katherine Aracena
Publikováno v:
Genome Research. 27:1623-1633
Gene regulation shapes the evolution of phenotypic diversity. We investigated the evolution of liver promoters and enhancers in six primate species using ChIP-seq (H3K27ac and H3K4me1) to profile cis-regulatory elements (CREs) and using RNA-seq to ch
Autor:
S. Gao, Omar Jabado, Sean E. Connolly, Michael E. Weinblatt, S. Hu, M. Maldonado, D. Galbraith, Minal Çalışkan, Roy Fleischmann
Publikováno v:
Annals of the Rheumatic Diseases. 79:891-892
Background:RA is a systemic autoimmune disease with heterogeneous manifestation. Recent advances in serum proteomics, such as the SomaScan®platform (SomaLogic, Inc., Boulder, USA), allow for a deeper exploration of the protein biomarkers associated
Autor:
Andrea M Berrido, Nicholas J. Hand, Kim M. Olthoff, Daniel J. Rader, Marcia Holsbach Beltrame, Marco Trizzino, Bao-Li Loza, Dong Xin, Struan F.A. Grant, Robert C. Bauer, Michelle E. Leonard, Samuel W. Baker, Elisabetta Manduchi, Minal Çalışkan, Alessandra Chesi, Abraham Shaked, Julian A. Segert, H. Shanker Rao, Matthew E. Johnson, Kenyaita M. Hodge, YoSon Park, Christopher D. Brown, Andrew D. Wells
Publikováno v:
American Journal of Human Genetics
Deciphering the impact of genetic variation on gene regulation is fundamental to understanding common, complex human diseases. Although histone modifications are important markers of gene regulatory regions of the genome, any specific histone modific
Autor:
Christine Billstrand, Geoffrey Chupp, Yoav Gilad, Carole Ober, Sanjiv J. Shah, Jack A. Elias, Minal Çalışkan, Claudia Chavarria, Roberto M. Lang, Darren A. Cusanovich, Jeanne M. DeCara, Amy Mitrano, Sherryl De Leon, Noah Lewellyn, Katelyn Michelini
Publikováno v:
Human Molecular Genetics
Genome-wide association studies (GWASs) have become a standard tool for dissecting genetic contributions to disease risk. However, these studies typically require extraordinarily large sample sizes to be adequately powered. Strategies that incorporat
Autor:
S. Hu, D. Galbraith, Sean E. Connolly, Omar Jabado, Roy Fleischmann, S. Gao, Michael E. Weinblatt, Minal Çalışkan, M. Maldonado
Publikováno v:
Annals of the Rheumatic Diseases. 79:244.1-244
Background:Abatacept (ABA) versus adaliMumab (ADA) comParison in bioLogic-naïvERA subjects with background MTX (AMPLE) was a Phase IIIb clinical trial to compare the safety, efficacy and radiographic outcomes of ABA vs ADA in patients with RA who ex
Autor:
Christopher D. Brown, Marcia Holsbach-Beltrame, Katelyn Mika, Marco Trizzino, Katherine Aracena, YoSon Park, George H. Perry, Vincent J. Lynch, Minal Çalışkan
Gene regulation plays a critical role in the evolution of phenotypic diversity. We investigated the evolution of liver promoters and enhancers in six primate species. We performed ChlP-seq for two histone modifications and RNA-seq to profile cis-regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94ef8961398f47fd16b5f6ce0ec4fde5
https://doi.org/10.1101/083980
https://doi.org/10.1101/083980