Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Minakshi Guha"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67782 (2013)
Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop drug resistance due to the presence of secondary mutations like the T790M mutation on EGFR exon 20. These mutations may ori
Externí odkaz:
https://doaj.org/article/3a01d0b8b1874ea8bfa4e999453b6cb1
Autor:
Vasanth, Karunamoorthy1 (AUTHOR) vasanthkarunamoorthy@gmail.com, Minakshi, Guha Chowdhury1 (AUTHOR), Velu, Karthick2 (AUTHOR), Priya, Tanu1 (AUTHOR), Kumar, R. Mohan3 (AUTHOR), Kaliappan, Ilango4 (AUTHOR), Dubey, Govind Prasad5 (AUTHOR)
Publikováno v:
Journal of Food Biochemistry. Aug2022, Vol. 46 Issue 8, p1-12. 12p.
Autor:
Sylvie Vincent, Zhenqiang Su, Veronica Bunn, Adarsh Joshi, Ziji Yu, Sampurna Chatterjee, Minakshi Guha, Pingkuan Zhang
Publikováno v:
Journal of Clinical Oncology. 40:9108-9108
9108 Background: ctDNA is an important tool to diagnose and monitor mutations in pts with non–small cell lung cancer (NSCLC). We evaluated epidermal growth factor receptor gene ( EGFR) ex20ins mutations in tumor vs plasma samples, assessed changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fba5ec01c9b968ce4969042de67fccf2
https://doi.org/10.1200/jco.2022.40.16_suppl.9108
https://doi.org/10.1200/jco.2022.40.16_suppl.9108
Autor:
Maurizio Ferrari, Elena Castellanos-Rizaldos, Minakshi Guha, Harvey J. Mamon, Laura Cremonesi, Pingfang Liu, Angela Brisci, Coren A. Milbury, G. Mike Makrigiorgos
Publikováno v:
Clinical Chemistry. 58:1130-1138
BACKGROUND Low-level mutations in clinical tumor samples often reside below mutation detection limits, thus leading to false negatives that may impact clinical diagnosis and patient management. COLD-PCR (coamplification at lower denaturation temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2387d300ff40aff7cba1a5cb53ab9710
https://doi.org/10.1373/clinchem.2012.183095
https://doi.org/10.1373/clinchem.2012.183095
Autor:
Donald Kufe, Surender Kharbanda, Minakshi Guha, Caining Jin, Maroof Alam, Hasan Rajabi, Maya Datt Joshi, Rehan Ahmad
Publikováno v:
The Prostate. 72:1659-1668
The mucin 1 (MUC1) heterodimeric oncoprotein is overexpressed in human prostate cancers with aggressive pathologic and clinical features. However, few insights are available regarding the functional role of MUC1 in prostate cancer.Effects of MUC1-C o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9132c6dc476626891748fcec5344a90b
https://doi.org/10.1002/pros.22519
https://doi.org/10.1002/pros.22519
Publikováno v:
Oncogene
One of the pivotal functions of endogenous tumor suppression is to oppose aberrant cell survival, but the molecular requirements of this process are not completely understood. Here, we show that caspase 2, a death effector with largely unknown functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf410b6bed92aa1f1d975d714b9e9b7a
http://europepmc.org/articles/PMC2832727
http://europepmc.org/articles/PMC2832727
Publikováno v:
Cancer Research. 69:4954-4958
Endogenous tumor suppression provides a barrier against oncogenesis, but the molecular requirements of this process are not well understood. Here, we show that the dual specificity phosphatase PTEN, a gene almost universally altered in human tumors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d7d927a7359c09bb148634c8ac5eb0
https://doi.org/10.1158/0008-5472.can-09-0584
https://doi.org/10.1158/0008-5472.can-09-0584
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1102
Detection of low-level mutations is important for cancer biomarker and therapy targets discovery, but reliable detection remains a technical challenge. The newly developed method of CO-amplification at Lower Denaturation temperature PCR (COLD-PCR) he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4971f35a56a1572db47bacbd826d4ef2
https://pubmed.ncbi.nlm.nih.gov/24259002
https://pubmed.ncbi.nlm.nih.gov/24259002
Publikováno v:
Methods in Molecular Biology ISBN: 9781627037266
Detection of low-level mutations is important for cancer biomarker and therapy targets discovery, but reliable detection remains a technical challenge. The newly developed method of CO-amplification at Lower Denaturation temperature PCR (COLD-PCR) he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28b71ebb66d8ddbc2121c666bc277a3e
https://doi.org/10.1007/978-1-62703-727-3_33
https://doi.org/10.1007/978-1-62703-727-3_33
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e67782 (2013)
PLoS ONE, Vol 8, Iss 6, p e67782 (2013)
Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop drug resistance due to the presence of secondary mutations like the T790M mutation on EGFR exon 20. These mutations may ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82622073393fc78fc85e1f1f6c8bcaa2
https://pubmed.ncbi.nlm.nih.gov/23805327
https://pubmed.ncbi.nlm.nih.gov/23805327