Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Minako Ogino"'
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010287 (2022)
The unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase) domain of the vesicular stomatitis virus (VSV) L protein possesses a dual-functional "priming-capping loop" that governs terminal de novo initiation for leader RNA s
Externí odkaz:
https://doaj.org/article/c1f7047384a245dd81f342f59e3ffb07
Autor:
Minako Ogino, Yuriy Fedorov, Drew J. Adams, Kazuma Okada, Naoto Ito, Makoto Sugiyama, Tomoaki Ogino
Publikováno v:
Viruses, Vol 11, Iss 9, p 856 (2019)
Vesicular stomatitis virus (VSV) represents a promising platform for developing oncolytic viruses, as well as vaccines against significant human pathogens. To safely control VSV infection in humans, small-molecule drugs that selectively inhibit VSV i
Externí odkaz:
https://doaj.org/article/c2a7b24b28ca41b587a04ed103a15fc6
Publikováno v:
Viruses, Vol 8, Iss 5, p 144 (2016)
The large (L) protein of rabies virus (RABV) plays multiple enzymatic roles in viral RNA synthesis and processing. However, none of its putative enzymatic activities have been directly demonstrated in vitro. In this study, we expressed and purified a
Externí odkaz:
https://doaj.org/article/50a16cb5e76f4363a450b40c47901f0f
Autor:
Gupta, Nirmala1, Minako Ogino1,2, Watkins, Dean E.2, Tiffany Yu2, Green, Todd J.3, Tomoaki Ogino1,2 tomoaki.ogino@utoledo.edu
Publikováno v:
Journal of Virology. Aug2023, Vol. 97 Issue 8, p1-19. 19p.
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010287 (2022)
The unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase) domain of the vesicular stomatitis virus (VSV) L protein possesses a dual-functional "priming-capping loop" that governs terminal de novo initiation for leader RNA s
Publikováno v:
Nucleic Acids Research
The L proteins of rhabdoviruses, such as vesicular stomatitis virus (VSV) and rabies virus (RABV), possess an unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase) domain with a loop structure protruding into an active site
Autor:
Naoto Ito, Minako Ogino, Yuriy Fedorov, Tomoaki Ogino, Makoto Sugiyama, Drew J. Adams, Kazuma Okada
Publikováno v:
Viruses, Vol 11, Iss 9, p 856 (2019)
Viruses
Volume 11
Issue 9
Viruses
Volume 11
Issue 9
Vesicular stomatitis virus (VSV) represents a promising platform for developing oncolytic viruses, as well as vaccines against significant human pathogens. To safely control VSV infection in humans, small-molecule drugs that selectively inhibit VSV i
Publikováno v:
Nucleic Acids Research
The unconventional mRNA capping enzyme (GDP polyribonucleotidyltransferase, PRNTase; block V) domain in RNA polymerase L proteins of non-segmented negative strand (NNS) RNA viruses (e.g. rabies, measles, Ebola) contains five collinear sequence elemen
Autor:
Minako Ogino, Tomoaki Ogino
Publikováno v:
Journal of Virology. 91
The GDP polyribonucleotidyltransferase (PRNTase) domain of the multifunctional L protein of rhabdoviruses, such as vesicular stomatitis virus (VSV) and rabies virus, catalyzes the transfer of 5′-phospho-RNA (pRNA) from 5′-triphospho-RNA (pppRNA)
Publikováno v:
Journal of virology. 90(2)
Viruses have various mechanisms to duplicate their genomes and produce virus-specific mRNAs. Negative-strand RNA viruses encode their own polymerases to perform each of these processes. For the nonsegmented negative-strand RNA viruses, the polymerase