Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Minako Mikamiyama-Iwata"'
Autor:
Takashi Kawasuji, Brian A. Johns, Hiroshi Yoshida, Jason G. Weatherhead, Toshiyuki Akiyama, Teruhiko Taishi, Yoshiyuki Taoda, Minako Mikamiyama-Iwata, Hitoshi Murai, Ryuichi Kiyama, Masahiro Fuji, Norihiko Tanimoto, Tomokazu Yoshinaga, Takahiro Seki, Masanori Kobayashi, Akihiko Sato, Edward P. Garvey, Tamio Fujiwara
Publikováno v:
Journal of Medicinal Chemistry. 56:1124-1135
This work is a continuation of our initial discovery of a potent monocyclic carbamoyl pyridone human immunodeficiency virus type-1 (HIV-1) integrase inhibitor that displayed favorable antiviral and pharmacokinetic properties. We report herein a serie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1167fb02558e33f61b588c3a9fb8ae3c
https://doi.org/10.1021/jm301550c
https://doi.org/10.1021/jm301550c
Autor:
Takao Shishido, Minako Mikamiyama-Iwata, Yoshiyuki Taoda, Tomokazu Yoshinaga, Ryu Yoshida, Naoko Kurihara, Naoyuki Suzuki, Kenji Morimoto, Noriyuki Kurose, Masayoshi Miyagawa, Hidenori Mikamiyama, Makoto Kawai, Kazunari Hattori, Kenji Tomita, Chika Takahashi-Kageyama, Toshiyuki Akiyama, Kenji Matsuo, Kenji Takaya, Akihiko Sato
Publikováno v:
Bioorganicmedicinal chemistry letters. 26(19)
We report the discovery of a novel series of influenza Cap-dependent EndoNuclease (CEN) inhibitors based on the 4-pyridone-carboxylic acid (PYXA) scaffold, which were found from our chelate library. Our SAR research revealed the lipophilic domain to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69232b20f8a66fc4e31959854f6ec6a1
https://pubmed.ncbi.nlm.nih.gov/27568084
https://pubmed.ncbi.nlm.nih.gov/27568084