Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Minako Matsuo"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
DNA aptamers can bind specifically to biomolecules to modify their function, potentially making them ideal oligonucleotide therapeutics. Herein, we screened for DNA aptamer of melanopsin (OPN4), a blue-light photopigment in the retina, which plays a
Externí odkaz:
https://doaj.org/article/9b35f811bd6b48aaa6c21e06c6728938
Autor:
Rika Numano, Akihiro Goryu, Yoshihiro Kubota, Hirohito Sawahata, Shota Yamagiwa, Minako Matsuo, Tadahiro Iimura, Hajime Tei, Makoto Ishida, Takeshi Kawano
Publikováno v:
FEBS Open Bio, Vol 12, Iss 4, Pp 835-851 (2022)
Genetic modification to restore cell functions in the brain can be performed through the delivery of biomolecules in a minimally invasive manner into live neuronal cells within brain tissues. However, conventional nanoscale needles are too short (len
Externí odkaz:
https://doaj.org/article/8904ddec34774351bd08e76161145020
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1463 (2023)
All organisms maintain an internal clock that matches the Earth’s rotation over a period of 24 h, known as the circadian rhythm. Previously, we established Period1 luciferase (Per1::luc) transgenic (Tg) mice in order to monitor the expression rhyth
Externí odkaz:
https://doaj.org/article/89fe2e8575b542ac9c32b328fa291043
Autor:
Hirofumi Kurita, Shota Takahashi, Atsushi Asada, Minako Matsuo, Kenta Kishikawa, Akira Mizuno, Rika Numano
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144254 (2015)
Electroporation is the most widely used transfection method for delivery of cell-impermeable molecules into cells. We developed a novel gene transfection method, water-in-oil (W/O) droplet electroporation, using dielectric oil and an aqueous droplet
Externí odkaz:
https://doaj.org/article/47cc82dfa7cc430db6e3a505fc0693c7
Autor:
Rika Numano, Akihiro Goryu, Yoshihiro Kubota, Hirohito Sawahata, Shota Yamagiwa, Minako Matsuo, Tadahiro Iimura, Hajime Tei, Makoto Ishida, Takeshi Kawano
Publikováno v:
FEBS open bio. 12(4)
Genetic modification to restore cell functions in the brain can be performed through the delivery of biomolecules in a minimally invasive manner into live neuronal cells within brain tissues. However, conventional nanoscale needles are too short (len
Autor:
Makoto Ishida, Shota Yamagiwa, Takeshi Kawano, Yoshihiro Kubota, Minako Matsuo, Akihiro Goryu, Rika Numano, Hirohito Sawahata
Publikováno v:
2018 IEEE Micro Electro Mechanical Systems (MEMS).
Nanoscale geometric devices, which penetrate cells, offer numerous intracellular applications. DNA injection into a cell has potential to genetically alter the function of living brain cells. However, nanowire (or nanotube) — based conventional int
Publikováno v:
AIP Conference Proceedings.
The biochemical, physiological and behavioral processes are under the control of internal clocks with the period of approximately 24 hr, circadian rhythms. The expression of clock gene Period1 (Per1) oscillates autonomously in cells and is induced im