Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Autor: Minako Imamura, Atsushi Takahashi, Toshimasa Yamauchi, Kazuo Hara, Kazuki Yasuda, Niels Grarup, Wei Zhao, Xu Wang, Alicia Huerta-Chagoya, Cheng Hu, Sanghoon Moon, Jirong Long, Soo Heon Kwak, Asif Rasheed, Richa Saxena, Ronald C. W. Ma, Yukinori Okada, Minoru Iwata, Jun Hosoe, Nobuhiro Shojima, Minaka Iwasaki, Hayato Fujita, Ken Suzuki, John Danesh, Torben Jørgensen, Marit E. Jørgensen, Daniel R. Witte, Ivan Brandslund, Cramer Christensen, Torben Hansen, Josep M. Mercader, Jason Flannick, Hortensia Moreno-Macías, Noël P. Burtt, Rong Zhang, Young Jin Kim, Wei Zheng, Jai Rup Singh, Claudia H. T. Tam, Hiroshi Hirose, Hiroshi Maegawa, Chikako Ito, Kohei Kaku, Hirotaka Watada, Yasushi Tanaka, Kazuyuki Tobe, Ryuzo Kawamori, Michiaki Kubo, Yoon Shin Cho, Juliana C. N. Chan, Dharambir Sanghera, Philippe Frossard, Kyong Soo Park, Xiao-Ou Shu, Bong-Jo Kim, Jose C. Florez, Teresa Tusié-Luna, Weiping Jia, E Shyong Tai, Oluf Pedersen, Danish Saleheen, Shiro Maeda, Takashi Kadowaki

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

Here, Imamuraet al. conduct meta-analysis of genome-wide association studies to identify novel susceptibility loci for type 2 diabetes (T2D) in the Japanese population. By doing so, this study shows that both ethnicity-specific and ethnically-shared

Externí odkaz: https://doaj.org/article/389e503091f247e28b5236cff3387f83

Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes

Autor: Danish Saleheen, John Danesh, Claudia H. T. Tam, Josep M. Mercader, Torben Hansen, Sanghoon Moon, Noël P. Burtt, Ivan Brandslund, Rong Zhang, Minaka Iwasaki, Kazuyuki Tobe, Takashi Kadowaki, Daniel R. Witte, Young-Jin Kim, Hiroshi Hirose, Bong-Jo Kim, Jai Rup Singh, Jason Flannick, Hortensia Moreno-Macías, Jun Hosoe, Minako Imamura, Torben Jørgensen, Kazuki Yasuda, Toshimasa Yamauchi, Jose C. Florez, Hirotaka Watada, Richa Saxena, Teresa Tusié-Luna, Atsushi Takahashi, Cramer Christensen, Kyong Soo Park, Juliana C.N. Chan, Niels Grarup, Cheng Hu, Ryuzo Kawamori, Yasushi Tanaka, Asif Rasheed, Kazuo Hara, Kohei Kaku, Ronald C.W. Ma, Jirong Long, Yoon Shin Cho, Dharambir K. Sanghera, E. Shyong Tai, Soo Heon Kwak, Xu Wang, Chikako Ito, Alicia Huerta-Chagoya, Yukinori Okada, Wei Zheng, Wei Zhao, Shiro Maeda, Hayato Fujita, Ken Suzuki, Xiao-Ou Shu, Weiping Jia, Philippe M. Frossard, Oluf Pedersen, Marit E. Jørgensen, Hiroshi Maegawa, Michiaki Kubo, Nobuhiro Shojima, Minoru Iwata

Publikováno v: Imamura, M, Takahashi, A, Yamauchi, T, Hara, K, Yasuda, K, Grarup, N, Zhao, W, Wang, X, Huerta-Chagoya, A, Hu, C, Moon, S, Long, J, Kwak, S H, Rasheed, A, Saxena, R, Ma, R C W, Okada, Y, Iwata, M, Hosoe, J, Shojima, N, Iwasaki, M, Fujita, H, Suzuki, K, Danesh, J, Jørgensen, T, Jørgensen, M E, Witte, D R, Brandslund, I, Christensen, C, Hansen, T, Mercader, J M, Flannick, J, Moreno-Macías, H, Burtt, N P, Zhang, R, Kim, Y J, Zheng, W, Singh, J R, Tam, C H T, Hirose, H, Maegawa, H, Ito, C, Kaku, K, Watada, H, Tanaka, Y, Tobe, K, Kawamori, R, Kubo, M, Cho, Y S, Chan, J C N, Sanghera, D, Frossard, P, Park, K S, Shu, X-O, Kim, B-J, Florez, J C, Tusié-Luna, T, Jia, W, Tai, E S, Pedersen, O, Saleheen, D, Maeda, S & Kadowaki, T 2016, ' Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes ', Nature Communications, vol. 7, 10531 . https://doi.org/10.1038/ncomms10531
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Nature Communications

Genome-wide association studies (GWAS) have identified more than 80 susceptibility loci for type 2 diabetes (T2D), but most of its heritability still remains to be elucidated. In this study, we conducted a meta-analysis of GWAS for T2D in the Japanes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1986a8576f0667d4327c1d586c190c
https://vbn.aau.dk/da/publications/1406f2ba-ef7b-4a42-93db-b0232e172e40