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Akademický článek

The Ring Transformation of 3-Methyl-5-nitropyrimidin-4(3H)-one

Autor: Masahiro Ariga, Yasuo Tohda, Kazushige Hori, Mina Tamura, Nagatoshi Nishiwaki

Publikováno v: Molecules, Vol 8, Iss 6, Pp 500-504 (2003)

3-Methyl-5-nitropyrimidin-4(3H)-one readily reacts with carbonyl compounds to produce three kinds of ring transformations. The nitropyrimidinone behaves as the synthetic equivalent of activated diformylamine affording 3,5-difunctionalized 4-pyridones

Externí odkaz: https://doaj.org/article/20c63d3908b443f0a22546adcc8db941

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Sapropterin for phenylketonuria: A Japanese post-marketing surveillance study

Autor: Shuichi Chikada, Kento Wada, Mina Tamura, Yasuyuki Kakurai, Shizuka Seki

Publikováno v: Pediatrics international : official journal of the Japan Pediatric Society. 64(1)

The aim of this study was to assess the long-term safety and efficacy of sapropterin in a real-world setting in Japanese patients with tetrahydrobiopterin (BH4)-responsive phenylketonuria.This post-marketing surveillance study enrolled all of the pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba55f2d9b2ad7b31c9d5e0fa54e34a35
https://pubmed.ncbi.nlm.nih.gov/34331785

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Relationship between the Arctic oscillation and surface air temperature in multi-decadal time-scale

Autor: Hiroshi Tanaka, Mina Tamura

Publikováno v: Polar Science. 10(3):199-209

In this study, a simple energy balance model (EBM) was integrated in time, considering a hypothetical long-term variability in ice-albedo feedback mimicking the observed multi-decadal temperature variability. A natural variability was superimposed on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d660d16783607625a7328afda737eae0

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Improved Dimerization of Diethyl Acetonedicarboxylate Leading to Polyfunctionalized Phenol

Autor: Nagatoshi Nishiwaki, Mina Tamura, Hajime Yagi, Makoto Matsumoto, Takanobu Shinkawa, Masahiro Ariga

Publikováno v: Journal of Oleo Science. 54:461-464

When a pyridine solution of sodium enolate of diethyl acetonedicarboxylate was heated in the presence of p-nitrophenol, the dimerization readily proceeded under mild conditions to give polyfunctionalized phenol, ethyl {2,4-bis(ethoxycarbonyl)-3,5-dih

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3de1496920c845cb370b4730adcdd0d0
https://doi.org/10.5650/jos.54.461

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The Ring Transformation of 3-Methyl-5-nitropyrimidin-4(3H)-one

Autor: Kazushige Hori, Nagatoshi Nishiwaki, Masahiro Ariga, Mina Tamura, Yasuo Tohda

Publikováno v: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 8, Iss 6, Pp 500-504 (2003)
Molecules; Volume 8; Issue 6; Pages: 500-504

3-Methyl-5-nitropyrimidin-4(3 H )-one readily reacts with carbonyl compounds to produce three kinds of ring transformations. The nitropyrimidinone behaves as the synthetic equivalent of activated diformylamine affording 3,5-difunctionalized 4-pyridon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03ccd416f75e7562ff8a86135c25ffe
http://europepmc.org/articles/PMC6146944

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A NOVEL RING TRANSFORMATION OF NITROPYRIMIDINONE LEADING TO POLYFUNCTIONALIZED PYRIDONES

Autor: Nagatoshi Nishiwaki, Mina Tamura, Masahiro Ariga, Kazuo Matsushima, Hiromi Morimura

Publikováno v: Heterocycles. 61:19-22

Polyfunctionalized 2-pyridones are readily prepared by the ring transformation using 3-methyl-5-nitropyrimidin-4(3H)-one with active methylene compounds in the presence of piperidine.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c969449409d68cea30355c05fbaa3c32
http://ir.lib.osaka-kyoiku.ac.jp/dspace/handle/123456789/568

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Unusual ring transformation of N-hydroxy-3,5-dinitro-4-pyridone affording a polyfunctionalized pyrrole

Autor: Mina Tamura, Kazushige Hori, Noriko Asaka, Nagatoshi Nishiwaki, Kazuo Matsushima, Masahiro Ariga, Yasuo Tohda

Publikováno v: ARKIVOC, Vol 2002, Iss 10, Pp 34-39 (2002)

Polyfunctionalized pyrrole 6 is synthesized in the ring transformation of N-hydroxy-3,5-dinitro4-pyridone 4 with enolate 2 derived from diethyl 3-oxogulutarate. The present reaction proceeds with C-N transfer from 4 to 2, which is hitherto unknown ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e563b52195a4b15c9ca30d9d0a91dd58
https://www.arkat-usa.org/arkivoc-journal/browse-arkivoc/ark.5550190.0003.a05

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Novel functionalization of 1-methyl-2-quinolone; dimerization and denitration of trinitroquinolone

Autor: Kazushige Hori, Midori Sakashita, Yasuo Tohda, Mina Tamura, Mayumi Azuma, Masahiro Ariga, Noriko Asaka, Nagatoshi Nishiwaki, Chitose Tanaka

Publikováno v: Tetrahedron. 58:473-478

New methods for functionalization of 1-methyl-2-quinolone (MeQone) skeleton are provided. The reaction of 1-methyl-3,6,8-trinitro-2-quinolone (TNQ) with amines affords quinolone dimer 1 and 6,8-dinitroquinolone (6,8-DNQ). Dimerization predominantly p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca59a11b05972a5a92ae48789e4a8a98
https://doi.org/10.1016/s0040-4020(01)01169-3

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