Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mina Mousavian"'
Autor:
Mina Mousavian, Seyed Jamal Alavi, Raheleh Rahbarian, Majid Rajabian, Hossein Orafai, Hamid Sadeghian
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 23, Iss 8, Pp 984-989 (2020)
Objective(s): Allylbenzenes have been recently developed as inhibitors of lipoxygenases. They decrease peroxidation activity via mimicking 1,4-unsaturated bonds of fatty acids by their allyl portion. We designed and synthesized new derivatives of all
Externí odkaz:
https://doaj.org/article/01d8868b679846d2831fdbbe3f923007
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171789 (2017)
Allyloxy, Isopentenyloxy, geranyloxy and farnesyloxy derivatives of 3-carboxycoumarin, at position 5, 6, 7, and 8, were synthesized and their inhibitory potency against human 15-lipoxygenase-1 (human 15-LOX-1) were determined. Among the synthetic cou
Externí odkaz:
https://doaj.org/article/c6fb89fba3444332b7da303be8235f33
Publikováno v:
Prostaglandinsother lipid mediators. 148
Lipoxygenases (LOXs) are enzymes which found in organisms that catalyze the peroxidation of polyunsaturated fatty acids (Arachidonic acid, Linoleic acid). The key role of the mentioned enzymes and their metabolites in formation of sensitivities, infl
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171789 (2017)
PLoS ONE
PLoS ONE
Allyloxy, Isopentenyloxy, geranyloxy and farnesyloxy derivatives of 3-carboxycoumarin, at position 5, 6, 7, and 8, were synthesized and their inhibitory potency against human 15-lipoxygenase-1 (human 15-LOX-1) were determined. Among the synthetic cou
Publikováno v:
Medicinal Chemistry Research. 22:5036-5043
A series of 2-substituted 4-n-propyl pyrimido[4,5-b][1,4]benzothiazines were synthesized, and evaluated as soybean 15-lipoxygenase (SLO) inhibitors. Among the synthesized compounds, 2-(4-methyl piperazinyl) analog showed the best SLO inhibition activ
Autor:
Mina Mousavian, Hamid Sadeghian, Atena Jabbari, Mehdi Bakavoli, Alireza Salimi, Seyed Mohammad Seyedi
Publikováno v:
Chemical biologydrug design. 88(3)
15-lipo-oxygenases are one of the iron-containing proteins capable of performing peroxidation of unsaturated fatty acids in animals and plants. The critical role of enzymes in the formation of inflammations, sensitivities, and some cancers has been d