Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mina Akaiwa"'
Publikováno v:
Histopathology. 38:368-375
Aims: Hodgkin's disease (HD) is characterized by the presence of Hodgkin and Reed–Sternberg (H–RS) cells against a hyperplastic background of reactive cells such as lymphocytes, histiocytes, plasma cells, eosinophils, neutrophils, and stromal cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4dc91ec2c993a50400d42a68973704
https://doi.org/10.1046/j.1365-2559.2001.01083.x
https://doi.org/10.1046/j.1365-2559.2001.01083.x
Autor:
Rie Sugimoto, Mina Akaiwa, Yojiro Arinobu, Kazuhiko Arima, Takeshi Otsuka, Naotaka Hamasaki, Kenji Izuhara
Publikováno v:
Biochemical and Biophysical Research Communications. 277:317-324
Signal transducer and activation of transcription (STAT)6 has a central role in the signal transduction of interleukin (IL)-4 and IL-13. It has recently been revealed that STAT3 is also involved. STAT6 and STAT3 are expressed ubiquitously; however, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e721c3df4bb777d99de82bc661a06c61
https://doi.org/10.1006/bbrc.2000.3674
https://doi.org/10.1006/bbrc.2000.3674
Autor:
Yojiro Arinobu, Tetsuji Yamashita, S. Kruse, Tadao Enomoto, Bin Yu, Naotaka Hamasaki, Koichi Ohshima, Chaker N. Adra, Fumihiko Kurimoto, M. Kawai, Hiroshi Inoue, Klaus A. Deichmann, Kazuhiko Arima, R. T. Kreomer, Sandra Braun, Mina Akaiwa, X. Q. Mao, S. Sasaki, Y. Dake, S. Shimazu, Nobukazu Tomichi, T. Shirakawa, Rie Sugimoto, Mark H. Roberts, Kohei Yamauchi, Yoshito Abe, M. Kitaichi, Kenji Izuhara, Peisong Gao, Julian M. Hopkin, Andrea Heinzmann, R. Umeshita
Publikováno v:
Scopus-Elsevier
Asthma and atopy show epidemiological association and are biologically linked by T-helper type 2 (T(h)2) cytokine-driven inflammatory mechanisms. IL-4 operates through the IL-4 receptor (IL-4R, a heterodimer of IL-4Ralpha and either gammac or IL-13Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41694a04b2ca25f7fa210c9d8520835c
https://doi.org/10.1093/hmg/9.4.549
https://doi.org/10.1093/hmg/9.4.549
Autor:
Fumio Nagumo, Noriko Yuyama, Donna E. Davies, Kazuhiko Arima, Yuhei Hamasaki, Naotaka Hamasaki, Tetsuji Yamashita, Yuji Sugita, Yoshinori Suminami, Ivan M. Richards, Miyako Maeda, Koichi Ohshima, Mina Akaiwa, Ning Lu Yoshida, Hiroshi Kato, Jutaro Tadano, Kenji Izuhara, Mitsuhiko Sugimachi, Anita Pandit, Yumiko Kamogawa, Ann Berger, Fumio Kishi, Ken-ichi Arai, Shoichiro Miyatake, Keiko Matsui, Steven L. Roberds, James L. Lordan, Stephen T. Holgate
Publikováno v:
Cytokine. 19(6)
Bronchial asthma is a complex disease characterized by airway inflammation involving interleukin (IL)-4 and IL-13. We have applied microarray analyses to human bronchial epithelial cultures to probe for genes regulated by these cytokines and have ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a722054c1f2e9799b6f97a29863f1e25
https://pubmed.ncbi.nlm.nih.gov/12421571
https://pubmed.ncbi.nlm.nih.gov/12421571
Autor:
Kenji Izuhara, Yuji Sugita, Mina Akaiwa, Ning Lu Yoshida, Keiko Matsui, Miyako Maeda, Noriko Yuyama
Publikováno v:
Gene. 293(1-2)
Cathepsin C/dipeptidyl-peptidase I is a papain-like lysosomal cysteine proteinase implicated in the processing of various proenzymes to their active forms. In this study, we identified an alternative splicing variant of cathepsin C in both human and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eeb2a9ad52b02b4db966ed72cb9c904
https://pubmed.ncbi.nlm.nih.gov/12137938
https://pubmed.ncbi.nlm.nih.gov/12137938
Autor:
Tetsuji Yamashita, Shin-ichiro Shimazu, Xiao-Quan Mao, Ritsuko Umeshita-Suyama, Mohamad H. Sayegh, Mina Akaiwa, Julian M. Hopkin, Scott R. Brodeur, Yasuhisa Sakata, Raj K. Puri, Kazuhiko Arima, Naoto Sugawara, Yoshio Dake, Raif S. Geha, Naotaka Hamasaki, Chaker N. Adra, Kenji Izuhara, T. Shirakawa, Tadao Enomoto
Publikováno v:
The Journal of allergy and clinical immunology. 109(6)
Background: A substantial body of evidence exists to support the pivotal role of IL-13 in the pathogenesis of bronchial asthma. We recently found that a variant of the IL13 gene (Arg110Gln) is genetically associated with bronchial asthma, which is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094c7d347f293d8702adfda1fbebe9fe
https://pubmed.ncbi.nlm.nih.gov/12063528
https://pubmed.ncbi.nlm.nih.gov/12063528
Autor:
Mina Akaiwa, Bin Yu, Kazuhiko Arima, Nobuhisa Terada, Kenji Izuhara, Naotaka Hamasaki, Koichi Ohshima, Hideoki Ogawa, Tetsuya Koga, Hajime Suto, Hirohisa Saito, Masutaka Furue, Sho Matsushita, Ritsuko Umeshita-Suyama
Publikováno v:
Cytokine. 13(2)
Although the functional roles of interleukin (IL-)13 in haematopoietic cells are well investigated, those in non-haematopoietic cells remain to be addressed. IL-13 exerts its actions by binding to the IL-13 receptor (IL-13R) on target cells, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c323b03436d36386bcda35449c688e6
https://pubmed.ncbi.nlm.nih.gov/11145846
https://pubmed.ncbi.nlm.nih.gov/11145846
Autor:
Julian M. Hopkin, Kenji Izuhara, Ritsuko Umeshita-Suyama, Kazuhiko Arima, Naotaka Hamasaki, Mina Akaiwa, Klaus A. Deichmann, T. Shirakawa
Publikováno v:
Inflammation ISBN: 9789048158522
The prevalence of allergic disease has dramatically increased in recent decades, especially in urban and industrialized areas. Allergic diseases are disorders of the immune system, the results of complex interactions among various genetic and environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1501cd3dbc2abc92b11b226406066f5d
https://doi.org/10.1007/978-94-015-9702-9_10
https://doi.org/10.1007/978-94-015-9702-9_10
Autor:
Morimasa Wada, Mina Akaiwa, Ritsuko Umeshita-Suyama, Bin Yu, Kenji Izuhara, Koichi Nakajima, Kazuhiko Arima, Rie Sugimoto, Naotaka Hamasaki, Michihiko Kuwano
Publikováno v:
Scopus-Elsevier
IL-4 and IL-13 are pleiotropic cytokines whose biological activities overlap with each other. IL-13 receptor alpha chain 1 (IL-13R alpha 1) is necessary for binding to IL-13, and the heterodimer composed of IL-13R alpha 1 and IL-4R alpha chain transd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d115d5a71164720eb1b99bd6aa40e335
https://pubmed.ncbi.nlm.nih.gov/11058569
https://pubmed.ncbi.nlm.nih.gov/11058569
Autor:
Mina Akaiwa, Kenji Izuhara, Toru Iwaki, Satoshi O. Suzuki, Rie Sugimoto, Yoshiaki Yae, Naotaka Hamasaki
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 47(6)
Hakata antigen was first reported as a serum protein that reacted with an autoantibody from patients with systemic lupus erythematosus. Recently, it has been found that Hakata antigen is a new member of the ficolin/opsonin p35 family, which is a dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37138a3c724ceb97d3cbc4c5273fae9e
https://pubmed.ncbi.nlm.nih.gov/10330454
https://pubmed.ncbi.nlm.nih.gov/10330454