Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mina Dilmeghani Seran"'
Autor:
Mina Dilmeghani Seran, Jacqueline E. Milne, John T. Colyer, Oliver R. Thiel, Thomas Storz, Robert D. Larsen, Jerry A. Murry
Publikováno v:
The Journal of Organic Chemistry. 76:9519-9524
A new convenient and scalable synthesis of phenylacetic acids has been developed via the iodide catalyzed reduction of mandelic acids. The procedure relies on in situ generation of hydroiodic acid from catalytic sodium iodide, employing phosphorus ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdeedf510fb529f1fbe28ae2a37edd71
https://doi.org/10.1021/jo2018087
https://doi.org/10.1021/jo2018087
Autor:
Oliver R. Thiel, Margaret M. Faul, Tracy Bostick, Robert D. Larsen, Tony King, Charles Bernard, Mina Dilmeghani-Seran
Publikováno v:
The Journal of Organic Chemistry. 73:3508-3515
Small molecule TRPV1 antagonists have been a recent focus in the search for pain treatment agents. We herein describe a practical and scalable synthesis of AMG 628 (1), a bis-substituted pyrimidine derivative that was identified as a highly efficacio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a84f4eec45466c2b2c3ef5166a14423
https://doi.org/10.1021/jo8002216
https://doi.org/10.1021/jo8002216
Autor:
Mina Dilmeghani Seran, Van Luu, Helming Tan, Kyung H. Gahm, Rob Larsen, Janet Cheetham, Paul J. Reider, Tracy Bostick, Mike Martinelli, Maggie Reed, Tony King, David J. Semin
Publikováno v:
Organic Process Research & Development. 12:58-65
Trituration and crystallization are essential techniques for purification of intermediates and drug substances in pharmaceutical process development. Traditionally, identifying the optimal solvent conditions for impurity rejection adopts an empirical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb368b6dc8e2e03f5760e24a2058317
https://doi.org/10.1021/op700144e
https://doi.org/10.1021/op700144e
Autor:
Mina Dilmeghani Seran, Robert D. Larsen, Jerry A. Murry, Jacqueline E. Milne, Thomas Storz, Oliver R. Thiel, John T. Colyer
Publikováno v:
ChemInform. 43
Treatment of mandelic and phenylglyoxylic acids with NaI/H3PO4/MesOH allows a new and efficient access to phenylacetic acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ea8b761ded03e96995b80fb7b46a78c
https://doi.org/10.1002/chin.201212045
https://doi.org/10.1002/chin.201212045
Autor:
Helming Tan, Maggie Reed, Kyung H. Gahm, Tony King, Mina Dilmeghani Seran, Tracy Bostick, Van Luu, David Semin, Janet Cheetham, Rob Larsen, Mike Martinelli, Paul Reider
Publikováno v:
Organic Process Research & Development; Dec2007, Vol. 12 Issue 1, p58-65, 8p