Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Min-Ke He"'
Autor:
Dong-sheng Wen, Li-chang Huang, Xiao-yun Bu, Min-ke He, Zhi-cheng Lai, Ze-feng Du, Ye-xing Huang, Anna Kan, Ming Shi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-12 (2023)
Abstract Altered DNA methylation is a crucial epigenetic event in hepatocellular carcinoma (HCC) development and progression. Through methylation-transcriptomic analysis, we identified a set of sixty potential DNA methylation-based epidriver genes. I
Externí odkaz:
https://doaj.org/article/df6c007c71364c2b88ae8c131f2e85ca
Autor:
Yu-Jie Xu, Zhi-Cheng Lai, Anna Kan, Hui Liu, Yu Huang, Yue-Yuan Lai, Jie-Feng Weng, Zhao-Feng Wu, Ming Shi, Wei-Li Gu, Shuai Zhang, Min-Ke He
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 243 (2024)
Background: The tumour mutation burden (TMB) is a valuable indicator of the accumulation of somatic mutations, and is thought to be associated with the biological behaviour and prognosis of tumours. However, the related genetic mechanism for these as
Externí odkaz:
https://doaj.org/article/4f3c91e9185b4029aa181da4f194be9c
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-14 (2021)
Abstract Background The accumulation of single nucleotide variants (SNVs) and the emergence of neoantigens can affect tumour proliferation and the immune microenvironment. However, the SNV-related immune microenvironment characteristics and key genes
Externí odkaz:
https://doaj.org/article/1018776c018c4b11b068acfac8ee2848
Autor:
Yu-Jie Xu MD, Zhi-Cheng Lai MD, Min-Ke He MD, Xiao-Yun Bu MD, Huan-Wei Chen MD, Yuan-Min Zhou MD, Li Xu MD, Wei Wei MD, Yao-Jun Zhang MD, Min-Shan Chen MD, Rong-Ping Guo MD, Ming Shi MD, Qi-Jiong Li MD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 20 (2021)
Purpose: Immunotherapy combined with chemotherapy have synergistic effects in multiple malignancies. We aimed to compare the efficacy and safety of toripalimab plus hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin, fluorouracil, and leuco
Externí odkaz:
https://doaj.org/article/cbb3d7bec5794c30ba745d6d3ade94bd
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Hepatocellular carcinoma (HCC) is one of the most fatal cancers, and its molecular basis needs to be delineated to identify biomarkers for its potential treatment. The purpose of this study was to identify a novel gene, nucleosome
Externí odkaz:
https://doaj.org/article/d96cf2515ef44c6985e3fcaa45491014
Autor:
Run-Bin Liang, Yang Zhao, Min-Ke He, Dong-Sheng Wen, Xiao-Yun Bu, Ye-Xing Huang, Zhi-Cheng Lai, Yu-Jie Xu, Anna Kan, Wei Wei, Yao-Jun Zhang, Min-Shan Chen, Rong-Ping Guo, Qi-Jiong Li, Ming Shi
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeOur previous study showed that hepatic arterial infusion chemotherapy (HAIC) using oxaliplatin, fluorouracil, and leucovorin (FOLFOX) plus sorafenib provided a significant survival benefit over sorafenib for advanced hepatocellular carcinoma.
Externí odkaz:
https://doaj.org/article/c299e980c64c4d42bb94db2d7aa2fe02
Autor:
Min-Ke He, Run-Bin Liang, Yang Zhao, Yu-Jie Xu, Huan-Wei Chen, Yuan-Min Zhou, Zhi-Cheng Lai, Li Xu, Wei Wei, Yao-Jun Zhang, Min-Shan Chen, Rong-Ping Guo, Qi-Jiong Li, Ming Shi
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Lenvatinib is the first-line treatment for advanced hepatocellular carcinoma, but prognosis is still unsatisfactory. Recently, hepatic arterial infusion chemotherapy (HAIC), and immune checkpoint inhibitors showed promising results for ad
Externí odkaz:
https://doaj.org/article/4d8d01bd04af49ef8dd01017c4f1c005
Autor:
Hai‐Long Chen, Han‐Yue OuYang, Yong Le, Peng Jiang, Hui Tang, Zi‐Shan Yu, Min‐Ke He, Yun‐Qiang Tang, Ming Shi
Publikováno v:
Cancer Medicine, Vol 7, Iss 11, Pp 5339-5350 (2018)
Abstract The tumor microenvironment is a key determinant of cancer cell biology. The microenvironment is a complex mixture of tumor cells, stromal cells, and proteins, extracellular matrix, oxygen tension, and pH levels surrounding the cells that reg
Externí odkaz:
https://doaj.org/article/dd16f47702354ea1b2fba1c4fe9ab4de
Publikováno v:
Chinese Journal of Cancer, Vol 36, Iss 1, Pp 1-8 (2017)
Abstract Background Transarterial chemoembolization (TACE) is recommended as the standard care for unresectable hepatocellular carcinoma (HCC) at Barcelona Clinic Liver Cancer (BCLC) stage A–B. However, the efficacy of TACE on large (≥ 10 cm) sta
Externí odkaz:
https://doaj.org/article/1d9d2767f17848f78b0453eee7101d3e
Autor:
Qi-Jiong Li, Huan-Wei Chen, Min-Ke He, Wan-Qiang Fang, Ying Guo, Ming Shi, Wei Wei, Yuan-Min Zhou, Minshan Chen, Yaojun Zhang, Li Xu, Rong Ping Guo
Publikováno v:
Journal of Clinical Oncology. 40:150-160
PURPOSE In a previous phase II trial, hepatic arterial infusion chemotherapy (HAIC) with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX) yielded higher treatment responses than transarterial chemoembolization (TACE) in large unresectabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2905097be14a20671dee704a565d74f8
https://doi.org/10.1200/jco.21.00608
https://doi.org/10.1200/jco.21.00608