Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Min-Gul Kim"'
Autor:
Heejae Won, Eunwoo Kim, Jihye Chae, Hyejung Lee, Joo‐Youn Cho, In‐Jin Jang, Jae‐Yong Chung, Min‐Gul Kim, SeungHwan Lee
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 5, Pp n/a-n/a (2024)
Abstract Fexuprazan, a novel potassium‐competitive acid blocker, is expected to be used for the prevention of nonsteroidal anti‐inflammatory drugs (NSAIDs) induced ulcer. This study aimed to evaluate pharmacokinetic (PK) interactions between fexu
Externí odkaz:
https://doaj.org/article/475024b57dc74454a209823d6aa006ec
Autor:
You Mi Hong, Jaewoong Lee, Dong Hyu Cho, Jung Hun Jeon, Jihoon Kang, Min-Gul Kim, Semin Lee, Jin Kyu Kim
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Preterm birth prediction is essential for improving neonatal outcomes. While many machine learning techniques have been applied to predict preterm birth using health records, inflammatory markers, and vaginal microbiome data, the role of pre
Externí odkaz:
https://doaj.org/article/f35ef18a5c604a188f63e0dec650eb93
Autor:
Ki Young Huh, Woo Kyung Chung, Jiyeon Park, SeungHwan Lee, Min‐Gul Kim, Jaeseong Oh, Kyung‐Sang Yu
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 11, Pp 2177-2188 (2023)
Abstract Decentralized clinical trials (DCTs) leverage digital technologies to reduce dependency on study sites and intermediaries. DCT should be balanced with accessibility and data reliability while meeting regulatory requirements. Here, we conduct
Externí odkaz:
https://doaj.org/article/bb12b2c524c84c39bbedd1774c272e90
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Appropriate storage of fecal samples is a critical step for unbiased analysis in human microbiome studies. The purpose of this study was to evaluate the stability of the fecal microbial community for up to 18 months. Ten healthy volunteers p
Externí odkaz:
https://doaj.org/article/3220420a73ab414e9a889d2888c50a66
Autor:
Ki Young Huh, Seol Ju Moon, Sang‐un Jeong, Min‐Ji Kim, Wooseok Yang, Myeonggyu Jeong, Min‐Gul Kim, SeungHwan Lee
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1257-1268 (2022)
Abstract Blockchain is a novel data architecture characterized by a chronological sequence of blocks in a decentralized manner. We aimed to evaluate the real‐world feasibility of a blockchain‐based dynamic consent platform (METORY) in a decentral
Externí odkaz:
https://doaj.org/article/ab23b978149d4c1a9a4fa2dc0c0de73a
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
BackgroundProton pump inhibitors (PPIs) are acid suppressants that are frequently prescribed in many countries to reduce heartburn. A potassium-competitive acid blocker (P-CAB; tegoprazan) was launched relatively recently that also inhibits gastric a
Externí odkaz:
https://doaj.org/article/97794ad18211474eb4ce66a58190a64f
Autor:
Kyung‐Sang Yu, In‐Jin Jang, Hyeong‐Seok Lim, Jang Hee Hong, Min‐Gul Kim, Min Kyu Park, Doo‐Yeoun Cho, Min Soo Park, Jae Yong Chung, Jong‐Lyul Ghim, SeungHwan Lee, Seok Kyu Yoon, In Sun Kwon, Sang Joon Lee, Sung Hyun Kim, Yun Ju Bae, Jung Bin Cha, Daniel E. Furst, Edward Keystone, Jonathan Kay
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 4, Pp 1280-1291 (2021)
Abstract This study aimed to demonstrate pharmacokinetic (PK) equivalence of a single dose of the proposed adalimumab biosimilar CT‐P17 to United States‐licensed adalimumab (US‐adalimumab) and European Union‐approved adalimumab (EU‐adalimum
Externí odkaz:
https://doaj.org/article/7d507bd001904a1aa34884f6d604a326
Autor:
Ki Young Huh, Sang-un Jeong, Seol Ju Moon, Min-Ji Kim, Wooseok Yang, Myeonggyu Jeong, Ildae Song, Yong-Geun Kwak, SeungHwan Lee, Min-Gul Kim
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The recent advent of the dynamic consent concept intensified the data integrity issue in clinical trials. Incorporating blockchain technology into a dynamic consent platform can be a feasible solution. Due to various clinical trial settings, a demand
Externí odkaz:
https://doaj.org/article/5f62c9bdfe5446eaae8fcd947daf737b
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 360 (2023)
Tegoprazan is a novel potassium-competitive acid blocker. This study investigated the effect of drug–drug interaction on the pharmacokinetics and pharmacodynamics of tegoprazan co-administered with amoxicillin and clarithromycin, the first-line the
Externí odkaz:
https://doaj.org/article/64e30ad15be94efba908135796e99bea
Autor:
Hyeon-Cheol Jeong, Min-Gul Kim, Zhuodu Wei, Kyeong-Ryoon Lee, Jaehyeok Lee, Im-Sook Song, Kwang-Hee Shin
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1298 (2022)
A physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for tegoprazan and its major metabolite M1 was developed to predict PK and PD profiles under various scenarios. The PBPK model for tegoprazan and M1 was developed and predicted u
Externí odkaz:
https://doaj.org/article/c63b3f3b1dc947cab71536f019664ccb