Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Min-Fen Hsu"'
Oncogenic KRAS, Mucin 4, and Activin A‐Mediated Fibroblast Activation Cooperate for PanIN Initiation
Autor:
Chun‐Mei Hu, Chien‐Chang Huang, Min‐Fen Hsu, Hung‐Jen Chien, Pei‐Jung Wu, Yi‐Ing Chen, Yung‐Ming Jeng, Shiue‐Cheng Tang, Mei‐Hsin Chung, Chia‐Ning Shen, Ming‐Chu Chang, Yu‐Ting Chang, Yu‐Wen Tien, Wen‐Hwa Lee
Publikováno v:
Advanced Science, Vol 10, Iss 36, Pp n/a-n/a (2023)
Abstract Over 90% of patients with pancreatic ductal adenocarcinoma (PDAC) have oncogenic KRAS mutations. Nevertheless, mutated KRAS alone is insufficient to initiate pancreatic intraepithelial neoplasia (PanIN), the precursor of PDAC. The identities
Externí odkaz:
https://doaj.org/article/4a0e87c67012457eb7ccce5aa913ffd6
Autor:
Yi-Ing Chen, Chin-Chun Chang, Min-Fen Hsu, Yung-Ming Jeng, Yu-Wen Tien, Ming-Chu Chang, Yu-Ting Chang, Chun-Mei Hu, Wen-Hwa Lee
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Direct contact between tumour cells and fibroblasts influences tumour cell behaviour. Here the authors show that pancreatic cancer cells and fibroblasts directly interact via homophilic ATP1A1 binding, which induces fibroblasts to secrete activin A t
Externí odkaz:
https://doaj.org/article/0ef09420616e4351be36b283dc768cbd
Publikováno v:
International Journal of Clinical Practice, Vol 2022 (2022)
Background. Physical activity (PA) is a basic and initiative conservative management for people with knee osteoarthritis (KOA). This study aimed to explore the potential indicators of PA levels in people with KOA. Methods. We designed a cross-section
Externí odkaz:
https://doaj.org/article/7577b9c40f454a9d8782d6e05d7e5544
High glucose induces bone marrow-derived mesenchymal stem cell senescence by upregulating autophagy.
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126537 (2015)
Hyperglycemia was reported to cause bone marrow hematopoietic niche dysfunction, and high glucose (HG) in the cultured medium induces MSC senescence. The underlying mechanism is unclear. Here, we investigated the role of HG-induced autophagy in bone-
Externí odkaz:
https://doaj.org/article/ac6c6afb6f5040218fc1bdee4b4b9281
Autor:
Min-Fen Hsu, 許民芬
100
It has been reported that abnormal Wnt/β-catenin signaling is associated with hematological malignancies. Wnt/β-catenin signaling is involved in cell proliferation, differentiation, survival and apoptosis. In previous study, we have report
It has been reported that abnormal Wnt/β-catenin signaling is associated with hematological malignancies. Wnt/β-catenin signaling is involved in cell proliferation, differentiation, survival and apoptosis. In previous study, we have report
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/76974775277389553967
Autor:
Min-fen Hsu, 徐敏芬
94
There are two purposes in this study. The first purpose is to compare differences in educational models, which are used to teach caregivers and patients themselves to care for skin lesions in the feet related to diabetes mellitus. The second
There are two purposes in this study. The first purpose is to compare differences in educational models, which are used to teach caregivers and patients themselves to care for skin lesions in the feet related to diabetes mellitus. The second
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/59169913707117885505
Autor:
Zheng-Yu Lin, Kun-Ching Cheng, Huey-Jen Su, Chi-I Chang, Jue-Liang Hsu, Min-fen Hsu, Mei-Chin Lu, Yun-Sheng Lin
Publikováno v:
Chemistry of Natural Compounds. 58:659-668
Autor:
Yi-Ing Chen, Chin-Chun Chang, Min-Fen Hsu, Yung-Ming Jeng, Yu-Wen Tien, Ming-Chu Chang, Yu-Ting Chang, Chun-Mei Hu, Wen-Hwa Lee
Publikováno v:
Nature communications. 13(1)
Tumor cells with diverse phenotypes and biological behaviors are influenced by stromal cells through secretory factors or direct cell-cell contact. Pancreatic ductal adenocarcinoma (PDAC) is characterized by extensive desmoplasia with fibroblasts as
Publikováno v:
Medicine. 101:e30692
The World Health Organization states prevention of chronic diseases should be based on good lifestyle behaviors and healthy diets as they can reduce the risk of chronic diseases by 80%. The theory of traditional Chinese medicine constitution (TCMC) e
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
5-methoxytryptophan (5-MTP) is a newly discovered tryptophan metabolite which controls stress-induced inflammatory signals. To determine whether 5-MTP protects against stress-induced mesenchymal stem cell (MSC) senescence, we incubated bone marrow-de