Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Min-Chul Kwon"'
Autor:
Sung-Soo Kim, HyeonSeok Shin, Kyung-Geun Ahn, Young-Min Park, Min-Chul Kwon, Jae-Min Lim, Eun-Kyung Oh, Yumi Kim, Seung-Man Han, Dong-Young Noh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Mass spectrometry (MS) based proteomics is widely used for biomarker discovery. However, often, most biomarker candidates from discovery are discarded during the validation processes. Such discrepancies between biomarker discovery and valida
Externí odkaz:
https://doaj.org/article/324188ddd1634f11a207e0d265af33f2
Autor:
Ekaterina A. Semenova, Min-chul Kwon, Kim Monkhorst, Ji-Ying Song, Rajith Bhaskaran, Oscar Krijgsman, Thomas Kuilman, Dennis Peters, Wieneke A. Buikhuisen, Egbert F. Smit, Colin Pritchard, Miranda Cozijnsen, Jan van der Vliet, John Zevenhoven, Jan-Paul Lambooij, Natalie Proost, Erwin van Montfort, Arno Velds, Ivo J. Huijbers, Anton Berns
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 631-643 (2016)
Small cell lung cancer (SCLC) is an aggressive neuroendocrine tumor, and no effective treatment is available to date. Mouse models of SCLC based on the inactivation of Rb1 and Trp53 show frequent amplifications of the Nfib and Mycl genes. Here, we re
Externí odkaz:
https://doaj.org/article/0c5e4b5dae114c238369da8b5e06aff1
Autor:
Ivo J Huijbers, Rahmen Bin Ali, Colin Pritchard, Miranda Cozijnsen, Min‐Chul Kwon, Natalie Proost, Ji‐Ying Song, Hilda de Vries, Jitendra Badhai, Kate Sutherland, Paul Krimpenfort, Ewa M Michalak, Jos Jonkers, Anton Berns
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 2, Pp 212-225 (2014)
Abstract Human cancers modeled in Genetically Engineered Mouse Models (GEMMs) can provide important mechanistic insights into the molecular basis of tumor development and enable testing of new intervention strategies. The inherent complexity of these
Externí odkaz:
https://doaj.org/article/eb23552beda443f999513453e1461b4a
Autor:
Shanna M. Hogeling, Duy Minh Lê, Nikita La Rose, Min Chul Kwon, Albertus T.J. Wierenga, Fiona A.J. van den Heuvel, Vincent van den Boom, Anna Kuchnio, Ulrike Philippar, Gerwin Huls, Jan Jacob Schuringa
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Acute myeloid leukemia (AML) remains challenging to treat, which in part relates to genetic heterogeneity of the disease, to the protective tumor microenvironment driving resistance to therapy, and also to immune evasion characteristics of leukemic c
Externí odkaz:
https://doaj.org/article/b12e34c2d21c432d86cb3d9b8a8be138
Autor:
Yoon-Young Kim, Jin-Sook Moon, Min-chul Kwon, Juhee Shin, Sun-Kyoung Im, Hyun-A Kim, Jin-Kwan Han, Young-Yun Kong
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88811 (2014)
During gastrulation, distinct lineage specification into three germ layers, the mesoderm, endoderm and ectoderm, occurs through an elaborate harmony between signaling molecules along the embryonic proximo-distal and anterior-posterior axes, and Nodal
Externí odkaz:
https://doaj.org/article/98efbf71c534402396021257985cfe2a
Autor:
Juhee Shin, Seok Hong Lee, Min-Chul Kwon, Dong Kwon Yang, Ha-Rim Seo, Jaetaek Kim, Yoon-Young Kim, Sun-Kyoung Im, Evan Dale Abel, Kyong-Tai Kim, Woo Jin Park, Young-Yun Kong
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53577 (2013)
Mitochondria are key organelles dedicated to energy production. Crif1, which interacts with the large subunit of the mitochondrial ribosome, is indispensable for the mitochondrial translation and membrane insertion of respiratory subunits. To explore
Externí odkaz:
https://doaj.org/article/4c8cbf04b21246659ad8b30804500836
Autor:
Balpreet Bhogal, Barbara A. Weir, Ramona Crescenzo, Ann Marien, Min Chul Kwon, Ulrike Philippar, Glenn S. Cowley
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The methyltransferase domain of DNA methyltransferase protein 1 is an essential functional domain in acute myeloid leukemia, which is independent of DNMT3A mutation.
Externí odkaz:
https://doaj.org/article/4cb0bcf1331e411599809aa13de6b330
Publikováno v:
Acta Entomologica Musei Nationalis Pragae. :197-210
The trictenotomid genus Autocrates Thomson, 1860 is remarkable for its large and robust adults, but its larval morphology and bionomics have been unknown over the last 160 years. Here, we describe and illustrate in detail the eggs, and also the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8467a30d07102a5e00a50ef98764214a
https://doi.org/10.37520/aemnp.2022.015
https://doi.org/10.37520/aemnp.2022.015
Autor:
Min Chul Kwon, Olivier Querolle, Xuedong Dai, Jan Willem Thuring, Tinne Verhulst, Ann Marien, Dries Goffin, Wei Cai, Vikki Keersmaekers, Filmon Eyassu, Karin Verstraeten, Sara El Ashkar, Shanna M Hogeling, Frank Jacob, Petra Vinken, Nicolas Darville, Vineet Pande, Daniel Krosky, Gregor Urbanietz, Bie Verbist, Lucille A. Ferrante, Christina Diane Drenberg, David Wilson, Ricardo M. Attar, Jan Jacob Schuringa, Nikki Daskalakis, Kathryn Packman, Christine Pietsch, Yusri Elsayed, Ulrike Philippar
Publikováno v:
Blood. 140:5928-5929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc637fd2b48b32c40a713ec792434dbb
https://doi.org/10.1182/blood-2022-168921
https://doi.org/10.1182/blood-2022-168921
Autor:
Balpreet Bhogal, Barbara A. Weir, Ramona Crescenzo, Ann Marien, Min Chul Kwon, Ulrike Philippar, Glenn S. Cowley
Publikováno v:
Communications biology. 5(1)
Aberrant DNA methylation patterns are a prominent feature of cancer. Methylation of DNA is mediated by the DNA methyltransferase (DNMT) protein family, which regulates de novo (DNMT3A and DNMT3B) and maintenance (DNMT1) methylation. Mutations in DNMT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75688cd0955d1f690bbb87f7d68fdebc
https://pubmed.ncbi.nlm.nih.gov/36329185
https://pubmed.ncbi.nlm.nih.gov/36329185