Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Min-Chih Cheng"'
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Schizophrenia is a chronic, devastating mental disorder with complex genetic components. Given the advancements in the molecular genetic research of schizophrenia in recent years, there is still a lack of genetic tests that can be used in clinical se
Externí odkaz:
https://doaj.org/article/9e0b2af103964e239b4b408abcd2410b
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
ObjectiveSchizophrenia is a chronic debilitating neurobiological disorder of aberrant synaptic connectivity and synaptogenesis. Postsynaptic density (PSD)–related proteins in N-methyl-D-aspartate receptor–postsynaptic signaling complexes are cruc
Externí odkaz:
https://doaj.org/article/0bfb7ddbc75f43d99cdec9b3867e3a32
Autor:
Chia-Hsiang Chen, Min-Chih Cheng, Ailing Huang, Tsung-Ming Hu, Lieh-Yung Ping, Yu-Syuan Chang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Deleterious mutations of MECP2 are responsible for Rett syndrome, a severe X-linked childhood neurodevelopmental disorder predominates in females, male patients are considered fatal. However, increasing reports indicate that some MECP2 mutations may
Externí odkaz:
https://doaj.org/article/730d3c5d05914b9b8ee61a3d99043b8c
Autor:
Tsung-Ming Hu, Hsiang-Sheng Chung, Lieh-Yung Ping, Shih-Hsin Hsu, Hsin-Yao Tsai, Shaw-Ji Chen, Min-Chih Cheng
Publikováno v:
Brain Sciences, Vol 10, Iss 8, p 545 (2020)
Valproic acid (VPA) is a multifunctional medication used for the treatment of epilepsy, mania associated with bipolar disorder, and migraine. The pharmacological effects of VPA involve a variety of neurotransmitter and cell signaling systems, but the
Externí odkaz:
https://doaj.org/article/97eae980d52948ee945ccc73959121ca
Autor:
Jun-Ming Li, Chao-Lin Lu, Min-Chih Cheng, Sy-Ueng Luu, Shih-Hsin Hsu, Tsung-Ming Hu, Hsin-Yao Tsai, Chia-Hsiang Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85373 (2014)
Aberrant synaptic dysfunction is implicated in the pathogenesis of schizophrenia. The DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 (SAPAP2) located at the post-synaptic density of neuronal cells is involved in the neuronal synaptic func
Externí odkaz:
https://doaj.org/article/2bec6857ddc84dc684adf701675b0846
Autor:
Min-Chih Cheng, Chao-Lin Lu, Sy-Ueng Luu, Ho-Min Tsai, Shih-Hsin Hsu, Tzu-Ting Chen, Chia-Hsiang Chen
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15107 (2010)
Hypofunction of N-methyl-D-aspartate (NMDA) receptor-mediated signal transduction has been implicated in the pathophysiology of schizophrenia. Post-synaptic density protein 95 (PSD95) plays a critical role in regulating the trafficking and activity o
Externí odkaz:
https://doaj.org/article/3ece60630b394a5bac0f92eb316f1499
Autor:
Min-Chih Cheng, Chao-Lin Lu, Sy-Ueng Luu, Ho-Min Tsai, Shih-Hsin Hsu, Tzu-Ting Chen, Chia-Hsiang Chen
Publikováno v:
PLoS ONE, Vol 5, Iss 12 (2010)
Externí odkaz:
https://doaj.org/article/ab5689248fef4cb5a2ffbaaf4f504636
Autor:
Min-Chih Cheng, 鄭敏志
98
Schizophrenia is a common psychiatric disorder with a prevalence of approximately 1 % of the general population worldwide (0.3~1 % in Taiwan) and is characterized by psychotic symptoms such as hallucinations, delusions and bizarre behaviors.
Schizophrenia is a common psychiatric disorder with a prevalence of approximately 1 % of the general population worldwide (0.3~1 % in Taiwan) and is characterized by psychotic symptoms such as hallucinations, delusions and bizarre behaviors.
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/75133634106353627105
Publikováno v:
Psychiatric genetics. 33(1)
The alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors significantly regulate the synaptic transmission and functions of various synaptic receptors. This study aimed to identify single nucleotide mutations in the glutamate recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5b047fc3efc5932bec244e4371121c
https://pubmed.ncbi.nlm.nih.gov/36617743
https://pubmed.ncbi.nlm.nih.gov/36617743
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 5; Pages: 783
Schizophrenia is a complex mental disorder with a genetic component. The GRIK gene family encodes ionotropic glutamate receptors of the kainate subtype, which are considered candidate genes for schizophrenia. We screened for rare and pathogenic mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c728c5a8d9df431bf016ad9ae7284b