Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Min Whan Jung"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Animals often display choice bias, or a preference for one option over the others, which can significantly impede learning new tasks. Delayed match-to-sample (DMS) tasks with two-alternative choices of lickports on the left and right have be
Externí odkaz:
https://doaj.org/article/2580d9284da045a5bd98a571b18e3026
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113228- (2023)
Summary: Social and reward signal processing and their association are critical elements of social motivation. Despite the use of reward learning to improve the social interactions of patients with autism spectrum disorder (ASD), the underlying neura
Externí odkaz:
https://doaj.org/article/2a89c9f174d74d6282412b67db372a59
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102439- (2023)
Summary: In contrast to other techniques utilized in physiological studies, calcium imaging can visualize target neurons located deep in the brain. Here, we present a protocol for one-photon calcium imaging of dorsal and ventral CA1 neurons in head-f
Externí odkaz:
https://doaj.org/article/81112fb025074016a342be584e935497
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-18 (2022)
Abstract Background A core symptom of autism spectrum disorder (ASD) is repetitive and restrictive patterns of behavior. Cognitive inflexibility has been proposed as a potential basis for these symptoms of ASD. More generally, behavioral inflexibilit
Externí odkaz:
https://doaj.org/article/2305b77dbd0046b3ad0e77dd2b8327d7
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112094- (2023)
Summary: A large body of evidence indicates functional variations along the hippocampal longitudinal axis. To investigate whether and how value and outcome processing vary between the dorsal (DH) and the ventral hippocampus (VH), we examined neuronal
Externí odkaz:
https://doaj.org/article/29cfafac368b432a97f63a99e2593f42
Autor:
Woohyun Kim, Jae Jin Shin, Yu Jin Jeong, Kyungdeok Kim, Jung Won Bae, Young Woo Noh, Seungjoon Lee, Woochul Choi, Se-Bum Paik, Min Whan Jung, Eunee Lee, Eunjoon Kim
Publikováno v:
eLife, Vol 11 (2022)
Social deficit is a major feature of neuropsychiatric disorders, including autism spectrum disorders, schizophrenia, and attention-deficit/hyperactivity disorder, but its neural mechanisms remain unclear. Here, we examined neuronal discharge characte
Externí odkaz:
https://doaj.org/article/d8f5356a8bfc458cb2ef94ae9e3b671f
Autor:
Eunee Lee, Seungjoon Lee, Jae Jin Shin, Woochul Choi, Changuk Chung, Suho Lee, Jihye Kim, Seungmin Ha, Ryunhee Kim, Taesun Yoo, Ye-Eun Yoo, Jisoo Kim, Young Woo Noh, Issac Rhim, Soo Yeon Lee, Woohyun Kim, Taekyung Lee, Hyogeun Shin, Il-Joo Cho, Karl Deisseroth, Sang Jeong Kim, Joo Min Park, Min Whan Jung, Se-Bum Paik, Eunjoon Kim
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
How NMDAR and GABA neuronal dysfunctions result in impaired social behaviour is unclear. Here, the authors show that NMDARs and gap junctions in cortical PV interneurons modulate burst firing, affecting social behaviour.
Externí odkaz:
https://doaj.org/article/be579d8154684279867ebaa15847607e
Autor:
Jung Won Bae, Huijeong Jeong, Young Ju Yoon, Chan Mee Bae, Hyeonsu Lee, Se-Bum Paik, Min Whan Jung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Intratelencephalic and pyramidal tract neurons are two major types of cortical excitatory neurons that project to cortical and subcortical structures. The authors show that in the prefrontal cortex the two populations have different roles for the mai
Externí odkaz:
https://doaj.org/article/0c1518962f8345dabc4fd60c3712ecac
Autor:
Eun Ju Shin, Yunsil Jang, Soyoun Kim, Hoseok Kim, Xinying Cai, Hyunjung Lee, Jung Hoon Sul, Sung-Hyun Lee, Yeonseung Chung, Daeyeol Lee, Min Whan Jung
Publikováno v:
eLife, Vol 10 (2021)
Studies in rats, monkeys, and humans have found action-value signals in multiple regions of the brain. These findings suggest that action-value signals encoded in these brain structures bias choices toward higher expected rewards. However, previous e
Externí odkaz:
https://doaj.org/article/bb76fb9af55b4812a9b6b056f6538121
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract It is generally believed that the hippocampus plays a crucial role in declarative memory—remembering facts and events—but not in gradual stimulus-response association or incremental value learning. Based on the finding that CA1 conveys s
Externí odkaz:
https://doaj.org/article/57412bb9e8ef4a70a7dbe27b0a763eeb