Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Min Wen Ku"'
Autor:
Min Wen Ku, Pierre Authié, Fabien Nevo, Philippe Souque, Maryline Bourgine, Marta Romano, Pierre Charneau, Laleh Majlessi
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Ku et al. report a lentiviral (LV) vector system in which expression of vaccine antigens is driven by β2-microglobulin (β2m) promoter. Conducting comparative studies in mice and rats, they find that LV-based vaccine outperforms the ‘gold-standard
Externí odkaz:
https://doaj.org/article/fe683d23065d4838988c80289e525fa0
Autor:
Benjamin Vesin, Pierre Authié, Catherine Blanc, Ingrid Fert, Amandine Noirat, Fabien Le Chevalier, Yu Wei, Min-Wen Ku, Kirill Nemirov, François Anna, David Hardy, Cyril Planchais, Hugo Mouquet, Françoise Guinet, Pierre Charneau, Laleh Majlessi, Maryline Bourgine
Publikováno v:
Vaccines, Vol 11, Iss 1, p 12 (2022)
Following the breakthrough of numerous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants in recent months and the incomplete efficiency of the currently available vaccines, development of more effective vaccines is desirable. Non-
Externí odkaz:
https://doaj.org/article/34cede2634f945f8b23c021e868dce71
Autor:
Jodie Lopez, François Anna, Pierre Authié, Alexandre Pawlik, Min-Wen Ku, Catherine Blanc, Philippe Souque, Fanny Moncoq, Amandine Noirat, David Hardy, Wladimir Sougakoff, Roland Brosch, Françoise Guinet, Pierre Charneau, Laleh Majlessi
Publikováno v:
Cell Reports
Cell Reports, 2022, 40 (4), pp.111142. ⟨10.1016/j.celrep.2022.111142⟩
Cell Reports, 2022, 40 (4), pp.111142. ⟨10.1016/j.celrep.2022.111142⟩
International audience; Lentiviral vectors (LVs) are highly efficient at inducing CD8+ T cell responses. However, LV-encoded antigens are processed inside the cytosol of antigen-presenting cells, which does not directly communicate with the endosomal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19035379ada3bffdacfa39659f1481f2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03909608/file/1-s2.0-S2211124722009512-main.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03909608/file/1-s2.0-S2211124722009512-main.pdf
Publikováno v:
Expert Review of Vaccines
Expert Review of Vaccines, 2021, 20 (12), pp.1571-1586. ⟨10.1080/14760584.2021.1988854⟩
Expert Review of Vaccines, 2021, 20 (12), pp.1571-1586. ⟨10.1080/14760584.2021.1988854⟩
International audience; Introduction: Lentiviral vectors have emerged as powerful vectors for vaccination, due to their high efficiency to transduce dendritic cells and to induce long-lasting humoral immunity, CD8 + T cells, and effective protection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc29f0db415054eb05fbcb4e4ebea65b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03695112/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03695112/document
Autor:
Jodie, Lopez, François, Anna, Pierre, Authié, Alexandre, Pawlik, Min-Wen, Ku, Catherine, Blanc, Philippe, Souque, Fanny, Moncoq, Amandine, Noirat, David, Hardy, Wladimir, Sougakoff, Roland, Brosch, Françoise, Guinet, Pierre, Charneau, Laleh, Majlessi
Publikováno v:
Cell reports. 40(4)
Lentiviral vectors (LVs) are highly efficient at inducing CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76bc0f65ef48ee495b1619f00961e96c
https://pubmed.ncbi.nlm.nih.gov/35905717
https://pubmed.ncbi.nlm.nih.gov/35905717
Autor:
Francina Langa Vives, Jodie Lopez, Catherine Blanc, llta Lafosse, Ingrid Fert, Sébastien Chardenoux, Pierre Authié, Philippe Souque, Benjamin Vesin, Laleh Majlessi, Amandine Noirat, Kirill Nemirov, Fabien Nevo, Min-Wen Ku, Françoise Guinet, Fanny Moncoq, François Anna, David Hardy, Maryline Bourgine, Delphine Cussigh, Pierre Charneau
COVID-19 vaccines already in use or in clinical development may have safety concerns, limited immunogenicity in high-risk groups or reduced efficacy against emerging SARS-CoV-2 variants. In addition, although the neurotropism of SARS-CoV-2 is well es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58292b8dcd994f18542068d007e172b3
https://doi.org/10.21203/rs.3.rs-415309/v1
https://doi.org/10.21203/rs.3.rs-415309/v1
Autor:
Pierre Charneau, Min-Wen Ku, Philippe Souque, Fanny Moncoq, Ilta Lafosse, François Anna, Sébastien Chardenoux, David Hardy, Maryline Bourgine, Catherine Blanc, Pierre Authié, Benjamin Vesin, Jodie Lopez, Kirill Nemirov, Fabien Nevo, Françoise Guinet, Amandine Noirat, Francina Langa Vives, Laleh Majlessi
SummaryNon-integrative, non-cytopathic and non-inflammatory lentiviral vectors are particularly suitable for mucosal vaccination and recently emerge as a promising strategy to elicit sterilizing prophylaxis against SARS-CoV-2 in preclinical animal mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88c938b913d8b02f06b2e77ad23aea5f
https://doi.org/10.1101/2021.02.03.429211
https://doi.org/10.1101/2021.02.03.429211
Autor:
Hugo Mouquet, Benjamin Vesin, Houda Tabbal, Françoise Guinet, Jodie Lopez, Pierre Authié, Laurence Fiette, Marine Le Dudal, Catherine Blanc, François Anna, Maryline Bourgine, Nicolas Escriou, David Hardy, Fanny Moncoq, Kirill Nemirov, Fabien Nevo, Annette Martin, Pierre Charneau, Philippe Souque, Laleh Majlessi, Emeline Simon, Amandine Noirat, Min Wen Ku
Publikováno v:
Cell Host & Microbe
Cell Host & Microbe, 2020, ⟨10.1016/j.chom.2020.12.010⟩
Cell Host & Microbe, 2020, ⟨10.1016/j.chom.2020.12.010⟩
To develop a vaccine candidate against COVID-19, we generated a Lentiviral Vector (LV), eliciting neutralizing antibodies against the Spike glycoprotein of SARS-CoV-2. Systemic vaccination by this vector in mice, in which the expression of the SARS-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9678a43eb2bcba09b95517b74144677f
https://hal-pasteur.archives-ouvertes.fr/pasteur-03108682/file/1-s2.0-S1931312820306727-main.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03108682/file/1-s2.0-S1931312820306727-main.pdf
Autor:
Yunhao Zhai, Girija Goyal, Pranav Prabhala, Aditya Patil, Min Sun Kim, Abidemi Junaid, Min Wen Ku, Gautam Mahajan, Bruce Bausk, Tal Gilboa, Roey Lazarovits, Sanjay Sharma, Limor Cohen, Thomas Ferrante, David R Walt, Donald E Ingber
Publikováno v:
The Journal of Immunology. 208:116.01-116.01
New vaccine candidates evaluated in animals can lead to unpredicted toxicities or poor efficacy in human clinical trials due to species-specific differences in immune responses. To address this problem, we developed the human ectopic lymphoid follicl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::273906191f23f4df38e92ff3e805c654
https://doi.org/10.4049/jimmunol.208.supp.116.01
https://doi.org/10.4049/jimmunol.208.supp.116.01
Autor:
Amandine Noirat, Fanny Moncoq, Pierre Charneau, Laleh Majlessi, Jodie Lopez, Philippe Souque, Kirill Nemirov, Fabien Nevo, Pierre Authié, Nicolas Escriou, Maryline Bourgine, Min-Wen Ku, Laurence Fiette, François Anna, Emeline Simon, Hugo Mouquet, Houda Tabbal, Catherine Blanc, Benjamin Vesin, Marine Le Dudal, Françoise Guinet, Annette Martin
We developed a potent vaccination strategy, based on lentiviral vector (LV), capable of inducing neutralizing antibodies specific to the Spike glycoprotein (S) of SARS-CoV-2, the etiologic agent of CoronaVirus Disease 2019 (COVID-19). Among several L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69095e7f3afc59207cfefd5ea05c4759
https://doi.org/10.1101/2020.07.21.214049
https://doi.org/10.1101/2020.07.21.214049