Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Min K, Tsai"'
Autor:
Christopher W. Murray, Jennifer J. Brady, Mingqi Han, Hongchen Cai, Min K. Tsai, Sarah E. Pierce, Ran Cheng, Janos Demeter, David M. Feldser, Peter K. Jackson, David B. Shackelford, Monte M. Winslow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
LKB1 tumour suppressor gene is frequently mutated in lung adenocarcinoma. Here the authors show that in genetically engineered mouse models of lung cancer Lkb1 restoration induces growth arrest and drives neoplastic cells toward a more differentiated
Externí odkaz:
https://doaj.org/article/fac054136b674b659d92c440e9e9e2b2
Autor:
Rui Tang, Emily G. Shuldiner, Marcus Kelly, Christopher W. Murray, Jess D. Hebert, Laura Andrejka, Min K. Tsai, Nicholas W. Hughes, Mitchell I. Parker, Hongchen Cai, Yao-Cheng Li, Geoffrey M. Wahl, Roland L. Dunbrack, Peter K. Jackson, Dmitri A. Petrov, Monte M. Winslow
Publikováno v:
Nature Cell Biology. 25:159-169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d57cd5248d3f14dde94a8638efa11d0
https://doi.org/10.1038/s41556-022-01049-w
https://doi.org/10.1038/s41556-022-01049-w
Autor:
Rui Tang, Christopher W Murray, Ian L Linde, Nicholas J Kramer, Zhonglin Lyu, Min K Tsai, Leo C Chen, Hongchen Cai, Aaron D Gitler, Edgar Engleman, Wonjae Lee, Monte M Winslow
Publikováno v:
eLife, Vol 9 (2020)
Cell-cell interactions influence all aspects of development, homeostasis, and disease. In cancer, interactions between cancer cells and stromal cells play a major role in nearly every step of carcinogenesis. Thus, the ability to record cell-cell inte
Externí odkaz:
https://doaj.org/article/13a418d59ffc4122921111ddb10c3638
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
(Updated, with minor text changes and rearrangements.) Figure S1-S4 (related to Figure 1) provide details on the selected genes and method. Figure S5 (related to Figure 2) shows the percentiles of all sgRNAs. Figure S6-S8 (related to Figure 3) presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb999fe9b53b0a94ffbad60dec52b16e
https://doi.org/10.1158/2159-8290.22540429
https://doi.org/10.1158/2159-8290.22540429
Autor:
Monte M. Winslow, Pauline Chu, Christian A. Kunder, Rosanna K. Ma, Laura Andrejka, Rui Tang, Ian P. Winters, Chuan Li, Min K. Tsai, Jennifer J. Brady, Christopher W. Murray
Summary of gene sets generated from previously published analyses of the LKB1-deficient state in human lung adenocarcinoma cell lines and tumors as well as genetically engineered mouse models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180f5e1c5fca29afb931367a73caadfa
https://doi.org/10.1158/2159-8290.22532464
https://doi.org/10.1158/2159-8290.22532464
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
Cancer genotyping has identified a large number of putative tumor suppressor genes. Carcinogenesis is a multistep process, but the importance and specific roles of many of these genes during tumor initiation, growth, and progression remain unknown. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b404e969247084e511f71eff4ac10a
https://doi.org/10.1158/2159-8290.c.6549376
https://doi.org/10.1158/2159-8290.c.6549376
Autor:
Monte M. Winslow, Charles Swanton, Dmitri A. Petrov, Christopher D. McFarland, Le Cong, Christian A. Kunder, Wen-Yang Lin, Maryam Yousefi, Shi Ya C. Lee, Leo C. Chen, King L. Hung, Rui Tang, Emily L. Ashkin, Emily G. Shuldiner, Nicholas W. Hughes, Christopher W. Murray, Laura Andrejka, Min K. Tsai, Chuan Li, Su Kit Chew, Hongchen Cai
Table S2. The information of sgRNA vectors in the high content Lenti-sgTS102/Cre pool.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd3cce0b27516cffd3dcfa9479b7b40
https://doi.org/10.1158/2159-8290.22540423
https://doi.org/10.1158/2159-8290.22540423
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Supplementary Table from Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042b103656126ba4dbaf5850295d0cba
https://doi.org/10.1158/0008-5472.22430772.v1
https://doi.org/10.1158/0008-5472.22430772.v1
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Lung cancer is the leading cause of cancer death worldwide, with lung adenocarcinoma being the most common subtype. Many oncogenes and tumor suppressor genes are altered in this cancer type, and the discovery of oncogene mutations has led to the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc114c2b785293faf863f3455b7de909
https://doi.org/10.1158/0008-5472.c.6513717.v1
https://doi.org/10.1158/0008-5472.c.6513717.v1
Autor:
Monte M. Winslow, Dmitri A. Petrov, Christian A. Kunder, Charles Swanton, Pauline Chu, Su-Kit Chew, Caterina I. Colón, Pegah Yakhchalian, Chuan Li, Wen-Yang Lin, Min K. Tsai, Minwei Wang, Leo Chen, Laura Andrejka, Saswati Karmakar, Emily L. Ashkin, Hongchen Cai, Jess D. Hebert, Christopher W. Murray, Carly Weiss, Gábor Boross, Maryam Yousefi
Supplementary Data from Combinatorial Inactivation of Tumor Suppressors Efficiently Initiates Lung Adenocarcinoma with Therapeutic Vulnerabilities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7855b95605a95a915f9e9ff3b567f9d6
https://doi.org/10.1158/0008-5472.22430793
https://doi.org/10.1158/0008-5472.22430793