Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Min Jie Alvin Tan"'
Autor:
Charlotte Flory, Kitt Wing Ki Chan, Jade K. Forwood, Julien Lescar, Sai Wang, Min Jie Alvin Tan, Dahai Luo, Subhash G. Vasudevan
Publikováno v:
RNA. 28:177-193
The commitment to replicate the RNA genome of flaviviruses without a primer involves RNA-protein interactions that have been shown to include the recognition of the stem-loop A (SLA) in the 5' untranslated region (UTR) by the nonstructural protein NS
Autor:
Sai Wang, Marie Jennifer Reolo, Ann-Marie Chacko, Min Jie Alvin Tan, Satoru Watanabe, Milly M. Choy, Carla Bianca Luena Victorio, Menchie Manuel, Subhash G. Vasudevan, Kitti Wing Ki Chan, Colin X Cheng, Joanne Ong
Publikováno v:
ACS Infectious Diseases. 7:3277-3291
Dengue virus (DENV) non-structural protein 5 (NS5) is critical for viral RNA synthesis within endoplasmic reticulum (ER)-derived replication complexes in the cytoplasm; however a proportion of NS5 is known to be localized to the nucleus of infected c
Autor:
Sean Yao Zu Kong, Subhash G. Vasudevan, Kitti Wing Ki Chan, Jocelyn Y Jin, Min Jie Alvin Tan, Nancy G Brown
Publikováno v:
Journal of General Virology. 101:941-953
The dengue virus (DENV) replication complex is made up of its non-structural (NS) proteins and yet-to-be identified host proteins, but the molecular interactions between these proteins are not fully elucidated. In this work, we sought to uncover the
Autor:
Amanda Makha, Bifani, Kitti Wing Ki, Chan, Doortje, Borrenberghs, Min Jie Alvin, Tan, Wint Wint, Phoo, Satoru, Watanabe, Olivia, Goethals, Subhash G, Vasudevan, Milly M, Choy
Publikováno v:
Antiviral Research. 210:105517
Flaviviruses are vector-borne pathogens capable of causing devastating human diseases. The re-emergence of Zika in 2016 notoriously led to a widescale epidemic in the Americas. New daunting evidence suggests that a single mutation in Zika virus genom
Publikováno v:
The Biochemist. 39:18-21
Many flaviviruses cause important and serious human diseases, including yellow fever, West Nile, Japanese encephalitis and tick-borne encephalitis viruses. Two further flaviviruses, the closely related dengue and Zika virus, have emerged as significa
Autor:
Subhash G. Vasudevan, Ivan Ng, Satoru Watanabe, Jade K. Forwood, Crystall M.D. Swarbrick, Kate Smith, Wuan Geok Saw, Min Jie Alvin Tan, David A. Jans, Chin Piaw Gwee, Sarah J. Jeffress, Kitti Wing Ki Chan, Gerhard Grüber
Publikováno v:
ACS infectious diseases. 5(6)
The Zika virus (ZIKV) epidemic in the Americas was alarming because of its link with microcephaly in neonates and Guillain-Barre syndrome in adults. The unusual pathologies induced by ZIKV infection and the knowledge that the flaviviral nonstructural
The papillomavirus E2 protein executes numerous essential functions related to viral transcription, replication of viral DNA, and viral genome maintenance. Because E2 lacks enzymatic activity, many of these functions are mediated by interactions with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::563a9c8f8b5edcafd363005be538b3e8
https://europepmc.org/articles/PMC6052296/
https://europepmc.org/articles/PMC6052296/
Autor:
Satoru Watanabe, Subhash G. Vasudevan, Min Jie Alvin Tan, Kitti Wing Ki Chan, Chin Piaw Gwee, Ivan Ng, Sean Yao Zu Kong
Publikováno v:
Cells
The Zika virus (ZIKV) non-structural protein 5 (NS5) plays multiple viral and cellular roles during infection, with its primary role in virus RNA replication taking place in the cytoplasm. However, immunofluorescence assay studies have detected the p
Autor:
Min Jie Alvin Tan, J. W. Harper, Elizabeth A. White, Rebecca Kramer, Peter M. Howley, Sebastian D. Hayes
Publikováno v:
Journal of Virology. 86:13174-13186
We have begun to define the human papillomavirus (HPV)-associated proteome for a subset of the more than 120 HPV types that have been identified to date. Our approach uses a mass spectrometry-based platform for the systematic identification of intera
Publikováno v:
Virology.
Cell infection by parvoviruses requires that capsids be delivered from outside the cell to the cytoplasm, followed by genome trafficking to the nucleus. Here we microinject capsids into cells that lack receptors and followed their movements within th