Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Min Hwa Shin"'
Autor:
Jeongsoo Kim, Tae-Jin Kim, Sehyun Chae, Hyojeong Ha, Yejin Park, Sunghee Park, Chul Joo Yoon, Seon Ah Lim, Hyemin Lee, Jiyoung Kim, Jungwon Kim, Kyungtaek Im, Kyunghye Lee, Jeongmin Kim, Daham Kim, Eunju Lee, Min Hwa Shin, Serk In Park, Inmoo Rhee, Keehoon Jung, Jeewon Lee, Keun Hwa Lee, Daehee Hwang, Kyung-Mi Lee
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background In the myeloid compartment of the tumor microenvironment, CD244 signaling has been implicated in immunosuppressive phenotype of monocytes. However, the precise molecular mechanism and contribution of CD244 to tumor immunity in mon
Externí odkaz:
https://doaj.org/article/b9d69d09111a49bdb32d80e3ebb65c32
Autor:
Hyungsin Kim, Jeongsoo Kim, Jason K. Sa, Byung-Kyu Ryu, Kyung-Jae Park, Jiyoung Kim, Hyojeong Ha, Yejin Park, Min Hwa Shin, Jungwon Kim, Hyemin Lee, Daham Kim, Kyunghye Lee, Byunghyun Jang, Kyung-Mi Lee, Shin-Hyuk Kang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113553- (2022)
To overcome the hurdles of immunotherapy, we investigated whether calcipotriol, a synthetic vitamin D analog, could overcome the immune evasion of glioblastoma multiforme (GBM) by modulating immune responses and the immunosuppressive tumor microenvir
Externí odkaz:
https://doaj.org/article/0cdba935b7a04b71916e616b274e78f1
Publikováno v:
Cells, Vol 12, Iss 12, p 1606 (2023)
Adoptive cell therapy using chimeric antigen receptor (CAR) technology is one of the most advanced engineering platforms for cancer immunotherapy. CAR-T cells have shown remarkable efficacy in the treatment of hematological malignancies. However, the
Externí odkaz:
https://doaj.org/article/c3cacb824d144db393e868aa123e6566
Autor:
Tae-Jin Kim, Gayoung Park, Jeongmin Kim, Seon Ah Lim, Jiyoung Kim, Kyungtaek Im, Min Hwa Shin, Yang-Xin Fu, Maria-Luisa Del Rio, Jose-Ignacio Rodriguez-Barbosa, Cassian Yee, Kyung-Suk Suh, Seong-Jin Kim, Sang-Jun Ha, Kyung-Mi Lee
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
BTLA is established as a negative regulator of natural killer T (NKT) cell function, and share its ligand HVEM with CD160. Here the authors show, by analyzing NKT activation in CD160-deficient mice or with BTLA blockade, that CD160 synergizes with BT
Externí odkaz:
https://doaj.org/article/c01494c358d541df8aa8b760a2cb9a37
Autor:
Yunlong He, Wentao Zhu, Min Hwa Shin, Joy Gary, Chengyu Liu, Wendy Dubois, Shelley B. Hoover, Shunlin Jiang, Eryney Marrogi, Beverly Mock, R. Mark Simpson, Jing Huang
Publikováno v:
Stem Cell Reports, Vol 8, Iss 6, Pp 1630-1644 (2017)
Bone marrow-derived mesenchymal stem cells (BMSCs) are proposed as the cells of origin of several subtypes of osteosarcoma (OS). However, signals that direct BMSCs to form different subtypes of OS are unclear. Here we show that the default tumor type
Externí odkaz:
https://doaj.org/article/cf90561569b445598bdb324e83a3f4a3
Autor:
Seon Ah Lim, Jungwon Kim, Seunghyun Jeon, Min Hwa Shin, Joonha Kwon, Tae-Jin Kim, Kyungtaek Im, Youngmin Han, Wooil Kwon, Sun-Whe Kim, Cassian Yee, Seong-Jin Kim, Jin-Young Jang, Kyung-Mi Lee
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Tumor-infiltrating lymphocytes (TILs), found in patients with advanced pancreatic ductal adenocarcinoma (PDAC), are shown to correlate with overall survival (OS) rate. Although majority of TILs consist of CD8+/CD4+ T cells, the presence of NK cells a
Externí odkaz:
https://doaj.org/article/d5ec4496e3ca4cea83cc24b9d81ed0ec
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2531 (2020)
The recent development of high-throughput genomics has revolutionized personalized medicine by identifying key pathways and molecular targets controlling tumor progression and survival. Mitogen-activated protein kinase (MAPK) pathways are examples of
Externí odkaz:
https://doaj.org/article/e30dbd7e3db64f9397887a0630a7d3fd
Autor:
Min Hwa Shin, Yunlong He, Eryney Marrogi, Sajida Piperdi, Ling Ren, Chand Khanna, Richard Gorlick, Chengyu Liu, Jing Huang
Publikováno v:
PLoS Genetics, Vol 12, Iss 2, p e1005884 (2016)
The inactivation of p53 creates a major challenge for inducing apoptosis in cancer cells. An attractive strategy is to identify and subsequently target the survival signals in p53 defective cancer cells. Here we uncover a RUNX2-mediated survival sign
Externí odkaz:
https://doaj.org/article/698dcb8acadd41409071a02ce02d5d13
Publikováno v:
Journal of Tourism and Leisure Research. 34:129-144
Autor:
Min-Hwa Shin
Publikováno v:
Korea Industrial Technology Convergence Society. 27:49-54