Characterizing clinical isolates of Acanthamoeba castellanii with high resistance to polyhexamethylene biguanide in Taiwan

Autor: Fu-Chin Huang, Min-Hsiu Shih, Kai-Fei Chang, Jian-Ming Huang, Jyh-Wei Shin, Wei-Chen Lin

Publikováno v: Journal of Microbiology, Immunology and Infection, Vol 50, Iss 5, Pp 570-577 (2017)

Background/Purpose: Acanthamoeba keratitis (AK), a painful infectious corneal disease, is caused by the free-living pathogenic species Acanthamoeba. The symptoms include corneal infiltrate, epithelial, and stromal destruction, and loss of vision. Cur

Externí odkaz: https://doaj.org/article/24b0c32a6e834a7aba859482aecd16f4

Retinopathy of prematurity in southern Taiwan: A 10-year tertiary medical center study

Autor: Mei-Lun Li, Sheng-Min Hsu, Yi-Sheng Chang, Min-Hsiu Shih, Yung-Chieh Lin, Chyi-Her Lin, Hui-Ju Tsai, Sung-Huei Tseng

Publikováno v: Journal of the Formosan Medical Association, Vol 112, Iss 8, Pp 445-453 (2013)

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness. This retrospective study investigated ROP, including incidence, demographic information,risk factors, treatments, and refractive outcomes, in southern Taiwan over a 10-year p

Externí odkaz: https://doaj.org/article/faf59965eab84effb4d171b088bcc44a

Ocular characteristics in a variant microcephalic primordial dwarfism type II

Autor: Fu Chin Huang, Wan Ju Chen, Min Hsiu Shih

Publikováno v: BMC Pediatrics, Vol 19, Iss 1, Pp 1-4 (2019)
BMC Pediatrics

Background Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) is a rare disease that is assumed to be caused by a pericentrin (PCNT) gene mutation. Clinical manifestations have been reported in pediatrics and neurology; however, onl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff43879b0efa217a38eb17b30f63d64c
http://link.springer.com/article/10.1186/s12887-019-1685-2

Major ocular trauma in Taiwan: 2002–2004 versus 2012–2014

Autor: Chun Chieh Lai, Min Hsiu Shih, Shu Fang Hsiao, Yi Hsun Huang, Yi Sheng Chang, Jia Horung Hung, Wan Ju Chen, Yu Ti Teng, Sheng Min Hsu, Fu Chin Huang, Sung Huei Tseng, Shih Hao Wang, Mei Ling Liu

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports

We investigated the temporal changes in major eye injuries in Taiwan by reviewing the medical records of all patients with ocular trauma hospitalized at the National Cheng Kung University Hospital during 2002–2004 and 2012–2014. A total of 169 ey

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9bd0f010d02f9613b57e279fa6b127
http://link.springer.com/article/10.1038/s41598-018-25030-6

The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage

Autor: Wei Chen Lin, Jyh Wei Shin, Sung-Chou Li, Tao Shen Liu, Min Hsiu Shih, Fu Chin Huang

Publikováno v: International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 6, Iss 3, Pp 251-257 (2016)

Acanthamoeba castellanii is a free-living protozoan pathogen capable of causing a blinding keratitis and fatal granulomatous encephalitis. Current treatment generally involves an hourly application of polyhexamethylene biguanide (PHMB) over a period

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96ddbaaef8781e6ef5fcd476a99b33e3