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Akademický článek

An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines

Autor: Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Haab Brian, Yehia Mechref

Publikováno v: Cells, Vol 13, Iss 19, p 1640 (2024)

Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–

Externí odkaz: https://doaj.org/article/dcbfcea98922479394a4e1d678775c76

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Akademický článek

Targeting Molecular Signaling Pathways and Cytokine Responses to Modulate c-MYC in Acute Myeloid Leukemia

Autor: Kyle Gu, Harry A. May, Min H. Kang

Publikováno v: Frontiers in Bioscience-Scholar, Vol 16, Iss 3, p 15 (2024)

Overexpression of the MYC oncogene, encoding c-MYC protein, contributes to the pathogenesis and drug resistance of acute myeloid leukemia (AML) and many other hematopoietic malignancies. Although standard chemotherapy has predominated in AML therapy

Externí odkaz: https://doaj.org/article/affe596478a1428c9dccfe35529356f5

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Akademický článek

PPE decontamination to overcome PPE shortage in rural area during pandemic

Autor: Abdurrahman Kharbat, Habib Abla, Mahmud Alkul, Ranger Kile, Justin White, Cynthia Reinoso Webb, Steven M. Presley, Min H. Kang

Publikováno v: Infection Prevention in Practice, Vol 3, Iss 3, Pp 100145- (2021)

Summary: Despite remarkable developments in healthcare, the world was not ready to stop the spread of the novel COVID-19 pandemic almost a century after the great influenza pandemic. The explosive increase in the number of patients stalled the health

Externí odkaz: https://doaj.org/article/5f6d858db6564585b21d693552fe1605

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Akademický článek

Antineoplastic Agents Targeting Sphingolipid Pathways

Autor: Alexander Kroll, Hwang Eui Cho, Min H. Kang

Publikováno v: Frontiers in Oncology, Vol 10 (2020)

Emerging studies in the enigmatic area of bioactive lipids have made many exciting new discoveries in recent years. Once thought to play a strictly structural role in cellular function, it has since been determined that sphingolipids and their metabo

Externí odkaz: https://doaj.org/article/82db789405704cbb832598b9c0f29332

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Akademický článek

DNA-PK as an Emerging Therapeutic Target in Cancer

Autor: Ismail S. Mohiuddin, Min H. Kang

Publikováno v: Frontiers in Oncology, Vol 9 (2019)

The DNA-dependent protein kinase (DNA-PK) plays an instrumental role in the overall survival and proliferation of cells. As a member of the phosphatidylinositol 3-kinase-related kinase (PIKK) family, DNA-PK is best known as a mediator of the cellular

Externí odkaz: https://doaj.org/article/28741ed63ac746ffb3891cbb5d3dcff6

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Akademický článek

Effects of Keratinocyte-Derived Cytokine (CXCL-1) on the Development of Theiler's Virus-Induced Demyelinating Disease

Autor: Min H. Kang, Young H. Jin, Byung S. Kim

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)

CXCL-1, also called keratinocyte-derived cytokine (KC), is a predominant chemokine produced in glial cells upon infection with Theiler's murine encephalomyelitis virus (TMEV). In this study, we assessed the role of KC in the development of TMEV-induc

Externí odkaz: https://doaj.org/article/c04d04c92e8045948a59d0a50b4d39f7

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