Zobrazeno 1 - 10
of 246
pro vyhledávání: '"Min H Kang"'
Autor:
Maggie H Chasse, Benjamin K Johnson, Elissa A Boguslawski, Katie M Sorensen, Jessica E Rosien, Min H Kang, C Patrick Reynolds, Lyong Heo, Zachary B Madaj, Ian Beddows, Gabrielle E Foxa, Susan M Kitchen‐Goosen, Bart O Williams, Timothy J Triche Jr, Patrick J Grohar
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 2, Pp n/a-n/a (2021)
Abstract Rhabdoid tumor (RT) is a pediatric cancer characterized by the inactivation of SMARCB1, a subunit of the SWI/SNF chromatin remodeling complex. Although this deletion is the known oncogenic driver, there are limited effective therapeutic opti
Externí odkaz:
https://doaj.org/article/18bf94a3ea2d4e32b5861a62e60c62a8
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74768 (2013)
We previously reported that fenretinide (4-HPR) was cytotoxic to acute lymphoblastic leukemia (ALL) cell lines in vitro in association with increased levels of de novo synthesized dihydroceramides, the immediate precursors of ceramides. However, the
Externí odkaz:
https://doaj.org/article/1b734afa29df41b59132ac856ba3e754
Autor:
Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Haab Brian, Yehia Mechref
Publikováno v:
Cells, Vol 13, Iss 19, p 1640 (2024)
Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–
Externí odkaz:
https://doaj.org/article/dcbfcea98922479394a4e1d678775c76
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 16, Iss 3, p 15 (2024)
Overexpression of the MYC oncogene, encoding c-MYC protein, contributes to the pathogenesis and drug resistance of acute myeloid leukemia (AML) and many other hematopoietic malignancies. Although standard chemotherapy has predominated in AML therapy
Externí odkaz:
https://doaj.org/article/affe596478a1428c9dccfe35529356f5
Autor:
Barbara Szymanska, Urszula Wilczynska-Kalak, Min H Kang, Natalia L M Liem, Hernan Carol, Ingrid Boehm, Daniel Groepper, C Patrick Reynolds, Clinton F Stewart, Richard B Lock
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33894 (2012)
Current regimens for induction therapy of pediatric acute lymphoblastic leukemia (ALL), or for re-induction post relapse, use a combination of vincristine (VCR), a glucocorticoid, and L-asparaginase (ASP) with or without an anthracycline. With cure r
Externí odkaz:
https://doaj.org/article/88670b55056c4fe1b0a9b4f77ad7b243
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42291 (2012)
Inhibition of integrins αvβ3/αvβ5 by the cyclic function-blocking peptide, RGDfV (Arg-Gly-Asp-Phe-Val) can induce apoptosis in both normal cells and tumor cells. We show that RGDfV induced apoptosis in ECV-304 carcinoma cells, increased activity
Externí odkaz:
https://doaj.org/article/11f78323125d44ddac8e0b0dc4b3e9e3
Autor:
Cho, Hwang Eui, Min, H. Kang
Publikováno v:
In Journal of Pharmaceutical and Biomedical Analysis 5 January 2017 132:117-124
Autor:
Alexis C. Boulter, Barry J. Maurer, Meredith Pogue, Min H. Kang, Hwangeui Cho, Amanda Knight, C. Patrick Reynolds, Donald Quick, Sanjay Awasthi, David E. Gerber
Publikováno v:
Cancer Chemotherapy and Pharmacology.
Publikováno v:
Journal of Cellular Physiology. 237:3012-3029
This study provides comprehensive mechanistic evidence for the role of clusterin, a stress-response secretory chaperone protein, in the modulation of intraocular pressure (IOP) by regulating the trabecular meshwork (TM) actin cytoskeleton and the ext
Autor:
Sung-Jen Wei, In-Hyoung Yang, Ismail S. Mohiuddin, Ganesh J. Kshirsagar, Thinh H. Nguyen, Scott Trasti, Barry J. Maurer, Min H. Kang
Publikováno v:
Biochim Biophys Acta Gene Regul Mech
Small cell lung cancer (SCLC) is a neuroendocrine tumor noted for the rapid development of both metastases and resistance to chemotherapy. High mutation burden, ubiquitous loss of TP53 and RB1, and a mutually exclusive amplification of MYC gene famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de1aecac5fe0ab162de54422e302b35
https://europepmc.org/articles/PMC10243594/
https://europepmc.org/articles/PMC10243594/