Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Min‑Koo Choi"'
Publikováno v:
Journal of Animal Science and Technology, Vol 66, Iss 1, Pp 103-114 (2024)
This study was done to investigate the effects of the incorporation of Achyranthes japonica extracts (AJE) in diet on the production parameters of growing pigs. Exp 1: Total, 105 crossbred pigs (average body weight: 24.47 ± 2.46 kg) were used in a 6
Externí odkaz:
https://doaj.org/article/19cea10977fb4283b2b9c2b1d05b1852
Autor:
Ji-Hyeon Jeon, So-Yeon Jeon, Yeon-Ju Baek, Chan-E Park, Min-Koo Choi, Young Taek Han, Im-Sook Song
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 934 (2024)
The quinoline alkaloid 2-(quinoline-8-carboxamido)benzoic acid (2-QBA), which is isolated from Aspergillus sp. SCSIO06786, a deep sea-derived fungus, has been suggested as a therapeutic candidate for the treatment of Parkinson’s disease. We develop
Externí odkaz:
https://doaj.org/article/6a34bbe9da6948b8bdbc83f8a76f1479
Autor:
Min Seo Lee, Jihoon Lee, Minyoung Pang, John Kim, Hyunju Cha, Banyoon Cheon, Min-Koo Choi, Im-Sook Song, Hye Suk Lee
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 799 (2024)
Zastaprazan (JP-1366), a novel potassium-competitive acid blocker, is a new drug for the treatment of erosive esophagitis. JP-1366 is highly metabolized in human, mouse, and dog hepatocytes but moderately metabolized in rat and monkey hepatocytes whe
Externí odkaz:
https://doaj.org/article/d22f1234d718446cb00384ce6e9851c9
Autor:
Byung Jo Choi, Min Hee Park, Kang Ho Park, Wan Hui Han, Hee Ji Yoon, Hye Yoon Jung, Ju Yeon Hong, Md Riad Chowdhury, Kyung Yeol Kim, Jihoon Lee, Im-Sook Song, Minyeong Pang, Min-Koo Choi, Erich Gulbins, Martin Reichel, Johannes Kornhuber, Chang-Won Hong, Changho Kim, Seung Hyun Kim, Edward H. Schuchman, Hee Kyung Jin, Jae-sung Bae
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Acid sphingomyelinase (ASM) is a sphingolipid metabolizing enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide, and previous work has shown it is upregulated in models of Alzheimer’s disease. Here the authors demonstrate in a mouse mo
Externí odkaz:
https://doaj.org/article/52c99cf51ae64f39b52ec19ee7f53cf4
Publikováno v:
Poultry Science, Vol 101, Iss 6, Pp 101852- (2022)
ABSTRACT: This research was conducted to determine the effects Achyranthes japonica extract (AJE) supplementation to corn-soybean meal-wheat-based diet on the growth performance, nutrient digestibility, cecal microflora, excreta noxious gas emission,
Externí odkaz:
https://doaj.org/article/6b928fd80d144bf3966e0354ee85d587
Publikováno v:
Pharmaceuticals, Vol 16, Iss 6, p 802 (2023)
Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via multiple intracellular interactions, generating reactive oxygen species and DNA-adducted configurations that induce apoptosis, topoisomerase II inhibition, and histo
Externí odkaz:
https://doaj.org/article/8ca1fc05de3d4d158421e7da2ee4d3f0
Autor:
Ju Youn Lee, Seung Hoon Han, Min Hee Park, Im-Sook Song, Min-Koo Choi, Eunsoo Yu, Cheol-Min Park, Hee-Jin Kim, Seung Hyun Kim, Edward H. Schuchman, Hee Kyung Jin, Jae-sung Bae
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Neuronal sphingosine kinase 1 (SphK1) acetylates COX2 which is needed for microglial phagocytosis activity, and release of pro-resolving mediators (SPMs) from neurons. Here the authors examine how SphK1-mediates COX2 acetylation, and how this leads t
Externí odkaz:
https://doaj.org/article/3035df8592594ac98f3be370c56a59d8
Autor:
Min-Koo Choi, Sojeong Jin, Ji-Hyeon Jeon, Woo Youl Kang, Sook Jin Seong, Young-Ran Yoon, Yong-Hae Han, Im-Sook Song
Publikováno v:
Journal of Ginseng Research, Vol 44, Iss 2, Pp 229-237 (2020)
Background: We investigated the tolerability and pharmacokinetic properties of various ginsenosides, including Rb1, Rb2, Rc, Rd, and compound K, after single or multiple administrations of red ginseng extract in human beings. Methods: Red ginseng ext
Externí odkaz:
https://doaj.org/article/979ee5ff98454807938bc493ceac3044
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1896 (2022)
With the increased frequency of red ginseng extract (RGE) and lactic acid bacteria (LAB) co-administration, we aimed to investigate the interactions between RGE and LAB with regard to in vitro and in vivo deglycosylation metabolism and the pharmacoki
Externí odkaz:
https://doaj.org/article/0bc65952dbbf47a5b3cac0ecf92eb120
Autor:
So-Yeon Jeon, Ji-Hyeon Jeon, Jin-Hyang Park, Jihoon Lee, Minyeong Pang, Min-Koo Choi, Im-Sook Song
Publikováno v:
Toxics, Vol 10, Iss 10, p 576 (2022)
Fimasartan, amlodipine, and hydrochlorothiazide are commonly used in combination therapies as antihypertensive drugs. This study aimed to develop and validate an analytical method for fimasartan, its active and major metabolite fimasartan-amide, amlo
Externí odkaz:
https://doaj.org/article/083e1b976ce444928de9ed3fb7cc9a63