Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Min‐Hwan Kim"'
Publikováno v:
Journal of Ginseng Research, Vol 48, Iss 4, Pp 417-424 (2024)
Background: This research main objective was to evaluate a proliposomes (PLs) formulation for the enhancement of oral bioavailability of ginsenosides, using ginsenoside Rg3 (Rg3) as a marker. Methods: A novel PLs formulation was prepared using a modi
Externí odkaz:
https://doaj.org/article/f6cc42d7d3434734afe32b0bd10c0e01
Autor:
SeungRee Seo, Gwan-Young Kim, Min-Hwan Kim, Kyung Won Lee, Min-Jae Kim, Mansingh Chaudhary, Khadka Bikram, Taeheon Kim, Seungmok Choi, Heejin Yang, Joo Won Park, Dae-Duk Kim, Ki-Taek Kim
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 1033 (2024)
Despite the various therapeutic benefits and high tolerance of orally administered silybin, poor water-solubility can be the main restrictive physicochemical feature, which results in low oral bioavailability in the absorption. A milk thistle nanocry
Externí odkaz:
https://doaj.org/article/94c7156034f142d19c108d42906b4e15
Autor:
Chun‐Bong Synn, Sung Eun Kim, Hee Kyu Lee, Min‐Hwan Kim, Jae Hwan Kim, Ji Min Lee, Ha Ni Jo, Wongeun Lee, Dong Kwon Kim, Youngseon Byeon, Young Seob Kim, Mi Ran Yun, Chae‐Won Park, Jiyeon Yun, Sangbin Lim, Seong Gu Heo, San‐Duk Yang, Eun Ji Lee, Seul Lee, Hunmi Choi, You Won Lee, Jae Seok Cho, Do Hee Kim, Sungho Park, Jung‐Ho Kim, Yewon Choi, Sung Sook Lee, Beung‐Chul Ahn, Chang Gon Kim, Sun Min Lim, Min Hee Hong, Hye Ryun Kim, Kyoung‐Ho Pyo, Byoung Chul Cho
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives AXL‐mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti‐tumor and anti‐metastatic activities of SKI‐G‐801, a sma
Externí odkaz:
https://doaj.org/article/2810ccf729dc4cf68402dc5c21aa1ea6
Publikováno v:
Biomolecules, Vol 13, Iss 1, p 131 (2023)
Poly(3-hydroxybutyrate) (PHB) is a versatile thermoplastic with superior biodegradability and biocompatibility that is intracellularly accumulated by numerous bacterial and archaeal species. Priestia sp. strain JY310 that was able to efficiently biot
Externí odkaz:
https://doaj.org/article/e0e12a9583b743349538dd6ca63e63d1
Autor:
Ki-Taek Kim, Min-Hwan Kim, Ju-Hwan Park, Jae-Young Lee, Hyun-Jong Cho, In-Soo Yoon, Dae-Duk Kim
Publikováno v:
Journal of Ginseng Research, Vol 42, Iss 4, Pp 512-523 (2018)
Background: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is require
Externí odkaz:
https://doaj.org/article/3a44bbefb0224123b5f44c39efd904eb
Autor:
Ki-Taek Kim, Joon Lee, Min-Hwan Kim, Ju-Hwan Park, Jae-Young Lee, Joo-Hyun Song, Minwoong Jung, Myoung-Hoon Jang, Hyun-Jong Cho, In-Soo Yoon, Dae-Duk Kim
Publikováno v:
Drug Delivery, Vol 24, Iss 1, Pp 1204-1215 (2017)
Topical and transdermal drug delivery has great potential in non-invasive and non-oral administration of poorly bioavailable therapeutic agents. However, due to the barrier function of the stratum corneum, the drugs that can be clinically feasible ca
Externí odkaz:
https://doaj.org/article/4a95621d9a854b8ebcc489a223305883
Autor:
Min-Hwan Kim, Ju-Hwan Park, Duy-Thuc Nguyen, Sungyun Kim, Da In Jeong, Hyun-Jong Cho, Dae-Duk Kim
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 170 (2021)
Hyaluronidase (HAase) inhibitor-incorporated hyaluronic acid (HA) hydrogel cross-linked with 1,4-butanediol diglycidyl ether (BDDE) was designed to reduce the toxicity risk induced by BDDE and its biodegradation rate in subcutaneous tissue. The formu
Externí odkaz:
https://doaj.org/article/4eca7a54c8894f0dbc678d937906c129
Autor:
Min-Hwan Kim, Yae-Eun Jeon, Soobeen Kang, Jae-Young Lee, Ki Won Lee, Ki-Taek Kim, Dae-Duk Kim
Publikováno v:
Pharmaceutics, Vol 12, Iss 9, p 845 (2020)
Orobol is one of the major soy isoflavones, and has been reported to have various pharmacological activities, including an anti-skin-aging effect. However, since it has low solubility in water and physicochemical instability, the formulation of orobo
Externí odkaz:
https://doaj.org/article/3b4a66bb8fb54823bf02e9835202fca0
Autor:
Min-Hwan Kim, Dong Hyun Kim, Duy-Thuc Nguyen, Han Sol Lee, Nae-Won Kang, Min-Jun Baek, Jiseon An, So-Yeol Yoo, Yong-Hyeon Mun, Wonhwa Lee, Ki-Taek Kim, Cheong-Weon Cho, Jae-Young Lee, Dae-Duk Kim
Publikováno v:
Pharmaceutics, Vol 12, Iss 8, p 718 (2020)
PEGylated Eudragit L100 (ELP)-containing proliponiosomes (PLNs) were developed for improved oral delivery of celecoxib (CXB). The successful introduction of PEG 2000 or 5000 to Eudragit L100 (EL) was confirmed via proton nuclear magnetic resonance an
Externí odkaz:
https://doaj.org/article/224872e91df64a208b24f395fedc70bd
Autor:
Nae-Won Kang, Jae-Young Lee, Kwangho Song, Min-Hwan Kim, Soyeon Yoon, Duy-Thuc Nguyen, Sungho Kim, Yeong Shik Kim, Dae-Duk Kim
Publikováno v:
Molecules, Vol 25, Iss 8, p 1774 (2020)
Recently, potent neuroprotective and anti-diabetic effects of 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN), a sesquiterpenoid isolated from Tussilago farfara Linnaeus, have been elucidated. To facilitat
Externí odkaz:
https://doaj.org/article/14f4d4d194a34257a704264db51b0a5b