Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mimi C, Sammarco"'
Autor:
Xue Xiao, Conan Juan, Tingsheng Drennon, Cedric R. Uytingco, Neda Vishlaghi, Dimitri Sokolowskei, Lin Xu, Benjamin Levi, Mimi C. Sammarco, Robert J. Tower
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Self-renewal and differentiation of skeletal stem and progenitor cells (SSPCs) are tightly regulated processes, with SSPC dysregulation leading to progressive bone disease. While the application of single-cell RNA sequencing (scRNAseq) to th
Externí odkaz:
https://doaj.org/article/139c56a9dedf4675ba5ce8807176a3d4
Autor:
Josue Jaramillo, Caroline Taylor, Rachel McCarley, Melissa Berger, Emily Busse, Mimi C. Sammarco
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Cell metabolism coordinates the biochemical reactions that produce carbon and ATP in order for the cell to proliferate, differentiate, and respond to environmental changes. Cell type determines metabolic demand, so proliferating skeletal progenitors
Externí odkaz:
https://doaj.org/article/808f674fee1e4100b0301ee2dc96991e
Autor:
Robert J Tower, Emily Busse, Josue Jaramillo, Michelle Lacey, Kevin Hoffseth, Anyonya R Guntur, Jennifer Simkin, Mimi C Sammarco
Publikováno v:
eLife, Vol 11 (2022)
De novo limb regeneration after amputation is restricted in mammals to the distal digit tip. Central to this regenerative process is the blastema, a heterogeneous population of lineage-restricted, dedifferentiated cells that ultimately orchestrates r
Externí odkaz:
https://doaj.org/article/2a598576685044ffb8c6917409c773c1
Autor:
Kevin Hoffseth, Emily Busse, Josue Jaramillo, Jennifer Simkin, Michelle Lacey, Mimi C. Sammarco
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones, and tendons, all of which rege
Externí odkaz:
https://doaj.org/article/02439c29627e4ba285ed252a6e6a940c
Autor:
Joseph P. Hoffmann, Jessica K. Friedman, Yihui Wang, James B. McLachlan, Mimi C. Sammarco, Lisa A. Morici, Chad J. Roy
Publikováno v:
Frontiers in Microbiology, Vol 10 (2020)
Increased prevalence of antibiotic resistance in skin and soft tissue infections is a concerning public health challenge currently facing medical science. A combinatory, broad spectrum biocidal antiseptic has been developed (“ASP”) as a topically
Externí odkaz:
https://doaj.org/article/cf3afcab25b2431da8b68c20f296d889
Autor:
Emily Busse, Cheryl Hickey, Nicole Vasilakos, Kennon Stewart, Fred O'Brien, Jessica Rivera, Luis Marrero, Michelle Lacey, Rebecca Schroll, Keith Van Meter, Mimi C Sammarco
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0244236 (2020)
Military literature has demonstrated the utility and safety of tourniquets in preventing mortality for some time, paving the way for increased use of tourniquets in civilian settings, including perioperatively to provide a bloodless surgical field. H
Externí odkaz:
https://doaj.org/article/73403a5e5a8d4ed9a88ed17ec0b4abcd
Autor:
Mimi C Sammarco, Jennifer Simkin, Alexander J Cammack, Danielle Fassler, Alexej Gossmann, Luis Marrero, Michelle Lacey, Keith Van Meter, Ken Muneoka
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140156 (2015)
Oxygen is critical for optimal bone regeneration. While axolotls and salamanders have retained the ability to regenerate whole limbs, mammalian regeneration is restricted to the distal tip of the digit (P3) in mice, primates, and humans. Our previous
Externí odkaz:
https://doaj.org/article/ee60b869acaa45529983dd55a8a83cac
Publikováno v:
J Biomech
The mouse digit tip amputation model is an excellent model of bone regeneration, but its size and shape present an obstacle for biomechanical testing. As a result, assessing the structural quality of the regenerated bone in this model has focused on
Autor:
Mimi C. Sammarco, Emily Busse, Jennifer Simkin, Michelle Lacey, Kevin F. Hoffseth, Josue Jaramillo
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Mouse digit amputation provides a useful model of bone growth after injury, in that the injury promotes intramembranous bone formation in an adult animal. The digit tip is composed of skin, nerves, blood vessels, bones, and tendons, all of which rege