Genomic insights from a deeply phenotyped highly consanguineous neurodevelopmental disorders cohort.

Autor: Akter H; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh; Laboratory of Population Genetics, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh., Rahaman MA; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Eshaque TB; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Mohamed N; Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, UAE., Islam A; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh; GenomeArc Inc., Mississauga, ON, Canada., Morshed M; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Shahin Z; Imperial College London, London, United Kingdom., Muhaimin A; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Foyzullah AM; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Mim RA; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Omar FB; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Hasan MN; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh; GenomeArc Inc., Mississauga, ON, Canada., Satsangi D; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Ahmed N; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Al Saba A; Laboratory of Population Genetics, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh., Jahan N; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Hossen MA; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Mondol MA; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Sakib AS; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Kabir R; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Jahan Chowdhury MS; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Shams N; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Afroz S; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Kanta SI; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Bhuiyan SJ; Pediatric neurology. Evercare Hospital, Dhaka, Bangladesh., Biswas R; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Hanif S; Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, UAE., Tambi R; Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, UAE., Nassir N; Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, UAE; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Rahman MM; Department of Paediatric Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh., Duan J; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Department of Biomedicine and the iSEQ Centre, Aarhus University, Aarhus, Denmark; Center for Genomics and Personalized Medicine, Aarhus, Denmark., D Børglum A; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark; Department of Biomedicine and the iSEQ Centre, Aarhus University, Aarhus, Denmark; Center for Genomics and Personalized Medicine, Aarhus, Denmark., Amin R; Ministry of Health and Family Welfare, Government of People Republic of Bangladesh, Dhaka, Bangaldesh., Basiruzzaman M; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh., Kamruzzaman M; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Sarker S; Centre for Precision Therapeutics (NPT), NeuroGen Healthcare, Dhaka, Bangladesh; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Woodbury-Smith M; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Uddin KMF; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh; Department of Biochemistry, Holy Family Red Crescent Medical College, Dhaka, Bangladesh., Nabi AHMN; Laboratory of Population Genetics, Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh., Uddin M; Center for Applied and Translational Genomics, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai Health, Dubai, UAE; GenomeArc Inc., Mississauga, ON, Canada; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE. Electronic address: dafil.mohammed@genomearc.com.

Publikováno v: Genetics in medicine : official journal of the American College of Medical Genetics [Genet Med] 2024 Sep 26; Vol. 27 (1), pp. 101282. Date of Electronic Publication: 2024 Sep 26.

Mutational spectrum and phenotypic variability of Duchenne muscular dystrophy and related disorders in a Bangladeshi population.

Autor: Sarker S; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh.; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Eshaque TB; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Soorajkumar A; Center for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Nassir N; Center for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Zehra B; Center for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE., Kanta SI; Bangladesh Shishu Hospital and Institute, Dhaka, Bangladesh., Rahaman MA; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Islam A; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh.; GenomeArc Inc., Mississauga, Ontario, Canada., Akter S; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Ali MK; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Mim RA; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Uddin KMF; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Chowdhury MSJ; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Shams N; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Baqui MA; Department of Biochemistry, Holy Family Red Crescent Medical College and Hospital, Dhaka, Bangladesh., Lim ET; Department of Genomics and Computational Biology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA.; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, 01605, USA., Akter H; Genetics and Genomic Medicine Centre (GGMC), NeuroGen Healthcare, Dhaka, Bangladesh., Woodbury-Smith M; Biosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK. marc.woodbury-smith@newcastle.ac.uk., Uddin M; Center for Applied and Translational Genomics (CATG), Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, UAE. mohammed.uddin@mbru.ac.ae.; GenomeArc Inc., Mississauga, Ontario, Canada. mohammed.uddin@mbru.ac.ae.

Publikováno v: Scientific reports [Sci Rep] 2023 Dec 06; Vol. 13 (1), pp. 21547. Date of Electronic Publication: 2023 Dec 06.