Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Miluše Hertlová"'
Autor:
Jurg Ott, Miluše Hertlová, Lukáš Pácal, Lydie IzakovičováHollá, Michal Beránek, Anna Vašků, Svatava Tschöplová, Darja Krusová, Sandra Barral, Andrea Stejskalová, Kateřina Kaňková
Publikováno v:
Diabetologia. 50:990-999
In the present study we investigated potential associations of a set of 45 single nucleotide polymorphisms (SNP) in 20 candidate genes on eight chromosomes with diabetic nephropathy (DN) in type 2 diabetes mellitus. We aimed to compare two methodolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebfac19be842c133c070d92811fe408
https://doi.org/10.1007/s00125-007-0606-3
https://doi.org/10.1007/s00125-007-0606-3
Publikováno v:
Nephrology Dialysis Transplantation. 20:1093-1102
Background. Diabetic nephropathy (DN) represents a devastating complication of diabetes. Family clustering, heterogeneity in the onset and progression and results of segregation studies indicate that susceptibility to DN is a complex trait. Methods.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b7375d4013ff7e47e0389dd617e9dd
https://doi.org/10.1093/ndt/gfh711
https://doi.org/10.1093/ndt/gfh711
Autor:
Jindřich Olšovský, Darja Krusová, Miluše Hertlová, Marta Kalousová, Kateřina Kaňková, Tomáš Zima
Publikováno v:
Archives of physiology and biochemistry. 114(2)
Diabetes mellitus, especially when complicated with decline of renal function due to diabetic nephropathy (DN), is associated with accumulation of advanced glycation end products (AGEs) exerting their adverse effects via receptor of AGE (RAGE). Solub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c989a0748679845134635b39b09ca90b
https://pubmed.ncbi.nlm.nih.gov/18615900
https://pubmed.ncbi.nlm.nih.gov/18615900
Publikováno v:
Annals of the New York Academy of Sciences. 1043:919-919
We found significant association of selected genetic variants in the RAGE, SOD2 and PARP-1 genes with the presence of DN in type 2 diabetics and, in the case of RAGE and PARP-1, also with acceleration of DN onset. We therefore conclude that those htS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbb30199bced4a89fdd8f36f0b67d849
https://doi.org/10.1196/annals.1333.133
https://doi.org/10.1196/annals.1333.133