Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Milton R, Brown"'
Autor:
Camilla Margaroli, Hamed Horati, Luke W. Garratt, Vincent D. Giacalone, Craig Schofield, A. Susanne Dittrich, Tim Rosenow, Brian S. Dobosh, Hong S. Lim, Dario L. Frey, Mieke Veltman, George L. Silva, Milton R. Brown, Carsten Schultz, Harm A.W.M. Tiddens, Sarath Ranganathan, Joshua D. Chandler, Peng Qiu, Limin Peng, Bob J. Scholte, Marcus A. Mall, Anthony Kicic, Lokesh Guglani, Stephen M. Stick, Hettie M. Janssens, Rabindra Tirouvanziam
Publikováno v:
Journal of Cystic Fibrosis, 21(6), 967-976. Elsevier
Background: Macrophages are the major resident immune cells in human airways coordinating responses to infection and injury. In cystic fibrosis (CF), neutrophils are recruited to the airways shortly after birth, and actively exocytose damaging enzyme
Autor:
Vincent D, Giacalone, Diego, Moncada-Giraldo, Camilla, Margaroli, Milton R, Brown, George L, Silva, Joshua D, Chandler, Limin, Peng, Rabindra, Tirouvanziam, Lokesh, Guglani
Publikováno v:
Pediatric Pulmonology. 57:2189-2198
In this pilot study, we investigated whether induced sputum (IS) could serve as a viable alternative to bronchoalveolar lavage (BAL) and yield robust inflammatory biomarkers in toddlers with cystic fibrosis (CF) featuring minimal structural lung dise
Autor:
Jervaughn Hunter, Donald Bejleri, Michael Davis, Joshua T. Maxwell, Matthew Robeson, Milton R. Brown, Benjamin W. Streeter, Olga Brazhkina, Karen L. Christman, Hyun Ji Park
Publikováno v:
Biomater Sci
Pediatric patients with congenital heart defects (CHD) often present with heart failure from increased load on the right ventricle (RV) due to both surgical methods to treat CHD and the disease itself. Patients with RV failure often require transplan
Autor:
Osric A Forrest, Brian Dobosh, Sarah A Ingersoll, Sanjana Rao, Alexander Rojas, Julie Laval, Jessica A Alvarez, Milton R Brown, Vin Tangpricha, Rabindra Tirouvanziam
Publikováno v:
Journal of leukocyte biologyREFERENCES. 112(4)
Cystic fibrosis (CF) airways feature high extracellular levels of the IL-1 family of proinflammatory mediators. These mediators are cleavage products of caspase-1, the final protease in the inflammasome cascade. Due to the proven chronic presence of
Autor:
Marcus A. Mall, Luke W. Garratt, Hettie M. Janssens, Hamed Horati, Dario L. Frey, Camilla Margaroli, Stephen M. Stick, Tim Rosenow, Rabindra Tirouvanziam, Milton R. Brown, Lokesh Guglani, Bob J. Scholte, A. Susanne Dittrich, Limin Peng, Carsten Schultz, Anthony Kicic, Samuel T. Montgomery
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 199(7), 873-881. American Thoracic Society
American Journal of Respiratory and Critical Care Medicine
American Journal of Respiratory and Critical Care Medicine
Rationale: Neutrophils are recruited to the airways of individuals with cystic fibrosis (CF). In adolescents and adults with CF, airway neutrophils actively exocytose the primary granule protease elastase (NE), whose extracellular activity correlates
Autor:
Limin Peng, Yael Gernez, Daniel M. Chopyk, Milton R. Brown, Rabindra Tirouvanziam, Carol Conrad, Osric A. Forrest, Vin Tangpricha, Richard B. Moss
Publikováno v:
Journal of Cystic Fibrosis. 18:64-70
Background Resistin is an immunometabolic mediator that is elevated in several inflammatory disorders. A ligand for Toll-like receptor 4, resistin modulates the recruitment and activation of myeloid cells, notably neutrophils. Neutrophils are major d
Autor:
Robin S. Scott, Charmian A. Quigley, Sreekumar G Pillai, Ying Grace Li, John S. Parks, Milton R. Brown, Poulabi Banerjee, Werner F. Blum
Publikováno v:
Hormone Research in Paediatrics. 91:164-174
Background/Aims: The term idiopathic short stature (ISS) describes short stature of unknown, but likely polygenic, etiology. This study aimed to identify genetic polymorphisms associated with the ISS phenotype, and with growth response to supplementa
Autor:
Diego Moncada Giraldo, Limin Peng, Rabindra Tirouvanziam, Bijean D Ford, Camilla Margaroli, Milton R. Brown, Vincent D. Giacalone
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2530, p 2530 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 5
International Journal of Molecular Sciences
Volume 22
Issue 5
Cystic fibrosis (CF) lung disease is dominated by the recruitment of myeloid cells (neutrophils and monocytes) from the blood which fail to clear the lung of colonizing microbes. In prior in vitro studies, we showed that blood neutrophils migrated th
Distinct compartmentalization of immune cells and mediators characterizes bullous pemphigoid disease
Autor:
Milton R. Brown, Lopa Bhatt, Sanjeev Ahuja, Ron J. Feldman, Eric Springman, Vincent D. Giacalone, Camilla Margaroli, Cecilia Thompson, Bridget Bradley, Benjamin K. Stoff, Rabindra Tirouvanziam
Publikováno v:
Experimental dermatologyREFERENCES. 29(12)
Bullous pemphigoid (BP) is an autoimmune blistering disease characterized by recruitment of leucocytes into skin and release of damaging enzymes, resulting in epidermal detachment and blister formation. To better understand the role of leukotriene B4
Autor:
David Trac, Daniel I Jacobs, Carly Zaladonis, Martin L Li, Emily Baker, Milton R. Brown, Joshua T. Maxwell, Michael Davis, Ming Shen
Publikováno v:
Circulation Research. 125
Nearly 1% of babies born in the US will be diagnosed with a congenital heart defect (CHD). While surgical therapy has improved survival, many of these children go on to develop right ventricular heart failure (RVHF). The emergence of cardiovascular r