Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Milton M. Perlmutter"'
Autor:
Milton M. Perlmutter, Charna H. K. Nissenson, A. Luxen, Michael E. Phelps, Jorge R. Barrio, William P. Melega
Publikováno v:
Biochemical Pharmacology. 39:1853-1860
In vivo double-label experiments in rats were designed to correlate the peripheral and cerebral metabolism of 6-[18F]fluoro-L-DOPA [( 18F]FDOPA) with that of [3H]L-DOPA. Authentic samples of the major [18F]FDOPA metabolites were synthesized to identi
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes. 41:801-807
4-[18F]Fluoro-L-m-tyrosine (6), a new analog of L-dopa for probing the presynaptic dopaminergic system by positron emission tomography has been synthesized in good radiochemical yields via the regioselective fluorodemercuration of the 4-mercurio deri
Autor:
Milton M. Perlmutter, Joseph S. Cook, Michael E. Phelps, A. Luxen, Gerald Bida, Jorge R. Barrio, Glenn Van Moffaert, N. Satyamurthy
Publikováno v:
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes. 41(3)
Regioselective radiofluorodemercuration of the 6-mercurio derivative 5 with [ 18 F]acetylhypofluorite afforded, after acidic hydrolysis, 6-[ 18 F]fluoro- l -3,4-dihydroxyphenylalanine (6-FD, 1 ) with a radiochemical yield of 11% (decay corrected and
Publikováno v:
Carbohydrate Research. 155:107-118
The reaction of 1,2-anhydro-3,4:5,6-di-O-isopropylidene-1-C-nitro-d-mannitol (2) with potassium hydrogenfluoride in ethylene glycol under anhydrous conditions provides a route to 2-deoxy-2-fluoro-d-glucose, the 18F-labeled analog of which is an impor
Autor:
Scott T. Grafton, André Luxen, Michael E. Phelps, William P. Melega, Milton M. Perlmutter, Sung-Cheng Huang, Jorge R. Barrio, Charna H. K. Nissenson
Publikováno v:
Journal of Neurochemistry. 53:311-314
4-[18F]Fluoro-L-m-tyrosine (FMT), a biochemical probe of striatal dopaminergic function, has been synthesized as an L-3,4-di-hydroxyphenylalanine analog for positron emission tomography. Biochemical characterization of this compound in the rat 30 min
Publikováno v:
Canadian Journal of Chemistry. 62:2709-2711
Publikováno v:
Chemischer Informationsdienst. 14
The reaction of KHF2 with 1,2-anhydro-3,4- : 5,6-di-O-isopropylidene-1-C-nitro-D-mannitol (4) provides a rapid, stereospecific route to 2-deoxy-2-fluoro-D-glucose (2), the 18F-labelled analogue of which, (1), is an important radiopharmaceutical of us
Publikováno v:
ChemInform. 18
The reaction of 1,2-anhydro-3,4:5,6-di-O-isopropylidene-1-C-nitro-d-mannitol (2) with potassium hydrogenfluoride in ethylene glycol under anhydrous conditions provides a route to 2-deoxy-2-fluoro-d-glucose, the 18F-labeled analog of which is an impor
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:465-466
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 26:1-2