Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Milovan, Suvakov"'
Autor:
Vivekananda Sarangi, Yeongjun Jang, Milovan Suvakov, Taejeong Bae, Liana Fasching, Shobana Sekar, Livia Tomasini, Jessica Mariani, Flora M Vaccarino, Alexej Abyzov
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1009487 (2022)
Accurate discovery of somatic mutations in a cell is a challenge that partially lays in immaturity of dedicated analytical approaches. Approaches comparing a cell's genome to a control bulk sample miss common mutations, while approaches to find such
Externí odkaz:
https://doaj.org/article/848e1df22c1148058be996edd1e34985
Autor:
Taejeong, Bae, Liana, Fasching, Yifan, Wang, Joo Heon, Shin, Milovan, Suvakov, Yeongjun, Jang, Scott, Norton, Caroline, Dias, Jessica, Mariani, Alexandre, Jourdon, Feinan, Wu, Arijit, Panda, Reenal, Pattni, Yasmine, Chahine, Rebecca, Yeh, Rosalinda C, Roberts, Anita, Huttner, Joel E, Kleinman, Thomas M, Hyde, Richard E, Straub, Christopher A, Walsh, Alexander E, Urban, James F, Leckman, Daniel R, Weinberger, Flora M, Vaccarino, Sirisha, Pochareddy
Publikováno v:
Science. 377:511-517
We analyzed 131 human brains (44 neurotypical, 19 with Tourette syndrome, 9 with schizophrenia, and 59 with autism) for somatic mutations after whole genome sequencing to a depth of more than 200×. Typically, brains had 20 to 60 detectable single-nu
Autor:
Arijit Panda, Milovan Suvakov, Jessica Mariani, Kristen L. Drucker, Yohan Park, Yeongjun Jang, Thomas M. Kollmeyer, Gobinda Sarkar, Taejeong Bae, Jean J. Kim, Wan Hee Yoon, Robert B. Jenkins, Flora Vaccarino, Alexej Abyzov
Publikováno v:
CRISPR J
The CRISPR-Cas9 system has enabled researchers to precisely modify/edit the sequence of a genome. A typical editing experiment consists of two steps: (i) editing cultured cells; (ii) cell cloning and selection of clones with and without intended edit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebeb2d023ff9339d6536483607dbf596
https://doi.org/10.1101/2022.05.17.492193
https://doi.org/10.1101/2022.05.17.492193
Autor:
Alexandre Jourdon, Feinan Wu, Jessica Mariani, Davide Capauto, Scott Norton, Livia Tomasini, Anahita Amiri, Milovan Suvakov, Jeremy D. Schreiner, Yeongjun Jang, Arijit Panda, Cindy Khanh Nguyen, Elise M. Cummings, Gloria Han, Kelly Powell, Anna Szekely, James C. McPartland, Kevin Pelphrey, Katarzyna Chawarska, Pamela Ventola, Alexej Abyzov, Flora M. Vaccarino
SummaryThere is no clear genetic etiology or convergent pathophysiology for autism spectrum disorders (ASD). Using cortical organoids and single-cell transcriptomics, we modeled alterations in the formation of the forebrain between sons with idiopath
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de719f693357e8358798f4c1bc3bc59e
https://doi.org/10.1101/2022.03.19.484988
https://doi.org/10.1101/2022.03.19.484988
Autor:
Vivekananda Sarangi, Yeongjun Jang, Milovan Suvakov, Taejeong Bae, Liana Fasching, Shobana Sekar, Livia Tomasini, Jessica Mariani, Flora M. Vaccarino, Alexej Abyzov
Publikováno v:
PLoS computational biology. 18(4)
Accurate discovery of somatic mutations in a cell is a challenge that partially lays in immaturity of dedicated analytical approaches. Approaches comparing a cell’s genome to a control bulk sample miss common mutations, while approaches to find suc
Autor:
Vivekananda Sarangi, Yeongjun Jang, Milovan Suvakov, Taejeong Bae, Liana Fasching, Shobana Sekar, Livia Tomasini, Jessica Mariani, Flora M. Vaccarino, Alexej Abyzov
Publikováno v:
PLOS Computational Biology. 18:e1010703