Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Milosz, Gruca"'
Autor:
Krzysztof Guzik, Krzysztof Pyrc, Milosz Gruca, Karolina Plaza, Jan Smagur, Slawomir Zeglen, Marek Ochman, Tomasz Kantyka, Jan Potempa
Publikováno v:
Journal of Innate Immunity. 5:251-260
The pulmonary surfactant is a complex mixture of lipids and proteins that is important for respiratory lung functions, which also provides the first line of innate immune defense. Pulmonary surfactant protein-A (SP-A) is a major surfactant component
Autor:
Matthias Bochtler, Aneta Oleksy, Renata Filipek, Malgorzata Rzychon, Jan Potempa, Milosz Gruca, Adam Dubin
Publikováno v:
Journal of Biological Chemistry. 278:40959-40966
Staphostatins are the endogenous inhibitors of the major secreted cysteine proteases of Staphylococcus aureus, the staphopains. Our recent crystal structure of staphostatin B has shown that this inhibitor forms a mixed, eight-stranded β-barrel with
Autor:
Lukasz Magiera, Jan Potempa, Jan Smagur, Małgorzata Bzowska, Krzysztof Guzik, Ida B. Thøgersen, Milosz Gruca, Jan J. Enghild
Publikováno v:
J Innate Immun
Smagur, J, Guzik, K, Magiera, L, Bzowska, M, Gruca, M, Thøgersen, I B, Enghild, J J & Potempa, J 2009, ' A new pathway of staphylococcal pathogenesis : Apoptosis-like death induced by staphopain B in human neutrophils and monocytes ', Journal of Innate Immunity, vol. 1, no. 2, pp. 98-108 . https://doi.org/10.1159/000181014
Smagur, J, Guzik, K, Magiera, L, Bzowska, M, Gruca, M, Thøgersen, I B, Enghild, J J & Potempa, J 2009, ' A new pathway of staphylococcal pathogenesis : Apoptosis-like death induced by staphopain B in human neutrophils and monocytes ', Journal of Innate Immunity, vol. 1, no. 2, pp. 98-108 . https://doi.org/10.1159/000181014
Circulating neutrophils and monocytes form the first line of cellular defense against invading bacteria. Here, we describe a novel and specific mechanism of disabling and eliminating phagocytes by Staphylococcus aureus. Staphopain B (SspB) selectivel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaaad3c0f41e7a257d2933c7d12e6333
https://ruj.uj.edu.pl/xmlui/handle/item/66535
https://ruj.uj.edu.pl/xmlui/handle/item/66535
Publikováno v:
Biological chemistry. 388(4)
Of seven human cystatins investigated, none inhibited the cysteine proteases staphopain A and B secreted by the human pathogen Staphylococcus aureus. Rather, the extracellular cystatins C, D and E/M were hydrolyzed by both staphopains. Based on MALDI
Autor:
Renata, Filipek, Malgorzata, Rzychon, Aneta, Oleksy, Milosz, Gruca, Adam, Dubin, Jan, Potempa, Matthias, Bochtler
Publikováno v:
The Journal of biological chemistry. 278(42)
Staphostatins are the endogenous inhibitors of the major secreted cysteine proteases of Staphylococcus aureus, the staphopains. Our recent crystal structure of staphostatin B has shown that this inhibitor forms a mixed, eight-stranded beta-barrel wit