Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Milos Budesinsky"'
Publikováno v:
Molecules, Vol 28, Iss 9, p 3794 (2023)
Aliphatic hydrocarbons (HCs) are usually analyzed by gas chromatography (GC) or matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. However, analyzing long-chain HCs by GC is difficult because of their low volatility and the risk o
Externí odkaz:
https://doaj.org/article/73cd8bbf52bf47baa8066172f60ee496
Publikováno v:
Molecules, Vol 27, Iss 21, p 7639 (2022)
The synthesis of a tetrathiafulvalene (TTF) derivative, S-[4-({4-[(2,2′-bi-1,3-dithiol-4-ylmethoxy)methyl] phenyl}ethynyl)phenyl] ethanethioate, suitable for the modification of gold nanoparticles (AuNPs), is described in this article. The TTF liga
Externí odkaz:
https://doaj.org/article/e457cfb2a3dc4cf49e57ee26114afff4
Autor:
Silvie Rimpelová, Michal Jurášek, Lucie Peterková, Jiří Bejček, Vojtěch Spiwok, Miloš Majdl, Michal Jirásko, Miloš Buděšínský, Juraj Harmatha, Eva Kmoníčková, Pavel Drašar, Tomáš Ruml
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 15, Iss 1, Pp 1933-1944 (2019)
Sesquiterpene lactones are secondary plant metabolites with sundry biological effects. In plants, they are synthesized, among others, for pesticidal and antimicrobial effects. Two such compounds, archangelolide and trilobolide of the guaianolide type
Externí odkaz:
https://doaj.org/article/e0555971933f45a6b2c7b8b8a83ca8e5
Autor:
Eva Harazim, Vladimír Vrkoslav, Miloš Buděšínský, Petr Harazim, Martin Svoboda, Richard Plavka, Zuzana Bosáková, Josef Cvačka
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 11, Pp 2164-2173 (2018)
Vernix caseosa, the waxy substance that coats the skin of newborn babies, has an extremely complex lipid composition. We have explored these lipids and identified nonhydroxylated 1-O-acylceramides (1-O-ENSs) as a new class of lipids in vernix caseosa
Externí odkaz:
https://doaj.org/article/deba3aa49dac44f99533931c3a205076
Autor:
Aneta Kalužíková, Vladimír Vrkoslav, Eva Harazim, Michal Hoskovec, Richard Plavka, Miloš Buděšínský, Zuzana Bosáková, Josef Cvačka
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 8, Pp 1579-1590 (2017)
Cholesteryl esters of ω-(O-acyl)-hydroxy FAs (Chl-ωOAHFAs) were identified for the first time in vernix caseosa and characterized using chromatography and MS. Chl-ωOAHFAs were isolated using adsorption chromatography on silica gel and magnesium hy
Externí odkaz:
https://doaj.org/article/6de145d7f13f4ce78861204b353eae45
Autor:
Ludmila Škorpilová, Silvie Rimpelová, Michal Jurášek, Miloš Buděšínský, Jana Lokajová, Roman Effenberg, Petr Slepička, Tomáš Ruml, Eva Kmoníčková, Pavel B. Drašar, Zdeněk Wimmer
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 1316-1324 (2017)
Like thapsigargin, which is undergoing clinical trials, trilobolide is a natural product with promising anticancer and anti-inflammatory properties. Similar to thapsigargin, it has limited aqueous solubility that strongly reduces its potential medici
Externí odkaz:
https://doaj.org/article/95b5cb3f615e43038cb837ada69890f5
Publikováno v:
ARKIVOC, Vol 2012, Iss 4, Pp 80-99 (2011)
Externí odkaz:
https://doaj.org/article/ef3389bfeb884a1eb4bffd66a8e85d24
Autor:
Camilo Rojas, Reiji Tsukamoto, Daniel Bím, Tibor András Rokob, Takashi Tsukamoto, Zora Novakova, Gabriel Kabarriti, Cyril Barinka, Lubomír Rulíšek, Niyada Hin, Lucia Motlova, Dana Ferraris, Milos Budesinsky, Barbara S. Slusher, Bridget Duvall
Publikováno v:
Bioorganic & medicinal chemistry 27(2), 255-264 (2019). doi:10.1016/j.bmc.2018.11.022
Bioorganic & medicinal chemistry 27(2), 255 - 264 (2019). doi:10.1016/j.bmc.2018.11.022
A series of carbamate-based inhibitors of glutamate carboxypeptidase II (GCPII) were designed and synthesizedusing ZJ-43, N-[[[(1S)-1-carboxy-3-methylbutyl]a
A series of carbamate-based inhibitors of glutamate carboxypeptidase II (GCPII) were designed and synthesizedusing ZJ-43, N-[[[(1S)-1-carboxy-3-methylbutyl]a
Publikováno v:
European Journal of Organic Chemistry. 2017:389-396
Autor:
Eva Kudova, Hana Chodounska, Pavla Hubalkova, Vojtech Vyklicky, Santosh Kumar Adla, Martin Svoboda, Markéta Šmídková, Kristina Holubova, Eva Tloušt’ová, Karel Vales, Milos Budesinsky, Michaela Nekardova, Barbora Krausova, Barbora Slavikova, Ladislav Vyklicky
Publikováno v:
Steroids. 117:52-61
Herein, we report a new class of amide-based inhibitors (1–4) of N-methyl- d -aspartate receptors (NMDARs) that were prepared as analogues of pregnanolone sulfate (PAS) and pregnanolone glutamate (PAG) – the steroidal neuroprotective NMDAR inhibi