Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Milos B. Rokic"'
Autor:
Patrick A. Fletcher, Kosara Smiljanic, Rafael Maso Prévide, James R. Iben, Tianwei Li, Milos B. Rokic, Arthur Sherman, Steven L. Coon, Stanko S. Stojilkovic
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Understanding the physiology and pathology of an organ composed of a variety of cell populations depends critically on genome-wide information on each cell type. Here, we report single-cell transcriptome profiling of over 6,800 freshly dispersed ante
Externí odkaz:
https://doaj.org/article/70449262d98043f5872fe663ac712568
Autor:
Milos B. Rokic, Stanko S. Stojilkovic
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 7 (2013)
The occupancy of the ATP binding sites of P2X receptor (P2XR) channels causes the rapid opening of a small cation-permeable pore, followed by a gradual dilation that renders the pore permeable to large organic cations. Electrophysiologically, this ph
Externí odkaz:
https://doaj.org/article/c54ac3a9c1f14f8b86d053d639d225e3
Autor:
Rodrigo Sandoval, Bradford Hall, Elias Utreras, Patricio A. Castro, Stanko S. Stojilkovic, Ashok B. Kulkarni, Christian Gonzalez-Billault, Anita Terse, Milos B. Rokic, Pablo Lazcano, Claudio Coddou, María José Hevia
Publikováno v:
Pain
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
Artículos CONICYT
CONICYT Chile
instacron:CONICYT
The purinergic P2X2 receptor (P2X2R) is an adenosine triphosphate-gated ion channel widely expressed in the nervous system. Here, we identified a putative cyclin-dependent kinase 5 (Cdk5) phosphorylation site in the full-size variant P2X2aR (TPKH), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8fb12dc4fe5e866389b17b689281aae
https://doi.org/10.1097/j.pain.0000000000001021
https://doi.org/10.1097/j.pain.0000000000001021
Autor:
Stanko S. Stojilkovic, Claudio Coddou, Melanija Tomić, Patricio A. Castro, Milos B. Rokic, Elías Leiva-Salcedo
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1161 (2018)
International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1161
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 4; Pages: 1161
International Journal of Molecular Sciences
P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in whole-cell recordings from c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2073137aad65af2b5aca7a82ec7fad85
http://www.mdpi.com/1422-0067/19/4/1161
http://www.mdpi.com/1422-0067/19/4/1161
Autor:
Milos B. Rokic, Stanko S. Stojilkovic, Anmar Khadra, Vendula Tvrdonova, Hana Zemkova, Arthur Sherman
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 467:713-726
Allosteric modulators of ligand-gated receptor channels induce conformational changes of the entire protein that alter potencies and efficacies for orthosteric ligands, expressed as the half maximal effective concentration (EC50) and maximum current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e4d33c3361590aeaf1627ff5bf4bd0
https://doi.org/10.1007/s00424-014-1546-7
https://doi.org/10.1007/s00424-014-1546-7
Significance: The family of purinergic P2X receptors (P2XRs) is a part of ligand-gated superfamily of channels activated by extracellular adenosine-5′-triphosphate. P2XRs are present in virtually all mammalian tissues as well as in tissues of other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5d3e8e2254347babd6ad3dd1c1c644
https://europepmc.org/articles/PMC4116155/
https://europepmc.org/articles/PMC4116155/
Autor:
Vendula Tvrdonova, Stanko S. Stojilkovic, Pavlo Kuzyk, Vojtech Vavra, Hana Zemkova, Milos B. Rokic
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59411 (2013)
PLoS ONE
PLoS ONE
The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective transmembrane pore, but specific roles of vestibule amino acid residues in receptor activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce383d76169d1678cbaa0575e3a8c86
http://europepmc.org/articles/PMC3605439?pdf=render
http://europepmc.org/articles/PMC3605439?pdf=render
Autor:
Ljiljana Nikolić, Milos B. Rokic, Miodrag Nedeljkovic, Gordana Kartelija, Nataša Todorović, Joanna Zakrzewska
Publikováno v:
Biological Research. 43
The effect of extremely low frequency magnetic fields (50 Hz, 0.5 mT) - ELF-MF, on phosphate metabolism has been studied in the isolated ganglions of the garden snail Helix pomatia, after 7 and 16 days of snail exposure to ELF-MF. The influence of EL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb95faef90f127d624ddb7d487b7061e
https://doi.org/10.4067/s0716-97602010000200012
https://doi.org/10.4067/s0716-97602010000200012
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112902 (2014)
Crystallization of the zebrafish P2X4 receptor in both open and closed states revealed conformational differences in the ectodomain structures, including the dorsal fin and left flipper domains. Here, we focused on the role of these domains in recept
Externí odkaz:
https://doaj.org/article/94f2e00f96ba4e7fa260348eccb179cb
Autor:
Milos B Rokic, Stanko S Stojilkovic, Vojtech Vavra, Pavlo Kuzyk, Vendula Tvrdonova, Hana Zemkova
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59411 (2013)
The binding of ATP to trimeric P2X receptors (P2XR) causes an enlargement of the receptor extracellular vestibule, leading to opening of the cation-selective transmembrane pore, but specific roles of vestibule amino acid residues in receptor activati
Externí odkaz:
https://doaj.org/article/081dabe40dc14e78b81511d8ba99149a