Rationale and design of the BeyeOMARKER study: prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer's disease pathology in the eye clinic.

Autor: Bader I; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands. ilse.bader@amsterdamumc.nl.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands. ilse.bader@amsterdamumc.nl.; Department of Ophthalmology, Bergman Clinics, Amsterdam, 1101 BM, The Netherlands. ilse.bader@amsterdamumc.nl., Groot C; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands., Tan HS; Department of Ophthalmology, Bergman Clinics, Amsterdam, 1101 BM, The Netherlands.; Department of Ophthalmology, Amsterdam UMC, Amsterdam, 1081 HV, The Netherlands.; Amsterdam Neuroscience, Brain Imaging, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands.; Amsterdam UMC Location VUmc, Amsterdam Reproduction and Development Research Institute, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands., Milongo JA; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands.; Department of Ophthalmology, Bergman Clinics, Amsterdam, 1101 BM, The Netherlands., Haan JD; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands., Verberk IMW; Neurochemistry Laboratory, Laboratory Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, 1081 HV, The Netherlands., Yong K; Queen Square Institute of Neurology, Dementia Research Centre, London, WC1N 3BG, UK., Orellina J; Optina Diagnostics, Montréal, QC, Canada., Campbell S; Optina Diagnostics, Montréal, QC, Canada., Wilson D; Quanterix Corporation, Billerica, MA, USA., van Harten AC; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands., Kok PHB; Department of Ophthalmology, Bergman Clinics, Amsterdam, 1101 BM, The Netherlands., van der Flier WM; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands.; Epidemiology and Data Science, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, 1081 HV, The Netherlands., Pijnenburg YAL; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands., Barkhof F; Amsterdam Neuroscience, Brain Imaging, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands.; Radiology & Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, 1081 HZ, The Netherlands.; UCL Queen Square Institute of Neurology and Centre for Medical Image Computing, University College, London, WC1N 3BG, UK., van de Giessen E; Amsterdam Neuroscience, Brain Imaging, Vrije Universiteit Amsterdam, Amsterdam, 1081 HV, The Netherlands.; Radiology & Nuclear Medicine, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, 1081 HZ, The Netherlands., Teunissen CE; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands.; Neurochemistry Laboratory, Laboratory Medicine, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC Location VUmc, Amsterdam, 1081 HV, The Netherlands., Bouwman FH; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands., Ossenkoppele R; Amsterdam Neuroscience, Neurodegeneration, Amsterdam, 1081 HV, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, 1081 HZ, The Netherlands. r.ossenkoppele@amsterdamumc.nl.; Clinical Memory Research Unit, Lund University, Lund, Sweden. r.ossenkoppele@amsterdamumc.nl.

Publikováno v: Alzheimer's research & therapy [Alzheimers Res Ther] 2024 Aug 21; Vol. 16 (1), pp. 190. Date of Electronic Publication: 2024 Aug 21.