Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Miloš Hroch"'
Autor:
Martin Uher, Miloš Hroch, Rozálie Peřinová, Radim Havelek, Jana Křoustková, Martina Řezáčová, Darina Muthná, Darja Koutová, Jiří Kuneš, Lucie Cahlíková
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 5, Pp 103746- (2022)
In this study, a new series of aliphatic, cyclic, and heterocyclic derivatives of haemanthamine was designed and synthesized to enhance its inhibitory effect on the proliferation and viability of cancer cells. A library of haemanthamine derivatives w
Externí odkaz:
https://doaj.org/article/0b444150ae55421aa2d68d3af1eaeb57
Autor:
Miloš Hroch
Publikováno v:
Forum Historiae, Vol 14, Iss 1, Pp 17-27 (2020)
The importance of zines – as documents of history and contemporary media – has recognisably increased in the past decade, and not only media scholars but also historians are paying closer attention to this type of alternative media. We have witne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::344435152e9f75098fd15468b5aa5332
http://www.forumhistoriae.sk/sk/clanok/not-out-date-out-time-materiality-zines-and-post-digital-memory
http://www.forumhistoriae.sk/sk/clanok/not-out-date-out-time-materiality-zines-and-post-digital-memory
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 219:114923
Liquid-liquid extraction methods are widely used for sample treatment in bioanalysis, although their implementation poses a common speed-limiting step in the analytical process when fast separation and detection methods such as UHPLC-MS are used. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b2a2af1bd45f8f7b55e7504ffc5bac
https://doi.org/10.1016/j.jpba.2022.114923
https://doi.org/10.1016/j.jpba.2022.114923
Publikováno v:
Journal of labelled compoundsradiopharmaceuticalsREFERENCES. 64(13)
Convenient and straightforward synthesis of ibrutinib labeled by carbon-13 isotope is reported. Isotopically labeled building block is introduced in the last step of reaction sequence affording sufficient isolated yield (7%) of [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1bd3fbf6da71a42ae468e2d37d0662c5
https://pubmed.ncbi.nlm.nih.gov/34478181
https://pubmed.ncbi.nlm.nih.gov/34478181
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 206
At present, therapeutic drug monitoring is the standard in pharmacotherapy using medications with a narrow therapeutic index or showing serious adverse effects, such as in the case of ibrutinib. A technique commonly used for this purpose is liquid ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7cd6796056680492da44dc5305ac6c4
https://pubmed.ncbi.nlm.nih.gov/34555634
https://pubmed.ncbi.nlm.nih.gov/34555634
Autor:
Miloš Hroch
Publikováno v:
Český lid. 106:29-47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6248ada33868ba34d720c26e32977eb5
https://doi.org/10.21104/cl.2019.1.02
https://doi.org/10.21104/cl.2019.1.02
Autor:
Miloš, Hroch, Stanislav, Mičuda, Radim, Havelek, Jolana, Cermanová, Lucie, Cahlíková, Anna, Hošťálková, Daniela, Hulcová, Martina, Řezáčová
Publikováno v:
Biomedical chromatography : BMC. 30(7)
Evidence gathered in various studies points to the fact that haemanthamine, an isoquinoline alkaloid, has multiple medicinally interesting characteristics, including antitumor, antileukemic, antioxidant, antiviral, anticonvulsant and antimalarial act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b951eaff907c4ab507b049488fb10a10
https://pubmed.ncbi.nlm.nih.gov/26577707
https://pubmed.ncbi.nlm.nih.gov/26577707
Autor:
Jiří, Grim, Miloš, Hroch, Hroch, Miloš, Jaroslav, Chládek, Chládek, Jaroslav, Jiří, Petera, Petera, Jiří, Jiřina, Martínková, Martínková, Jiřina
Publikováno v:
Clinical pharmacokinetics. 54(5)
This study estimated patients' early response following neoadjuvant chemoradiotherapy (CHRT) of locally advanced rectal cancer based on 5-fluorouracil (5-FU). The target was to achieve pathological complete response (pCR; residual disease-free stage)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e3273b9572aa706d2a924244dd01d8
https://pubmed.ncbi.nlm.nih.gov/25791896
https://pubmed.ncbi.nlm.nih.gov/25791896
Autor:
Ivone Cristina Igreja Sá, Katarina Tripska, Fatemeh Alaei Faradonbeh, Milos Hroch, Hana Lastuvkova, Jolana Schreiberova, Marian Kacerovsky, Miguel Pericacho, Petr Nachtigal, Stanislav Micuda
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Labetalol is used for the therapy of hypertension in preeclampsia. Preeclampsia is characterized by high soluble endoglin (sEng) concentration in plasma and coincides with intrahepatic cholestasis during pregnancy (ICP), which threatens the fetus wit
Externí odkaz:
https://doaj.org/article/ea424a9206d44bdd945e03f9a6b3ed54
Autor:
Fatemeh Alaei Faradonbeh, Hana Lastuvkova, Jolana Cermanova, Milos Hroch, Zuzana Nova, Martin Uher, Petra Hirsova, Petr Pavek, Stanislav Micuda
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Multidrug resistance-associated protein 2 (Mrp2) mediates biliary secretion of anionic endobiotics and xenobiotics. Genetic alteration of Mrp2 leads to conjugated hyperbilirubinemia and predisposes to the development of intrahepatic cholestasis of pr
Externí odkaz:
https://doaj.org/article/3d846cddeca1478a836441a3e6a261b4