Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Milly M. Choy"'
Autor:
Kitti Wing Ki Chan, Amanda Makha Bifani, Satoru Watanabe, Milly M. Choy, Eng Eong Ooi, Subhash G. Vasudevan
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104570- (2023)
Summary: Background: The Asian lineage Zika virus (ZIKV) emerged as a public health emergency in 2016 causing severe neurological pathologies with no apparent historical correlate to the mild, disease-causing innocuous member of the mosquito-borne fl
Externí odkaz:
https://doaj.org/article/e0ba4fa07bca438c88084c5164343c21
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-8 (2021)
Abstract Dengue poses a significant burden of individual health, health systems and the economy in dengue endemic regions. As such, dengue vaccine development has been an active area of research. Previous studies selected attenuated vaccine candidate
Externí odkaz:
https://doaj.org/article/e74404e1387b4601ad89e5f5720fa7a9
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Dengue virus (DENV) is the most common arbovirus, causing a significant burden on both the economy and global healthcare systems. The virus is transmitted by Aedes species of mosquitoes as a swarm of closely related virus genomes, collectively referr
Externí odkaz:
https://doaj.org/article/5f6b9606603e46d28cbfd4c40071ea88
Autor:
Roland G. Huber, Xin Ni Lim, Wy Ching Ng, Adelene Y. L. Sim, Hui Xian Poh, Yang Shen, Su Ying Lim, Karin B. Sundstrom, Xuyang Sun, Jong Ghut Aw, Horng Khit Too, Peng Hee Boey, Andreas Wilm, Tanu Chawla, Milly M. Choy, Lu Jiang, Paola Florez de Sessions, Xian Jun Loh, Sylvie Alonso, Martin Hibberd, Niranjan Nagarajan, Eng Eong Ooi, Peter J. Bond, October M. Sessions, Yue Wan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Here, the authors provide detailed analyses of viral RNA structure in virions and in infected cells for four dengue virus serotypes and four Zika virus strains, and identify conserved structures that are important for virus replication.
Externí odkaz:
https://doaj.org/article/e1ccb23a51bc41a7a660d2410dfdbfec
Autor:
Bing Liang Alvin Chew, AN Qi Ngoh, Wint Wint Phoo, Kitti Wing Ki Chan, Zheng Ser, Nikhil K Tulsian, Shiao See Lim, Mei Jie Grace Weng, Satoru Watanabe, Milly M Choy, Jenny Low, Eng Eong Ooi, Christiane Ruedl, Radoslaw M Sobota, Subhash G Vasudevan, Dahai Luo
Publikováno v:
eLife, Vol 12 (2024)
Severe dengue infections are characterized by endothelial dysfunction shown to be associated with the secreted nonstructural protein 1 (sNS1), making it an attractive vaccine antigen and biotherapeutic target. To uncover the biologically relevant str
Externí odkaz:
https://doaj.org/article/7d2b25b34b2d403fb3d814958e7d8555
Autor:
Sai Wang, Marie Jennifer Reolo, Ann-Marie Chacko, Min Jie Alvin Tan, Satoru Watanabe, Milly M. Choy, Carla Bianca Luena Victorio, Menchie Manuel, Subhash G. Vasudevan, Kitti Wing Ki Chan, Colin X Cheng, Joanne Ong
Publikováno v:
ACS Infectious Diseases. 7:3277-3291
Dengue virus (DENV) non-structural protein 5 (NS5) is critical for viral RNA synthesis within endoplasmic reticulum (ER)-derived replication complexes in the cytoplasm; however a proportion of NS5 is known to be localized to the nucleus of infected c
Autor:
Ban H. Tan, Raymond T. P. Lin, Jean X.Y. Sim, Jenny G. Low, Milly M. Choy, Quan Y. Ho, Eng Eong Ooi, Terence Kee, Hei M. Wong, Esther S. Gan, Hwee C. Tan, Sobhana Thangaraju
Publikováno v:
American Journal of Transplantation. 21:1944-1947
Dengue virus (DENV), a mosquito-borne pathogen, causes systemic infections. There are no clear guidelines regarding the screening of donor blood is used in endemic countries to prevent blood transfusion or transplant-associated dengue. DENV has been
Autor:
Amanda Makha, Bifani, Kitti Wing Ki, Chan, Doortje, Borrenberghs, Min Jie Alvin, Tan, Wint Wint, Phoo, Satoru, Watanabe, Olivia, Goethals, Subhash G, Vasudevan, Milly M, Choy
Publikováno v:
Antiviral Research. 210:105517
Flaviviruses are vector-borne pathogens capable of causing devastating human diseases. The re-emergence of Zika in 2016 notoriously led to a widescale epidemic in the Americas. New daunting evidence suggests that a single mutation in Zika virus genom
Autor:
Bing Liang Alvin Chew, An Qi Ngoh, Wint Wint Phoo, Wing Ki Kitti Chan, Zheng Ser, Shiao See Lim, Meng Jie Grace Weng, Satoru Watanabe, Milly M. Choy, Jenny G. Low, Eng Eong Ooi, Radoslaw M. Sobota, Subhash G. Vasudevan, Dahai Luo
Severe dengue infections are characterized by endothelial dysfunction shown to be associated with the secreted nonstructural protein 1 (sNS1), making it an attractive vaccine antigen and biotherapeutic target. To uncover the biologically relevant str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ceeb8814b2930fa3974fb33866bc06
https://doi.org/10.1101/2022.04.06.487425
https://doi.org/10.1101/2022.04.06.487425
Autor:
Milly M Choy, Summer L Zhang, Vivian V Costa, Hwee Cheng Tan, Sophie Horrevorts, Eng Eong Ooi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004058 (2015)
The mosquito-borne dengue virus (DENV) is a cause of significant global health burden, with an estimated 390 million infections occurring annually. However, no licensed vaccine or specific antiviral treatment for dengue is available. DENV interacts w
Externí odkaz:
https://doaj.org/article/150dfb85b39f4fe681b93e53c765c818