Immunostimulatory nucleic acid nanoparticles (NANPs) augment protective osteoblast and osteoclast type I interferon responses to Staphylococcus aureus.

Autor: Mills EL; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: edavi138@charlotte.edu., Avila YI; Department of Chemistry, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: yavila@charlotte.edu., Beasock D; Department of Chemistry, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223., Radwan Y; Department of Chemistry, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: yradwan@uncc.edu., Suptela SR; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: srfurr1@charlotte.edu., Marriott I; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: imarriot@charlotte.edu., Afonin KA; Department of Chemistry, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: kafonin@charlotte.edu., Johnson MB; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA, 28223. Electronic address: mjohn398@charlotte.edu.

Publikováno v: Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2024 Aug; Vol. 60, pp. 102762. Date of Electronic Publication: 2024 Jun 10.

BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis.

Autor: Verkerke ARP; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Wang D; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Yoshida N; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Taxin ZH; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Shi X; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Zheng S; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Li Y; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan., Auger C; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Oikawa S; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Yook JS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., Granath-Panelo M; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA., He W; Duke Molecular Physiology Institute, Duke School of Medicine, Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University, Durham, NC, USA., Zhang GF; Duke Molecular Physiology Institute, Duke School of Medicine, Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University, Durham, NC, USA., Matsushita M; Department of Nutrition, School of Nursing and Nutrition, Tenshi College, Sapporo, Japan., Saito M; Laboratory of Biochemistry, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan., Gerszten RE; Division of Cardiovascular Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Mills EL; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute and Department of Immunology, Harvard Medical School, Boston, MA, USA., Banks AS; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA., Ishihama Y; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan., White PJ; Duke Molecular Physiology Institute, Duke School of Medicine, Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, USA., McGarrah RW; Duke Molecular Physiology Institute, Duke School of Medicine, Sarah W. Stedman Nutrition and Metabolism Center, Department of Medicine, Division of Cardiology, Duke University, Durham, NC, USA., Yoneshiro T; Division of Metabolic Medicine, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan; Division of Molecular Physiology and Metabolism, Tohoku University Graduate School of Medicine, Sendai, Japan., Kajimura S; Division of Endocrinology, Diabetes and Metabolism, Beth Israel Deaconess Medical Center and Harvard Medical School, and Howard Hughes Medical Institute, Boston, MA, USA. Electronic address: skajimur@bidmc.harvard.edu.

Publikováno v: Cell [Cell] 2024 May 09; Vol. 187 (10), pp. 2359-2374.e18. Date of Electronic Publication: 2024 Apr 22.

Minimally Invasive Mitral Valve Repair Using Transcatheter Chordal Attachments.

Autor: Das C; Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L353, Portland, OR 97239, USA., Al Awwa G; Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L353, Portland, OR 97239, USA., Mills EL; Knight Cardiovascular Institute, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mail Code UHN-62, Portland, OR 97239, USA., Lantz G; Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mail Code L353, Portland, OR 97239, USA. Electronic address: lantz@ohsu.edu.

Publikováno v: Interventional cardiology clinics [Interv Cardiol Clin] 2024 Apr; Vol. 13 (2), pp. 257-269. Date of Electronic Publication: 2024 Jan 25.

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Lactate regulates cell cycle by remodelling the anaphase promoting complex.

Autor: Liu W; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Department of Musculoskeletal Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Wang Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-sen University, Guangzhou, China., Bozi LHM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Fischer PD; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.; Department of Pharmacy, Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken, Germany., Jedrychowski MP; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Xiao H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Wu T; Department of Systems Biology, Harvard Medical School, Boston, MA, USA., Darabedian N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., He X; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Mills EL; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Burger N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Shin S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Reddy A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Sprenger HG; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Tran N; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Winther S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Hinshaw SM; Stanford Cancer Institute, School of Medicine, Stanford University, Stanford, CA, USA., Shen J; Department of Musculoskeletal Oncology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Seo HS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Song K; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Xu AZ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Sebastian L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Dhe-Paganon S; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Che J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA., Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Arthanari H; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA., Chouchani ET; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. edwardt_chouchani@dfci.harvard.edu.

Publikováno v: Nature [Nature] 2023 Apr; Vol. 616 (7958), pp. 790-797. Date of Electronic Publication: 2023 Mar 15.