Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Millinghoffer A"'
Autor:
Andras Gezsi, Sandra Van der Auwera, Hannu Mäkinen, Nora Eszlari, Gabor Hullam, Tamas Nagy, Sarah Bonk, Rubèn González-Colom, Xenia Gonda, Linda Garvert, Teemu Paajanen, Zsofia Gal, Kevin Kirchner, Andras Millinghoffer, Carsten O. Schmidt, Bence Bolgar, Josep Roca, Isaac Cano, Mikko Kuokkanen, Peter Antal, Gabriella Juhasz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The heterogeneity and complexity of symptom presentation, comorbidities and genetic factors pose challenges to the identification of biological mechanisms underlying complex diseases. Current approaches used to identify biological subtypes o
Externí odkaz:
https://doaj.org/article/43fb0a77e0ce443aa7add873f517e19c
Autor:
Nora Eszlari, Gabor Hullam, Zsofia Gal, Dora Torok, Tamas Nagy, Andras Millinghoffer, Daniel Baksa, Xenia Gonda, Peter Antal, Gyorgy Bagdy, Gabriella Juhasz
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Most current approaches to establish subgroups of depressed patients for precision medicine aim to rely on biomarkers that require highly specialized assessment. Our present aim was to stratify participants of the UK Biobank cohort based on
Externí odkaz:
https://doaj.org/article/9d0da3c777a246f2a7e93175e010a3f7
Autor:
Bence Bruncsics, Gabor Hullam, Bence Bolgar, Peter Petschner, Andras Millinghoffer, Kinga Gecse, Nora Eszlari, Xenia Gonda, Debra J. Jones, Sorrel T. Burden, Peter Antal, Bill Deakin, Gyorgy Bagdy, Gabriella Juhasz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Manipulation of intake of serotonin precursor tryptophan has been exploited to rapidly induce and alleviate depression symptoms. While studies show that this latter effect is dependent on genetic vulnerability to depression, the effect of ha
Externí odkaz:
https://doaj.org/article/d90211f53735498d8257a1b5d6fd8a0b
Akademický článek
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Publikováno v:
European Psychiatry, Vol 66, Pp S352-S353 (2023)
Introduction Depression shows a moderate heritability of 37-42%, which can be up to 75% in severely depressed samples 75%. At the same time SNP-based heritability of depression in GWAS-s is around 8-9%. Heterogeneity of the depressive phenotype may c
Externí odkaz:
https://doaj.org/article/fa3b33f72f1e48b89806b4bf7ac1877c
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Autor:
Xenia Gonda, Nora Eszlari, Dora Torok, Zsofia Gal, Janos Bokor, Andras Millinghoffer, Daniel Baksa, Peter Petschner, Peter Antal, Gerome Breen, Gabriella Juhasz, Gyorgy Bagdy
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Although recently a large-sample GWASs identified significant loci in the background of depression, the heterogeneity of the depressive phenotype and the lack of accurate phenotyping hinders applicability of findings. We carried out a pilot
Externí odkaz:
https://doaj.org/article/e789f91d07334a91b96c061f3dd0c487
Publikováno v:
European Psychiatry, Vol 65, Pp S228-S229 (2022)
Introduction Catenin alpha 2 gene (CTNNA2) is important in the stability of hippocampal synapses and also in brain development. Our recent paper (Eszlari et al, Pharmaceuticals 2021, 14, 850) has demonstrated that rumination on sad mood mediates the
Externí odkaz:
https://doaj.org/article/fcc344037212494ea3881513bee98ddf
Publikováno v:
European Psychiatry, Vol 65, Pp S18-S19 (2022)
One reason behind the failure to understand the neurobiological background of affective disorders and develop more effective treatments is their heterogeneity warranting identification of clinically meaningful endophenotypes. Affective temperaments,
Externí odkaz:
https://doaj.org/article/63e22497844348a0a83a24eb0086d4ae
Autor:
Péter P. Ujma, Nóra Eszlári, András Millinghoffer, Bence Bruncsics, Dóra Török, Péter Petschner, Péter Antal, Bill Deakin, Gerome Breen, György Bagdy, Gabriella Juhász
Publikováno v:
Brain and Behavior, Vol 12, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Educational attainment is a substantially heritable trait, and it has recently been linked to specific genetic variants by genome‐wide association studies (GWASs). However, the effects of such genetic variants are expected to
Externí odkaz:
https://doaj.org/article/361c85f92e23431795abd9f73d6f0849