Regioselective addition of Grignard reagents to N -acylpyrazinium salts: synthesis of substituted 1,2-dihydropyrazines and Δ ⁵ -2-oxopiperazines.

Autor: St Hilaire VR; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina 27707, United States., Hopkins WE; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina 27707, United States., Miller YS; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina 27707, United States., Dandepally SR; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina 27707, United States., Williams AL; Biomanufacturing Research Institute and Technology Enterprise (BRITE), North Carolina Central University, Durham, North Carolina 27707, United States.; Department of Pharmaceutical Sciences, North Carolina Central University, Durham, North Carolina 27707, United States.

Publikováno v: Beilstein journal of organic chemistry [Beilstein J Org Chem] 2019 Jan 08; Vol. 15, pp. 72-78. Date of Electronic Publication: 2019 Jan 08 (Print Publication: 2019).