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Ubiquitin-interacting motifs inhibit aggregation of polyQ-expanded huntingtin.

Autor: Miller SLH; Laboratory of Signal Transduction, NIEHS, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709., Scappini EL; Laboratory of Signal Transduction, NIEHS, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709., O'Bryan J; Laboratory of Signal Transduction, NIEHS, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina 27709; Department of Pharmacology, University of Illinois College of Medicine, Chicago, Illinois 60612. Electronic address: obryanj@uic.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2007 Mar 30; Vol. 282 (13), pp. 10096-10103. Date of Electronic Publication: 2007 Feb 02.